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Volumn 35, Issue 6, 2014, Pages 6127-6138

Diagnostic accuracy of serum HE4, CA125 and ROMA in patients with ovarian cancer: A meta-analysis

Author keywords

CA125; Human epididymis protein 4; Ovarian cancer; Risk of Ovarian Malignancy Algorithm

Indexed keywords

CA 125 ANTIGEN; HUMAN EPIDIDYMIS PROTEIN 4;

EID: 84904763770     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1811-6     Document Type: Article
Times cited : (114)

References (45)
  • 1
    • 4344704306 scopus 로고    scopus 로고
    • Use of the concomitant serum dosage of CA 125, CA 19-9 and interleukin-6 to detect the presence of endometriosis. Results from a series of reproductive age women undergoing laparoscopic surgery for benign gynaecological conditions
    • DOI 10.1093/humrep/deh312
    • Somigliana E, Vigano P, Tirelli AS, Felicetta I, Torresani E, Vignali M, et al. Use of the concomitant serum dosage of CA 125, CA 19-9 and interleukin-6 to detect the presence of endometriosis. Results from a series of reproductive age women undergoing laparoscopic surgery for benign gynaecological conditions. Hum Reprod. 2004;19(8):1871-6. (Pubitemid 39144638)
    • (2004) Human Reproduction , vol.19 , Issue.8 , pp. 1871-1876
    • Somigliana, E.1    Vigano, P.2    Tirelli, A.S.3    Felicetta, I.4    Torresani, E.5    Vignali, M.6    Di, B.A.M.7
  • 3
    • 80055080310 scopus 로고    scopus 로고
    • Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases
    • Escudero JM, Auge JM, Filella X, Torne A, Pahisa J, Molina R. Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases. Clin Chem. 2011;57(11):1534-44.
    • (2011) Clin Chem , vol.57 , Issue.11 , pp. 1534-1544
    • Escudero, J.M.1    Auge, J.M.2    Filella, X.3    Torne, A.4    Pahisa, J.5    Molina, R.6
  • 4
    • 83055182212 scopus 로고    scopus 로고
    • Human epididymis protein 4 offers superior specificity in the differentiation of benign and malignant adnexal masses in premenopausal women
    • Holcomb K, Vucetic Z, Miller MC, Knapp RC. Human epididymis protein 4 offers superior specificity in the differentiation of benign and malignant adnexal masses in premenopausal women. Am J Obstet Gynecol. 2011;205(4):358.e1- 6.
    • (2011) Am J Obstet Gynecol , vol.205 , Issue.4
    • Holcomb, K.1    Vucetic, Z.2    Miller, M.C.3    Knapp, R.C.4
  • 5
    • 0025826573 scopus 로고
    • A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors
    • Kirchhoff C, Habben I, Ivell R, Krull N. A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. Biol Reprod. 1991;45(2):350-7.
    • (1991) Biol Reprod , vol.45 , Issue.2 , pp. 350-357
    • Kirchhoff, C.1    Habben, I.2    Ivell, R.3    Krull, N.4
  • 6
    • 0034665341 scopus 로고    scopus 로고
    • Identification by cDNA microarray of genes involved in ovarian carcinogenesis
    • Ono K, Tanaka T, Tsunoda T, Kitahara O, Kihara C, Okamoto A, et al. Identification by cDNA microarray of genes involved in ovarian carcinogenesis. Cancer res. 2000;60(18):5007-11.
    • (2000) Cancer Res , vol.60 , Issue.18 , pp. 5007-5011
    • Ono, K.1    Tanaka, T.2    Tsunoda, T.3    Kitahara, O.4    Kihara, C.5    Okamoto, A.6
  • 7
    • 64949192073 scopus 로고    scopus 로고
    • Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    • Huhtinen K, Suvitie P, Hiissa J, Junnila J, Huvila J, Kujari H, et al. Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. Br J Cancer. 2009;100(8):1315-9.
