메뉴 건너뛰기




Volumn 35, Issue 6, 2014, Pages 5095-5100

Erythropoietin-stimulating agents and clinical outcomes in metastatic breast cancer patients with chemotherapy-induced anemia: A closed debate?

Author keywords

Breast cancer patients; Chemotherapy induced anemia; Erythropoietin stimulating agents

Indexed keywords

ANTIANEMIC AGENT; HEMOGLOBIN;

EID: 84904718819     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1730-6     Document Type: Review
Times cited : (10)

References (43)
  • 2
    • 0033530262 scopus 로고    scopus 로고
    • Chemotherapy-induced anemia in adults: Incidence and treatment
    • Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst. 1999;91(19):1616-34. (Pubitemid 29479929)
    • (1999) Journal of the National Cancer Institute , vol.91 , Issue.19 , pp. 1616-1634
    • Groopman, J.E.1    Itri, L.M.2
  • 3
    • 0034254503 scopus 로고    scopus 로고
    • Anaemia in cancer: Pathophysiology and treatment
    • DOI 10.1053/ctrv.2000.0181
    • Mercadante S, Gebbia V, Marrazzo A, Filosto S. Anaemia in cancer: pathophysiology and treatment. Cancer Treat Rev. 2000;26(4):303-11. doi:10.1053/ctrv.2000.0181. (Pubitemid 30604041)
    • (2000) Cancer Treatment Reviews , vol.26 , Issue.4 , pp. 303-311
    • Mercadante, S.1    Gebbia, V.2    Marrazzo, A.3    Filosto, S.4
  • 4
    • 71749091026 scopus 로고    scopus 로고
    • Incidence and clinical impact of chemotherapy induced myelotoxicity in cancer patients: An observational retrospective survey
    • doi:10.1016/j.critrevonc.2009.03.004
    • Repetto L. Incidence and clinical impact of chemotherapy induced myelotoxicity in cancer patients: an observational retrospective survey. Crit Rev Oncol Hematol. 2009;72(2):170-9. doi:10.1016/j.critrevonc.2009.03.004.
    • (2009) Crit Rev Oncol Hematol , vol.72 , Issue.2 , pp. 170-179
    • Repetto, L.1
  • 5
    • 54949106168 scopus 로고    scopus 로고
    • Anaemia and cancer treatment: A conceptual change
    • Khan FA, Shukla AN, Joshi SC. Anaemia and cancer treatment: a conceptual change. Singapore Med J. 2008;49(10):759-64.
    • (2008) Singapore Med J , vol.49 , Issue.10 , pp. 759-764
    • Khan, F.A.1    Shukla, A.N.2    Joshi, S.C.3
  • 6
    • 67650717647 scopus 로고    scopus 로고
    • Erythropoietin in cancer patients
    • doi:10.1146/annurev.med.60.050307.110718
    • Glaspy JA. Erythropoietin in cancer patients. Annu Rev Med. 2009;60:181-92. doi:10.1146/annurev.med.60.050307.110718.
    • (2009) Annu Rev Med , vol.60 , pp. 181-192
    • Glaspy, J.A.1
  • 7
    • 0041976976 scopus 로고    scopus 로고
    • Breast cancer trial with erythropoietin terminated unexpectedly
    • DOI 10.1016/S1470-2045(03)01163-X
    • Leyland-Jones B. Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol. 2003;4(8):459-60. (Pubitemid 37009952)
    • (2003) Lancet Oncology , vol.4 , Issue.8 , pp. 459-460
    • Leyland-Jones, B.1
  • 9
    • 39149121539 scopus 로고    scopus 로고
    • Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracyclineand/or taxane-based chemotherapy: Results of the Breast Cancer - Anemia and the Value of Erythropoietin (BRAVE) study
    • DOI 10.1200/JCO.2007.11.5378
    • Aapro M, Leonard RC, Barnadas A, Marangolo M, Untch M, Malamos N, et al. Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline- and/or taxane-based chemotherapy: results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study. J Clin Oncol. 2008;26(4):592-8. doi:10.1200/JCO.2007.11.5378. (Pubitemid 351264353)
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.4 , pp. 592-598
    • Aapro, M.1    Leonard, R.C.2    Barnadas, A.3    Marangolo, M.4    Untch, M.5    Malamos, N.6    Mayordomo, J.7    Reichert, D.8    Pedrini, J.L.9    Ukarma, L.10    Scherhag, A.11    Burger, H.-U.12
