Oesophageal varices, schistosomiasis, and mortality among patients admitted with haematemesis in Mwanza, Tanzania: A prospective cohort study

BMC Infectious Diseases

Volumn 14, Issue 1, 2014, Pages

  Chofle, Awilly A ^a   Jaka, Hyasinta ^a,b   Koy, Mheta ^a,b   Smart, Luke R ^a,b,c   Kabangila, Rodrick ^a,b   Ewings, Fiona M ^d,e   Mazigo, Humphrey D ^b   Johnson, Warren D ^c   Fitzgerald, Daniel W ^c   Peck, Robert N ^a,b,c   Downs, Jennifer A ^a,b,c  

^a Bugando Medical Centre   (Tanzania)

^b CATHOLIC UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e National Institute for Medical Research   (Tanzania)

Author keywords

Mortality; Prospective; Schistosomiasis; Tanzania; Ultrasound; Upper gastrointestinal bleeding

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CIRCULATING CATHODIC ANTIGEN; HEMOGLOBIN; PARASITE ANTIGEN; PRAZIQUANTEL; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; ASCITES; BRAIN DISEASE; CLINICAL EXAMINATION; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ECHOGRAPHY; ESOPHAGUS VARICES; FEMALE; FOLLOW UP; GASTROINTESTINAL ENDOSCOPY; HEMATEMESIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; MEAN CORPUSCULAR VOLUME; MIDDLE AGED; MORTALITY; OUTCOME ASSESSMENT; PATIENT HISTORY OF CHEMOTHERAPY; PATIENT IDENTIFICATION; PEPTIC ULCER BLEEDING; PORTAL VEIN; PREDICTIVE VALUE; PREVALENCE; PROSPECTIVE STUDY; SCHISTOSOMIASIS; SENSITIVITY AND SPECIFICITY; SPLENOMEGALY; STOMACH SURGERY; TANZANIA; UPPER GASTROINTESTINAL BLEEDING; VEIN DIAMETER; WATER SUPPLY; COMPLICATION; ESOPHAGEAL AND GASTRIC VARICES; GASTROINTESTINAL HEMORRHAGE; HOSPITALIZATION; STATISTICAL MODEL;

ADULT; COHORT STUDIES; ESOPHAGEAL AND GASTRIC VARICES; FEMALE; GASTROINTESTINAL HEMORRHAGE; HOSPITALIZATION; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES; SCHISTOSOMIASIS; TANZANIA;

EID: 84904766560     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-14-303     Document Type: Article

References (30)