    • (2009) Br J Cancer , vol.100 , Issue.8 , pp. 1315-1319
    • Huhtinen, K.1    Suvitie, P.2    Hiissa, J.3    Junnila, J.4    Huvila, J.5    Kujari, H.6
  • 9
    • 16844374909 scopus 로고    scopus 로고
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    • DOI 10.1158/0008-5472.CAN-04-3924
    • Drapkin R, von Horsten HH, Lin Y, Mok SC, Crum CP, Welch WR, et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer res. 2005;65(6):2162-9. (Pubitemid 40490123)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2162-2169
    • Drapkin, R.1    Von Horsten, H.H.2    Lin, Y.3    Mok, S.C.4    Crum, C.P.5    Welch, W.R.6    Hecht, J.L.7
  • 10
    • 84872856746 scopus 로고    scopus 로고
    • The use of HE4 in the prediction of ovarian cancer in Asian women with a pelvic mass
    • Chan KK, Chen CA, Nam JH, Ochiai K, Wilailak S, Choon AT, et al. The use of HE4 in the prediction of ovarian cancer in Asian women with a pelvic mass. Gynecol Oncol. 2013;128(2):239-44.
    • (2013) Gynecol Oncol , vol.128 , Issue.2 , pp. 239-244
    • Chan, K.K.1    Chen, C.A.2    Nam, J.H.3    Ochiai, K.4    Wilailak, S.5    Choon, A.T.6
  • 11
    • 57649088474 scopus 로고    scopus 로고
    • A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass
    • Moore RG, McMeekin DS, Brown AK, DiSilvestro P, Miller MC, Allard WJ, et al. A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. Gynecol Oncol. 2009;112(1):40-6.
    • (2009) Gynecol Oncol , vol.112 , Issue.1 , pp. 40-46
    • Moore, R.G.1    McMeekin, D.S.2    Brown, A.K.3    DiSilvestro, P.4    Miller, M.C.5    Allard, W.J.6
  • 12
    • 2942700307 scopus 로고    scopus 로고
    • The development of QUADAS: A tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    • Whiting P, Rutjes AW, Reitsma JB, Bossuyt PM, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol. 2003;3:25.
    • (2003) BMC Med Res Methodol , vol.3 , pp. 25
    • Whiting, P.1    Rutjes, A.W.2    Reitsma, J.B.3    Bossuyt, P.M.4    Kleijnen, J.5
  • 14
    • 24944498883 scopus 로고    scopus 로고
    • Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
    • DOI 10.1016/j.jclinepi.2005.02.022, PII S0895435605001629
    • Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol. 2005;58(10):982-90. (Pubitemid 41316441)
    • (2005) Journal of Clinical Epidemiology , vol.58 , Issue.10 , pp. 982-990
    • Reitsma, J.B.1    Glas, A.S.2    Rutjes, A.W.S.3    Scholten, R.J.P.M.4    Bossuyt, P.M.5    Zwinderman, A.H.6
  • 16
    • 0033619529 scopus 로고    scopus 로고
    • Explaining heterogeneity in meta-analysis: A comparison of methods
    • DOI 10.1002/(SICI)1097-0258(19991030)18:20<2693
    • Thompson SG, Sharp SJ. Explaining heterogeneity in meta-analysis: a comparison of methods. Stat Med. 1999;18(20):2693-708. (Pubitemid 29481404)
    • (1999) Statistics in Medicine , vol.18 , Issue.20 , pp. 2693-2708
    • Thompson, S.G.1    Sharp, S.J.2
  • 17
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50(4):1088-101.
    • (1994) Biometrics , vol.50 , Issue.4 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 18
    • 84855675848 scopus 로고    scopus 로고
    • The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses
    • Lenhard M, Stieber P, Hertlein L, Kirschenhofer A, Furst S, Mayr D, et al. The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses. Clin Chem Lab Med : CCLM/ FESCC. 2011;49(21):2081-8.
    • (2011) Clin Chem Lab Med: CCLM/ FESCC , vol.49 , Issue.21 , pp. 2081-2088
    • Lenhard, M.1    Stieber, P.2    Hertlein, L.3    Kirschenhofer, A.4    Furst, S.5    Mayr, D.6
  • 19
    • 84879823068 scopus 로고    scopus 로고
    • The plasma concentration of VEGF, HE4 and CA125 as a new biomarkers panel in different stages and sub-types of epithelial ovarian tumors
    • Lawicki S, Bedkowska GE, Gacuta-Szumarska E, Szmitkowski M. The plasma concentration of VEGF, HE4 and CA125 as a new biomarkers panel in different stages and sub-types of epithelial ovarian tumors. J Ovarian Res. 2013;6(1):45.