  • 10
    • 33846339172 scopus 로고    scopus 로고
    • EORTC guidelines for the use of erythropoietic proteins in anaemic patients with cancer: 2006 update
    • DOI 10.1016/j.ejca.2006.10.014, PII S0959804906009609
    • Bokemeyer C, Aapro MS, Courdi A, Foubert J, Link H, Osterborg A, et al. EORTC guidelines for the use of erythropoietic proteins in anaemic patients with cancer: 2006 update. Eur J Cancer. 2007;43(2):258-70. doi:10.1016/j.ejca.2006. 10.014. (Pubitemid 46127840)
    • (2007) European Journal of Cancer , vol.43 , Issue.2 , pp. 258-270
    • Bokemeyer, C.1    Aapro, M.S.2    Courdi, A.3    Foubert, J.4    Link, H.5    Osterborg, A.6    Repetto, L.7    Soubeyran, P.8
  • 11
    • 0242721510 scopus 로고    scopus 로고
    • Erythropoietin as a Critical Component of Breast Cancer Therapy: Survival, Synergistic, and Cognitive Applications
    • Leyland-Jones B, O'Shaughnessy JA. Erythropoietin as a critical component of breast cancer therapy: survival, synergistic, and cognitive applications. Semin Oncol. 2003;30(5 Suppl 16):174-84. (Pubitemid 37433409)
    • (2003) Seminars in Oncology , vol.30 , Issue.5 SUPPL. 16 , pp. 174-184
    • Leyland-Jones, B.1    O'Shaughnessy, J.A.2
  • 12
    • 70049098312 scopus 로고    scopus 로고
    • Erythropoietin or Darbepoetin for patients with cancer-meta-analysis based on individual patient data
    • doi:10.1002/14651858.CD007303.pub2
    • Bohlius J, Schmidlin K, Brillant C, Schwarzer G, Trelle S, Seidenfeld J, et al. Erythropoietin or Darbepoetin for patients with cancer-meta-analysis based on individual patient data. Cochrane Database Syst Rev. 2009;3, CD007303. doi:10.1002/14651858.CD007303.pub2.
    • (2009) Cochrane Database Syst Rev , vol.3
    • Bohlius, J.1    Schmidlin, K.2    Brillant, C.3    Schwarzer, G.4    Trelle, S.5    Seidenfeld, J.6
  • 18
    • 0021193823 scopus 로고
    • Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five-drug chemotherapy regimen. A study of 159 patients
    • DOI 10.1002/1097-0142(19841001)54:7<1264::AID-CNCR
    • Goodnough LT, Saito H, Manni A, Jones PK, Pearson OH. Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five-drug chemotherapy regimen. A study of 159 patients. Cancer. 1984;54(7):1264-8. (Pubitemid 14003521)
    • (1984) Cancer , vol.54 , Issue.7 , pp. 1264-1268
    • Goodnough, L.T.1    Saito, H.2    Manni, A.3
  • 19
    • 54049108538 scopus 로고    scopus 로고
    • Venous thromboembolic events and erythropoiesis-stimulating agents: An update
    • doi:10.1634/theoncologist.13-S3-11
    • Dicato M. Venous thromboembolic events and erythropoiesis-stimulating agents: an update. Oncologist. 2008;13 Suppl 3:11-5. doi:10.1634/theoncologist. 13-S3-11.
    • (2008) Oncologist , vol.13 , Issue.SUPPL. 3 , pp. 11-15
    • Dicato, M.1
  • 21
    • 24944454286 scopus 로고    scopus 로고
    • Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: A survival study
    • doi:10.1200/JCO.2005.06.150
    • Leyland-Jones B, Semiglazov V, Pawlicki M, Pienkowski T, Tjulandin S, Manikhas G, et al. Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol. 2005;23(25):5960-72. doi:10.1200/JCO.2005.06.150.
    • (2005) J Clin Oncol , vol.23 , Issue.25 , pp. 5960-5972
    • Leyland-Jones, B.1    Semiglazov, V.2    Pawlicki, M.3    Pienkowski, T.4    Tjulandin, S.5    Manikhas, G.6
  • 23
    • 84880551960 scopus 로고    scopus 로고
    • Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer: Randomized clinical trial
    • doi:10.1093/jnci/djt145
    • Moebus V, Jackisch C, Schneeweiss A, Huober J, Lueck HJ, du Bois A, et al. Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer: randomized clinical trial. J Natl Cancer Inst. 2013;105(14):1018-26. doi:10.1093/jnci/djt145.
