Hormonogenic donor Tyr2522 of bovine thyroglobulin. Insight into preferential T3 formation at thyroglobulin carboxyl terminus at low iodination level

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 488-493

  Cetrangolo, Giovanni Paolo ^a   Arcaro, Alessia ^a   Lepore, Alessio ^b   Graf, Maria ^b   Mamone, Gianfranco ^c   Ferranti, Pasquale ^b   Palumbo, Giuseppe ^b   Gentile, Fabrizio ^a  

^a UNIVERSITY OF MOLISE   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CNR   (Italy)

Author keywords

Dehydroalanine; Donor tyrosine; Hormonogenic tyrosine; Mass spectrometry; Thyroglobulin; Thyroid hormone synthesis

Indexed keywords

DEHYDROALANINE; DIIODOTYROSINE; IODOTYROSINE; LIOTHYRONINE; THYROGLOBULIN; TYROSINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; IODINATION; MOLECULAR WEIGHT; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THYROID HORMONE SYNTHESIS; TIME OF FLIGHT MASS SPECTROMETRY;

BOVINAE;

DEHYDROALANINE; DONOR TYROSINE; HORMONOGENIC TYROSINE; MASS SPECTROMETRY; THYROGLOBULIN; THYROID HORMONE SYNTHESIS;

ANIMALS; BINDING SITES; CATTLE; IODINE; STRUCTURE-ACTIVITY RELATIONSHIP; THYROGLOBULIN; TRIIODOTHYRONINE; TYROSINE;

EID: 84904722584     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.144     Document Type: Article

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