    • (2013) J Ovarian Res , vol.6 , Issue.1 , pp. 45
    • Lawicki, S.1    Bedkowska, G.E.2    Gacuta-Szumarska, E.3    Szmitkowski, M.4
  • 20
    • 84879493008 scopus 로고    scopus 로고
    • The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer
    • Anastasi E, Granato T, Falzarano R, Storelli P, Ticino A, Frati L, et al. The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer. J Ovarian Res. 2013;6(1):44.
    • (2013) J Ovarian Res , vol.6 , Issue.1 , pp. 44
    • Anastasi, E.1    Granato, T.2    Falzarano, R.3    Storelli, P.4    Ticino, A.5    Frati, L.6
  • 21
    • 84877585369 scopus 로고    scopus 로고
    • Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age
    • Kondalsamy-Chennakesavan S, Hackethal A, Bowtell D, Obermair A. Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age. Gynecol Oncol. 2013;129(3):467-71.
    • (2013) Gynecol Oncol , vol.129 , Issue.3 , pp. 467-471
    • Kondalsamy-Chennakesavan, S.1    Hackethal, A.2    Bowtell, D.3    Obermair, A.4
  • 22
    • 84876280940 scopus 로고    scopus 로고
    • A comparison between an ultrasound based prediction model (LR2) and the Risk of Ovarian Malignancy Algorithm (ROMA) to assess the risk of malignancy in women with an adnexal mass
    • Kaijser J, Van Gorp T, Van Hoorde K, Van Holsbeke C, Sayasneh A, Vergote I, et al. A comparison between an ultrasound based prediction model (LR2) and the Risk of Ovarian Malignancy Algorithm (ROMA) to assess the risk of malignancy in women with an adnexal mass. Gynecol Oncol. 2013;129(2):377-83.
    • (2013) Gynecol Oncol , vol.129 , Issue.2 , pp. 377-383
    • Kaijser, J.1    Van Gorp, T.2    Van Hoorde, K.3    Van Holsbeke, C.4    Sayasneh, A.5    Vergote, I.6
  • 23
    • 84872588096 scopus 로고    scopus 로고
    • Significance of HE4 estimation in comparison with CA125 in diagnosis of ovarian cancer and assessment of treatment response
    • Hamed EO, Ahmed H, Sedeek OB, Mohammed AM, Abd-Alla AA, Abdel Ghaffar HM. Significance of HE4 estimation in comparison with CA125 in diagnosis of ovarian cancer and assessment of treatment response. Diagn Pathol. 2013;8:11.
    • (2013) Diagn Pathol , vol.8 , pp. 11
    • Hamed, E.O.1    Ahmed, H.2    Sedeek, O.B.3    Mohammed, A.M.4    Abd-Alla, A.A.5    Abdel Ghaffar, H.M.6
  • 24
    • 84872839813 scopus 로고    scopus 로고
    • Comparison of HE4, CA125 and ROMA algorithm in women with a pelvic mass: Correlation with pathological outcome
    • Sandri MT, Bottari F, Franchi D, Boveri S, Candiani M, Ronzoni S, et al. Comparison of HE4, CA125 and ROMA algorithm in women with a pelvic mass: correlation with pathological outcome. Gynecol Oncol. 2012;128(2):233-8.
    • (2012) Gynecol Oncol , vol.128 , Issue.2 , pp. 233-238
    • Sandri, M.T.1    Bottari, F.2    Franchi, D.3    Boveri, S.4    Candiani, M.5    Ronzoni, S.6
  • 26
    • 84867402949 scopus 로고    scopus 로고
    • Evaluation of HE4, CA125, Risk of Ovarian Malignancy Algorithm (ROMA) and risk of malignancy index (RMI) as diagnostic tools of epithelial ovarian cancer in patients with a pelvic mass
    • Karlsen MA, Sandhu N, Hogdall C, Christensen IJ, Nedergaard L, Lundvall L, et al. Evaluation of HE4, CA125, Risk of Ovarian Malignancy Algorithm (ROMA) and risk of malignancy index (RMI) as diagnostic tools of epithelial ovarian cancer in patients with a pelvic mass. Gynecol Oncol. 2012;127(2):379-83.