    • (2013) J Natl Cancer Inst , vol.105 , Issue.14 , pp. 1018-1026
    • Moebus, V.1    Jackisch, C.2    Schneeweiss, A.3    Huober, J.4    Lueck, H.J.5    Du Bois, A.6
  • 24
    • 18744401355 scopus 로고    scopus 로고
    • Feasibility of quantifying the effects of epoetin alfa therapy on cognitive function in women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy
    • O'Shaughnessy JA, Vukelja SJ, Holmes FA, Savin M, Jones M, Royall D, et al. Feasibility of quantifying the effects of epoetin alfa therapy on cognitive function in women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy. Clin Breast Cancer. 2005;5(6):439-46.
    • (2005) Clin Breast Cancer , vol.5 , Issue.6 , pp. 439-446
    • O'Shaughnessy, J.A.1    Vukelja, S.J.2    Holmes, F.A.3    Savin, M.4    Jones, M.5    Royall, D.6
  • 25
    • 80052401850 scopus 로고    scopus 로고
    • PREPARE trial: A randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer - Outcome on prognosis
    • doi:10.1093/annonc/mdq713
    • Untch M, von Minckwitz G, Konecny GE, Conrad U, Fett W, Kurzeder C, et al. PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer - outcome on prognosis. Ann Oncol. 2011;22(9):1999-2006. doi:10.1093/annonc/mdq713.
    • (2011) Ann Oncol , vol.22 , Issue.9 , pp. 1999-2006
    • Untch, M.1    Von Minckwitz, G.2    Konecny, G.E.3    Conrad, U.4    Fett, W.5    Kurzeder, C.6
  • 26
    • 18444398661 scopus 로고    scopus 로고
    • Weekly epoetin alfa maintains hemoglobin, improves quality of life, and reduces transfusion in breast cancer patients receiving chemotherapy
    • DOI 10.1200/JCO.2004.12.027
    • Chang J, Couture F, Young S, McWatters KL, Lau CY. Weekly epoetin alfa maintains hemoglobin, improves quality of life, and reduces transfusion in breast cancer patients receiving chemotherapy. J Clin Oncol. 2005;23(12):2597-605. doi:10.1200/JCO.2004.12.027. (Pubitemid 46179448)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.12 , pp. 2597-2605
    • Chang, J.1    Couture, F.2    Young, S.3    McWatters, K.-L.4    Lau, C.Y.5
  • 27
    • 77957767662 scopus 로고    scopus 로고
    • Epoetin alfa improves anemia and anemia-related, patient-reported outcomes in patients with breast cancer receiving myelotoxic chemotherapy: Results of a European, multicenter, randomized, controlled trial
    • doi:10.1634/theoncologist.2009-0279
    • Pronzato P, Cortesi E, van der Rijt CC, Bols A, Moreno-Nogueira JA, de Oliveira CF, et al. Epoetin alfa improves anemia and anemia-related, patient-reported outcomes in patients with breast cancer receiving myelotoxic chemotherapy: results of a European, multicenter, randomized, controlled trial. Oncologist. 2010;15(9):935-43. doi:10.1634/theoncologist.2009-0279.
    • (2010) Oncologist , vol.15 , Issue.9 , pp. 935-943
    • Pronzato, P.1    Cortesi, E.2    Van Der Rijt, C.C.3    Bols, A.4    Moreno-Nogueira, J.A.5    De Oliveira, C.F.6
  • 29
    • 84859218749 scopus 로고    scopus 로고
    • Effects of erythropoietin receptors and erythropoiesis-stimulating agents on disease progression in cancer
    • doi:10.1038/bjc.2012.42
    • Aapro M, Jelkmann W, Constantinescu SN, Leyland-Jones B. Effects of erythropoietin receptors and erythropoiesis-stimulating agents on disease progression in cancer. Br J Cancer. 2012;106(7):1249-58. doi:10.1038/bjc.2012. 42.
    • (2012) Br J Cancer , vol.106 , Issue.7 , pp. 1249-1258
    • Aapro, M.1    Jelkmann, W.2    Constantinescu, S.N.3    Leyland-Jones, B.4
  • 30
    • 50349088773 scopus 로고    scopus 로고
    • Continuing reassessment of the risks of erythropoiesis-stimulating agents in patients with cancer
    • doi:10.1158/1078-0432.CCR-07-1872
