Effect of tirasemtiv, a selective activator of the fast skeletal muscle troponin complex, in patients with peripheral artery disease

Vascular Medicine (United Kingdom)

Volumn 19, Issue 4, 2014, Pages 297-306

  Bauer, Timothy A ^a,d   Wolff, Andrew A ^b   Hirsch, Alan T ^c   Meng, Lisa L ^b   Rogers, Kevin ^d   Malik, Fady I ^b   Hiatt, William R ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b Cytokinetics Inc   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

6 minute walk; claudication; heel raise test; peripheral artery disease; tirasemtiv

Indexed keywords

CREATINE KINASE; FAST SKELETAL MUSCLE TROPONIN COMPLEX; PLACEBO; TIRASEMTIV; TROPONIN; TROPONIN I; UNCLASSIFIED DRUG;

ADULT; ANKLE BRACHIAL INDEX; AREA UNDER THE CURVE; ARTICLE; CLAUDICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIZZINESS; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ECG ABNORMALITY; EUPHORIA; FATIGUE; FEMALE; FOLLOW UP; GAIT DISORDER; GASTROCNEMIUS MUSCLE; HEEL RAISE TEST; HUMAN; LEG DISEASE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MORNING DOSAGE; MUSCLE FATIGUE; MUSCLE FUNCTION; MUSCULOSKELETAL SYSTEM EXAMINATION; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SKELETAL MUSCLE; STABLE CALF CLAUDICATION; TIME TO MAXIMUM PLASMA CONCENTRATION; WALKING;

EID: 84904739237     PISSN: 1358863X     EISSN: 14770377     Source Type: Journal    
DOI: 10.1177/1358863X14534516     Document Type: Article

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