    • (2012) Gynecol Oncol , vol.127 , Issue.2 , pp. 379-383
    • Karlsen, M.A.1    Sandhu, N.2    Hogdall, C.3    Christensen, I.J.4    Nedergaard, L.5    Lundvall, L.6
  • 27
    • 84863891542 scopus 로고    scopus 로고
    • A comparison of CA125, HE4, risk ovarian malignancy algorithm (ROMA), and risk malignancy index (RMI) for the classification of ovarian masses
    • Anton C, Carvalho FM, Oliveira EI, Maciel GA, Baracat EC, Carvalho JP. A comparison of CA125, HE4, risk ovarian malignancy algorithm (ROMA), and risk malignancy index (RMI) for the classification of ovarian masses. Clin (Sao Paulo). 2012;67(5):437-41.
    • (2012) Clin (Sao Paulo) , vol.67 , Issue.5 , pp. 437-441
    • Anton, C.1    Carvalho, F.M.2    Oliveira, E.I.3    Maciel, G.A.4    Baracat, E.C.5    Carvalho, J.P.6
  • 28
    • 84861494689 scopus 로고    scopus 로고
    • Two-marker combinations for preoperative discrimination of benign and malignant ovarian masses
    • Freydanck MK, Laubender RP, Rack B, Schuhmacher L, Jeschke U, Scholz C. Two-marker combinations for preoperative discrimination of benign and malignant ovarian masses. Anticancer Res. 2012;32(5):2003-8.
    • (2012) Anticancer Res , vol.32 , Issue.5 , pp. 2003-2008
    • Freydanck, M.K.1    Laubender, R.P.2    Rack, B.3    Schuhmacher, L.4    Jeschke, U.5    Scholz, C.6
  • 29
    • 84863607263 scopus 로고    scopus 로고
    • Serum HE4 as a useful biomarker in discriminating ovarian cancer from benign pelvic disease
    • Zheng H, Gao Y. Serum HE4 as a useful biomarker in discriminating ovarian cancer from benign pelvic disease. Int J Gynecol Cancer. 2012;22(6):1000-5.
    • (2012) Int J Gynecol Cancer , vol.22 , Issue.6 , pp. 1000-1005
    • Zheng, H.1    Gao, Y.2
  • 30
    • 84858062503 scopus 로고    scopus 로고
    • The utility of human epididymal protein 4, cancer antigen 125, and risk for malignancy algorithm in ovarian cancer and endometriosis
    • Kadija S, Stefanovic A, Jeremic K, Radojevic MM, Nikolic L, Markovic I, et al. The utility of human epididymal protein 4, cancer antigen 125, and risk for malignancy algorithm in ovarian cancer and endometriosis. Int J Gynecol Cancer. 2012;22(2):238-44.
    • (2012) Int J Gynecol Cancer , vol.22 , Issue.2 , pp. 238-244
    • Kadija, S.1    Stefanovic, A.2    Jeremic, K.3    Radojevic, M.M.4    Nikolic, L.5    Markovic, I.6
  • 31
    • 83055178119 scopus 로고    scopus 로고
    • Serum human epididymis protein 4 and risk for ovarian malignancy algorithm as new diagnostic and prognostic tools for epithelial ovarian cancer management
    • Bandiera E, Romani C, Specchia C, Zanotti L, Galli C, Ruggeri G, et al. Serum human epididymis protein 4 and risk for ovarian malignancy algorithm as new diagnostic and prognostic tools for epithelial ovarian cancer management. Cancer Epidemiol Biomarkers Prev. 2011;20(12):2496-506.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , Issue.12 , pp. 2496-2506
    • Bandiera, E.1    Romani, C.2    Specchia, C.3    Zanotti, L.4    Galli, C.5    Ruggeri, G.6
  • 32
    • 85027944989 scopus 로고    scopus 로고
    • HE4 a novel tumour marker for ovarian cancer: Comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases
    • Molina R, Escudero JM, Auge JM, Filella X, Foj L, Torne A, et al. HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases. Tumour Biol : J Int Soc for Oncodevelopmental Biol Med. 2011;32(6):1087-95.
