Prescription Histories and Dose Strengths Associated with Overdose Deaths

Pain Medicine (United States)

Volumn 15, Issue 7, 2014, Pages 1187-1195

  Hirsch, Anne ^a   Proescholdbell, Scott K ^b   Bronson, William ^c   Dasgupta, Nabarun ^d  

^a CDC CSTE Applied Epidemiology Fellowship   (United States)

^b Division of Public Health   (United States)

^c University of North Carolina ^*  (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Epidemiology; Fentanyl; Methadone; Morphine; Mortality; Opioids; Overdose; Oxycodone; Oxymorphone

Indexed keywords

ALPRAZOLAM; FENTANYL; HYDROCODONE; METHADONE; MORPHINE; OXYCODONE; OXYMORPHONE; PRESCRIPTION DRUG; NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; DRUG MONITORING; DRUG OVERDOSE; FEMALE; HISTORY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MORTALITY; NEWBORN; PRESCRIPTION; RETROSPECTIVE STUDY; UNITED STATES; VITAL STATISTICS; MIDDLE AGED;

ADULT; ANALGESICS, OPIOID; DRUG OVERDOSE; FEMALE; HUMANS; MALE; MIDDLE AGED; NORTH CAROLINA; PRESCRIPTION DRUGS; RETROSPECTIVE STUDIES;

EID: 84904820028     PISSN: 15262375     EISSN: 15264637     Source Type: Journal    
DOI: 10.1111/pme.12391     Document Type: Article

References (20)

1. Fischer B, Jones W, Rehm J. High correlations between levels of consumption and mortality related to strong prescription opioid analgesics in British Columbia and Ontario, 2005-2009. Pharmacoepidemiol Drug Saf 2013;22:438-442.
2. Dasgupta N, Kramer ED, Zalman MA, etal. Association between non-medical and prescriptive usage of opioids. Drug Alcohol Depend 2006;82:135-142.
3. Johnson EM, Lanier WA, Merrill RM, etal. Unintentional prescription opioid-related overdose deaths: description of decedents by next of kin or best contact, Utah, 2008-2009. J Gen Intern Med 2013;28:522-529.
4. Joranson DE, Ryan KM, Gilson AM, Dahl JL. Trends in medical use and abuse of opioid analgesics. JAMA 2000;283:1710-1714.
5. Modarai F, Mack K, Hicks P, etal. Relationship of opioid prescription sales and overdoses, North Carolina. Drug Alcohol Depend 2013;132:81-86.
6. Paulozzi LJ, Budnitz DS, Xi Y. Increasing deaths from opioid analgesics in the United States. Pharmacoepidemiol Drug Saf 2006;15:618-627.
7. Paulozzi LJ, Ryan GW. Opioid analgesics and rates of fatal drug poisoning in the United States. Am J Prev Med 2006;31:506-511.
8. Paulozzi LJ, Weisler RH, Patkar AA. A national epidemic of unintentional prescription opioid overdose deaths: how physicians can help control it. J Clin Psychiatry 2011;72:589-592.
9. Porucznik CA, Johnson EM, Sauer B, Crook J, Rolfs RT. Studying adverse events related to prescription opioids: The utah experience. Pain Med 2011;12(suppl 2):S16-25.
10. Sims SA, Snow LA, Porucznik CA. Surveillance of methadone-related adverse drug events using multiple public health data sources. J Biomed Inform 2007;40:382-389.
11. Bohnert AS, Valenstein M, Bair MJ, etal. Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA 2011;305:1315-1321.
12. Dunn KM, Saunders KW, Rutter CM, etal. Opioid prescriptions for chronic pain and overdose: A cohort study. Ann Intern Med 2010;152:85-92.
13. Gomes T, Juurlink DN, Dhalla IA, etal. Trends in opioid use and dosing among socio-economically disadvantaged patients. Open Med 2011;5:e13-22.
14. Gomes T, Mamdani MM, Dhalla IA, Paterson JM, Juurlink DN. Opioid dose and drug-related mortality in patients with nonmalignant pain. Arch Intern Med 2011;171:686-691.
15. Paulozzi LJ, Kilbourne EM, Shah NG, etal. A history of being prescribed controlled substances and risk of drug overdose death. Pain Med 2012;13:87-95.
16. Institute of Medicine. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research. Washington, DC: National Academies Press; 2011.
17. Dasgupta N, Henningfield JE, Ertischek MD, Schnoll SH. When drugs in the same controlled substance schedule differ in real-world abuse, should they be differentiated in labeling? Drug Alcohol Depend 2011;119:e1-e4.
18. Hall AJ, Logan JE, Toblin RL, etal. Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA 2008;300:2613-2620.
19. Dasgupta N. Opioid analgesic prescribing and overdose mortality in North Carolina. Chapel Hill: University of North Carolina; 2013. 125 p.
20. Nicholson SC, Evanyo K, Salinas GD, etal. Extended-release/long-acting opioid REMS may fill the need for prescribers' appropriate use education. J Opioid Manag 2012;8:212-216.