Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation

Virology

Volumn 464-465, Issue 1, 2014, Pages 87-97

  Ogram, Sushma A ^a   Boone, Christopher D ^a   McKenna, Robert ^a   Flanegan, James B ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

( ) strand RNA; Amiloride; Coxsackievirus B3 (CVB3); Poliovirus (PV); RNA replication complex; VPg; VPg uridylylation

Indexed keywords

AMILORIDE; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; VPG PROTEIN; ANTIVIRUS AGENT; DNA DIRECTED RNA POLYMERASE;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPUTER MODEL; CONTROLLED STUDY; COXSACKIE VIRUS B3; HUMAN; HUMAN CELL; NONHUMAN; POLIOMYELITIS VIRUS 1; PRIORITY JOURNAL; PROTEIN MODIFICATION; RNA REPLICATION; RNA SYNTHESIS; RNA TRANSLATION; URIDYLATION; VIRUS INHIBITION; CHEMICAL STRUCTURE; CHEMISTRY; COXSACKIE VIRUS INFECTION; DOWN REGULATION; DRUG EFFECTS; ENTEROVIRUS; GENETICS; METABOLISM; PHYSIOLOGY; POLIOMYELITIS; POLIOMYELITIS VIRUS; PROTEIN PROCESSING; VIROLOGY; VIRUS REPLICATION;

AMILORIDE; ANTIVIRAL AGENTS; COXSACKIEVIRUS INFECTIONS; DNA-DIRECTED RNA POLYMERASES; DOWN-REGULATION; ENTEROVIRUS; HUMANS; MODELS, MOLECULAR; POLIOMYELITIS; POLIOVIRUS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, VIRAL; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84904725508     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.06.025     Document Type: Article

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