    • (2011) Tumour Biol: J Int Soc for Oncodevelopmental Biol Med , vol.32 , Issue.6 , pp. 1087-1095
    • Molina, R.1    Escudero, J.M.2    Auge, J.M.3    Filella, X.4    Foj, L.5    Torne, A.6
  • 33
    • 79961056124 scopus 로고    scopus 로고
    • Evaluation of the diagnostic accuracy of the Risk of Ovarian Malignancy Algorithm in women with a pelvic mass
    • Moore RG, Miller MC, Disilvestro P, Landrum LM, Gajewski W, Ball JJ, et al. Evaluation of the diagnostic accuracy of the Risk of Ovarian Malignancy Algorithm in women with a pelvic mass. Obstet Gynecol. 2011;118(2 Pt 1):280-8.
    • (2011) Obstet Gynecol , vol.118 , Issue.2 PART 1 , pp. 280-288
    • Moore, R.G.1    Miller, M.C.2    Disilvestro, P.3    Landrum, L.M.4    Gajewski, W.5    Ball, J.J.6
  • 34
    • 79956310260 scopus 로고    scopus 로고
    • HE4 and epithelial ovarian cancer: Comparison and clinical evaluation of two immunoassays and a combination algorithm
    • Ruggeri G, Bandiera E, Zanotti L, Belloli S, Ravaggi A, Romani C, et al. HE4 and epithelial ovarian cancer: comparison and clinical evaluation of two immunoassays and a combination algorithm. Clin Chim Acta. 2011;412(15-16):1447- 53.
    • (2011) Clin Chim Acta , vol.412 , Issue.15-16 , pp. 1447-1453
    • Ruggeri, G.1    Bandiera, E.2    Zanotti, L.3    Belloli, S.4    Ravaggi, A.5    Romani, C.6
  • 35
    • 83655186047 scopus 로고    scopus 로고
    • Reference ranges for HE4 and CA125 in a large Asian population by automated assays and diagnostic performances for ovarian cancer
    • Park Y, Kim Y, Lee EY, Lee JH, Kim HS. Reference ranges for HE4 and CA125 in a large Asian population by automated assays and diagnostic performances for ovarian cancer. Int J Cancer. 2011;130(5):1136-44.
    • (2011) Int J Cancer , vol.130 , Issue.5 , pp. 1136-1144
    • Park, Y.1    Kim, Y.2    Lee, E.Y.3    Lee, J.H.4    Kim, H.S.5
  • 36
    • 79957504875 scopus 로고    scopus 로고
    • No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting
    • Jacob F, Meier M, Caduff R, Goldstein D, Pochechueva T, Hacker N, et al. No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting. Gynecol Oncol. 2011;121(3):487-91.
    • (2011) Gynecol Oncol , vol.121 , Issue.3 , pp. 487-491
    • Jacob, F.1    Meier, M.2    Caduff, R.3    Goldstein, D.4    Pochechueva, T.5    Hacker, N.6
  • 37
    • 79952801158 scopus 로고    scopus 로고
    • Evaluation of the accuracy of serum human epididymis protein 4 in combination with CA125 for detecting ovarian cancer: A prospective case-control study in a Korean population
    • Kim YM, Whang DH, Park J, Kim SH, Lee SW, Park HA, et al. Evaluation of the accuracy of serum human epididymis protein 4 in combination with CA125 for detecting ovarian cancer: a prospective case-control study in a Korean population. Clin Chem Lab Med. 2011;49(3):527-34.
    • (2011) Clin Chem Lab Med , vol.49 , Issue.3 , pp. 527-534
    • Kim, Y.M.1    Whang, D.H.2    Park, J.3    Kim, S.H.4    Lee, S.W.5    Park, H.A.6
  • 38
    • 79952280663 scopus 로고    scopus 로고
    • HE4 and CA125 as a diagnostic test in ovarian cancer: Prospective validation of the Risk of Ovarian Malignancy Algorithm
    • Van Gorp T, Cadron I, Despierre E, Daemen A, Leunen K, Amant F, et al. HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm. Br J Cancer. 2011;104(5):863-70.