1. Bush EL, Shapiro ML. Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management 2010, 223. New York: Springer: Pryor AD, Pappas TN, Branch MS.
2. Laine L. Harrison's Principles of Internal Medicine. 2008, 2958. New York: McGraw-Hill, Fauci A, Kasper D, Longo D, Braunwald E, Hauser S, Jameson J, Loscalzo J, 17.
3. Theocharis GJ, Thomopoulos KC, Sakellaropoulos G, Katsakoulis E, Nikolopoulou V. Changing trends in the epidemiology and clinical outcome of acute upper gastrointestinal bleeding in a defined geographical area in Greece. J Clin Gastroenterol 2008, 42:128-133. 10.1097/01.mcg.0000248004.73075.ad, 18209579.
4. Van Leerdam ME, Vreeburg EM, Rauws EAJ, Geraedts AAM, Tijssen JGP, Reitsma JB, Tytgat GNJ. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000. Am J Gastroenterol 2003, 98:1494-1499.
5. Peck RN, Green E, Mtabaji J, Majinge C, Smart LR, Downs JA, Fitzgerald DW. Hypertension-related diseases as a common cause of hospital mortality in Tanzania: a 3-year prospective study. J Hypertens 2013, 31:1806-1811. 10.1097/HJH.0b013e328362bad7, 4005815, 23777761.
6. Elghuel A. The characteristics of adults with upper gastrointestinal bleeding admitted to Tripoli Medical Center: a retrospective case-series analysis. Libyan J Med 2011, 6:1-5.
7. Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Ann Intern Med 1995, 123:280-287. 10.7326/0003-4819-123-4-199508150-00007, 7611595.
8. Suba M, Ayana SM, Mtabho CM, Kibiki GS. The aetiology, management and clinical outcome of upper gastrointestinal bleeding among patients admitted at the Kilimanjaro Christian Medical Centre in Moshi, Tanzania. Tanzania J Heal Res 2010,
9. Jaka H, Koy M, Liwa A, Kabangila R, Mirambo M, Scheppach W, Mkongo E, McHembe MD, Chalya PL. A fibreoptic endoscopic study of upper gastrointestinal bleeding at Bugando Medical Centre in northwestern Tanzania: a retrospective review of 240 cases. BMC Res Notes 2012, 5:200. 10.1186/1756-0500-5-200, 3392734, 22537571.
10. Loperfido S, Baldo V, Piovesana E, Bellina L, Rossi K, Groppo M, Caroli A, Dal Bò N, Monica F, Fabris L, Salvat HH, Bassi N, Okolicsanyi L. Changing trends in acute upper-GI bleeding: a population-based study. Gastrointest Endosc 2009, 70:212-24. 10.1016/j.gie.2008.10.051, 19409558.
11. Hreinsson JP, Kalaitzakis E, Gudmundsson S, Björnsson ES. Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting. Scand J Gastroenterol 2013, 48:439-47. 10.3109/00365521.2012.763174, 3613943, 23356751.
12. Clements ACA, Lwambo NJS, Blair L, Nyandindi U, Kaatano G, Kinung'hi S, Webster JP, Fenwick A, Brooker S. Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania. Trop Med Int Heal 2006, 11:490-503.
13. Mazigo HD, Nuwaha F, Kinung'hi SM, Morona D, Pinot de Moira A, Wilson S, Heukelbach J, Dunne DW. Epidemiology and control of human schistosomiasis in Tanzania. Parasit Vectors 2012, 5:274. 10.1186/1756-3305-5-274, 3549774, 23192005.
14. Downs J, Van Dam G, Changalucha J, Corstjens P, Peck R, De Dood C, Bang H, Andreasen A, Kalluvya S, Van Lieshout L, Johnson WJ, Fitzgerald D. Association of Schistosomiasis and HIV infection in Tanzania. Am J Trop Med Hyg 2012, Nov, 87:868-73.
15. Jacobs B, Mayaud P, Changalucha J, Todd J, Ka-Gina G, Grosskurth HBZ. Sexual transmission of hepatitis B in Mwanza. Sex Transm Dis 1997, 24:121-126. 10.1097/00007435-199703000-00001, 9132977.
16. Smith JL, Graham DY. Variceal hemorrhage: a critical evaluation of survival analysis. Gastroenterology 1982, 82(5 Pt 1):968-73.
17. Obeng BB, Aryeetey YA, De Dood CJ, Amoah AS, Larbi IA, Deelder AM, Yazdanbakhsh M, Hartgers FC, Boakye DA, Verweij JJ, Van Dam GJ, Van Lieshout L. Application of a circulating-cathodic-antigen (CCA) strip test and real-time PCR, in comparison with microscopy, for the detection of Schistosoma haematobium in urine samples from Ghana. Ann Trop Med Parasitol 2008, 102:625-33. 10.1179/136485908X337490, 18817603.
18. Stothard JR, Sousa-Figueiredo JC, Standley C, Van Dam GJ, Knopp S, Utzinger J, Ameri H, Khamis AN, Khamis IS, Deelder AM, Mohammed KA, Rollinson D. An evaluation of urine-CCA strip test and fingerprick blood SEA-ELISA for detection of urinary schistosomiasis in schoolchildren in Zanzibar. Acta Trop 2009, 111:64-70. 10.1016/j.actatropica.2009.02.009, 19426665.
19. Ashton RA, Stewart BT, Petty N, Lado M, Finn T, Brooker S, Kolaczinski JH. Accuracy of circulating cathodic antigen tests for rapid mapping of Schistosoma mansoni and S. haematobium infections in Southern Sudan. Trop Med Int Heal 2011, 16:1099-103.
20. Colley DG, Binder S, Campbell C, King CH, Tchuem Tchuenté L-A, N'Goran EK, Erko B, Karanja DMS, Kabatereine NB, Van Lieshout L, Rathbun S. A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of Schistosoma mansoni. PLoS Negl Trop Dis 2013, 7(1):e2008. doi 10137 2013, 88:426-32, 10.1371/journal.pntd.0002008, 3554525, 23359826.
21. Oxford Poverty & Human Development Initiative (OPHI) http://www.ophi.org.uk/.
22. Van der Werf MJ, De Vlas SJ, Brooker S, Looman CWN, Nagelkerke NJD, Habbema JDF, Engels D. Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Trop 2003, 86:125-39. 10.1016/S0001-706X(03)00029-9, 12745133.
23. Chalasani N, Kahi C, Francois F, Pinto A, Marathe A, Bini EJ, Pandya P, Sitaraman S, Shen J. Improved patient survival after acute variceal bleeding: a multicenter, cohort study. Am J Gastroenterol 2003, 98:653-9. 10.1111/j.1572-0241.2003.07294.x, 12650802.
24. Limquiaco J, Nolasco ER, Daez MLO, Gloria VI, Domingo EO, Banez VP, Zano FM, Atienza MA, Sy PP, Labio E, Comia AC, De Lusong MAA, Jun P, Sherwin F, Elmer Cabanayan PAP. Clinical predictors of bleeding from esophageal varices. Phil J Gastroenterol 2006, 2:103-111.
25. Thomopoulos K, Theocharis G, Mimidis K, Lampropoulou-Karatza C, Alexandridis E, Nikolopoulou V. Improved survival of patients presenting with acute variceal bleeding. Prognostic indicators of short- and long-term mortality. Dig Liver Dis 2006, 38:899-904. 10.1016/j.dld.2006.08.002, 17005458.
26. Gryseels B, Polman K, Clerinx J, Kestens L. Human schistosomiasis. Lancet 2006, 368:1106-18. 10.1016/S0140-6736(06)69440-3, 16997665.
27. Woolhouse ME, Taylor P, Matanhire D, Chandiwana SK. Acquired immunity and epidemiology of Schistosoma haematobium. Nature 1991, 351:757-9. 10.1038/351757a0, 1905786.
28. Andrade ZA, Baptista AP, Santana TS. Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis. Mem Inst Oswaldo Cruz 2006, 101Suppl(Popper 1977):267-72.
29. Vennervald B, Booth M, Butterworth A, Kariuki H, Kadzo H, Ireri E, Amaganga C, Kimani G, Kenty L, Mwatha J, Ouma J, Dunne D. Regression of hepatosplenomegaly in. Trans R Soc Trop Med Hyg 2005, 99:150-160. 10.1016/j.trstmh.2004.06.009, 15607341.
30. Schistosomiasis: Epidemiological Situation http://www.who.int/schistosomiasis/epidemiology/en.