    • (2011) Br J Cancer , vol.104 , Issue.5 , pp. 863-870
    • Van Gorp, T.1    Cadron, I.2    Despierre, E.3    Daemen, A.4    Leunen, K.5    Amant, F.6
  • 39
    • 79952784426 scopus 로고    scopus 로고
    • The ROMA (Risk of Ovarian Malignancy Algorithm) for estimating the risk of epithelial ovarian cancer in women presenting with pelvic mass: Is it really useful?
    • Montagnana M, Danese E, Ruzzenente O, Bresciani V, Nuzzo T, Gelati M, et al. The ROMA (Risk of Ovarian Malignancy Algorithm) for estimating the risk of epithelial ovarian cancer in women presenting with pelvic mass: is it really useful? Clin Chem Lab Med : CCLM / FESCC. 2011;49(3):521-5.
    • (2011) Clin Chem Lab Med: CCLM / FESCC , vol.49 , Issue.3 , pp. 521-525
    • Montagnana, M.1    Danese, E.2    Ruzzenente, O.3    Bresciani, V.4    Nuzzo, T.5    Gelati, M.6
  • 40
    • 77955834079 scopus 로고    scopus 로고
    • HE4 and mesothelin: Novel biomarkers of ovarian carcinoma in patients with pelvic masses
    • Abdel-Azeez HA, Labib HA, Sharaf SM, Refai AN. HE4 and mesothelin: novel biomarkers of ovarian carcinoma in patients with pelvic masses. Asian Pac J Cancer Prev. 2010;11(1):111-6.
    • (2010) Asian Pac J Cancer Prev , vol.11 , Issue.1 , pp. 111-116
    • Abdel-Azeez, H.A.1    Labib, H.A.2    Sharaf, S.M.3    Refai, A.N.4
  • 42
    • 77951976918 scopus 로고    scopus 로고
    • Serum biomarker panels for the discrimination of benign from malignant cases in patients with an adnexal mass
    • Nolen B, Velikokhatnaya L, Marrangoni A, De Geest K, Lomakin A, Bast Jr RC, et al. Serum biomarker panels for the discrimination of benign from malignant cases in patients with an adnexal mass. Gynecol Oncol. 2010;117(3):440-5.
    • (2010) Gynecol Oncol , vol.117 , Issue.3 , pp. 440-445
    • Nolen, B.1    Velikokhatnaya, L.2    Marrangoni, A.3    De Geest, K.4    Lomakin, A.5    Bast Jr., R.C.6
  • 43
    • 66549097456 scopus 로고    scopus 로고
    • Influence of ovarian cancer risk status on the diagnostic performance of the serum biomarkers mesothelin, HE4, and CA125
    • Shah CA, Lowe KA, Paley P, Wallace E, Anderson GL, McIntosh MW, et al. Influence of ovarian cancer risk status on the diagnostic performance of the serum biomarkers mesothelin, HE4, and CA125. Cancer Epidemiol Biomarkers Prev. 2009;18(5):1365-72.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.5 , pp. 1365-1372
    • Shah, C.A.1    Lowe, K.A.2    Paley, P.3    Wallace, E.4    Anderson, G.L.5    McIntosh, M.W.6
  • 45
    • 84884192357 scopus 로고    scopus 로고
    • Symptoms, CA125 and HE4 for the preoperative prediction of ovarian malignancy in Brazilian women with ovarian masses
    • Pitta Dda R, Sarian LO, Barreta A, Campos EA, Andrade LL, Fachini AM, et al. Symptoms, CA125 and HE4 for the preoperative prediction of ovarian malignancy in Brazilian women with ovarian masses. BMC Cancer. 2013;13:423.
    • (2013) BMC Cancer , vol.13 , pp. 423
    • Pitta, Dda.R.1    Sarian, L.O.2    Barreta, A.3    Campos, E.A.4    Andrade, L.L.5    Fachini, A.M.6


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