    • Juneja V, Keegan P, Gootenberg JE, Rothmann MD, Shen YL, Lee KY, et al. Continuing reassessment of the risks of erythropoiesis-stimulating agents in patients with cancer. Clin Cancer Res. 2008;14(11):3242-7. doi:10.1158/1078- 0432.CCR-07-1872.
    • (2008) Clin Cancer Res , vol.14 , Issue.11 , pp. 3242-3247
    • Juneja, V.1    Keegan, P.2    Gootenberg, J.E.3    Rothmann, M.D.4    Shen, Y.L.5    Lee, K.Y.6
  • 31
    • 34248195397 scopus 로고    scopus 로고
    • Do erythropoietin receptors on cancer cells explain unexpected clinical findings? [5]
    • DOI 10.1200/JCO.2006.09.9713
    • Clavo B. Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol. 2007;25(11):1447-8. doi:10.1200/JCO.2006.09. 9713. (Pubitemid 46706900)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.11 , pp. 1447-1448
    • Clavo, B.1
  • 32
    • 31444447968 scopus 로고    scopus 로고
    • Patients previously transfused or treated with epoetin alfa at low baseline hemoglobin are at higher risk for subsequent transfusion: An integrated analysis of the Canadian experience
    • DOI 10.1634/theoncologist.11-1-73
    • Quirt I, Kovacs M, Couture F, Turner AR, Noble M, Burkes R, et al. Patients previously transfused or treated with epoetin alfa at low baseline hemoglobin are at higher risk for subsequent transfusion: an integrated analysis of the Canadian experience. Oncologist. 2006;11(1):73-82. doi:10.1634/ theoncologist.11-1-73. (Pubitemid 43152689)
    • (2006) Oncologist , vol.11 , Issue.1 , pp. 73-82
    • Quirt, I.1    Kovacs, M.2    Couture, F.3    Turner, A.R.4    Noble, M.5    Burkes, R.6    Dolan, S.7    Plante, R.K.8    Lau, C.Y.9    Chang, J.10
  • 33
    • 0035366382 scopus 로고    scopus 로고
    • Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: Improvements in hemoglobin and quality of life are similar to three-times-weekly dosing
    • Gabrilove JL, Cleeland CS, Livingston RB, Sarokhan B, Winer E, Einhorn LH. Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times-weekly dosing. J Clin Oncol. 2001;19(11):2875-82. (Pubitemid 32538197)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.11 , pp. 2875-2882
    • Gabrilove, J.L.1    Cleeland, C.S.2    Livingston, R.B.3    Sarokhan, B.4    Winer, E.5    Einhorn, L.H.6
  • 34
    • 80051552235 scopus 로고    scopus 로고
    • Complications associated with erythropoietin-stimulating agents in patients with metastatic breast cancer: A surveillance, epidemiology, and end results-Medicare study
    • doi:10.1002/cncr.25972
    • Chavez-MacGregor M, Zhao H, Fang S, Srokowski TP, Hortobagyi GN, Giordano SH. Complications associated with erythropoietin-stimulating agents in patients with metastatic breast cancer: a surveillance, epidemiology, and end results-Medicare study. Cancer. 2011;117(16):3641-9. doi:10.1002/cncr.25972.
    • (2011) Cancer , vol.117 , Issue.16 , pp. 3641-3649
    • Chavez-MacGregor, M.1    Zhao, H.2    Fang, S.3    Srokowski, T.P.4    Hortobagyi, G.N.5    Giordano, S.H.6
  • 35
    • 80053508260 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in combination with chemotherapy increases breast cancer metastasis in preclinical mouse models
    • doi:10.1158/1078-0432.CCR-10-3298
    • Hedley BD, Chu JE, Ormond DG, Beausoleil MS, Boasie A, Allan AL, et al. Recombinant human erythropoietin in combination with chemotherapy increases breast cancer metastasis in preclinical mouse models. Clin Cancer Res. 2011;17(19):6151-62. doi:10.1158/1078-0432.CCR-10-3298.
    • (2011) Clin Cancer Res , vol.17 , Issue.19 , pp. 6151-6162
    • Hedley, B.D.1    Chu, J.E.2    Ormond, D.G.3    Beausoleil, M.S.4    Boasie, A.5    Allan, A.L.6
  • 36
    • 0036787775 scopus 로고    scopus 로고
    • Use of epoetin in patients with cancer: Evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology
    • Rizzo JD, Lichtin AE, Woolf SH, Seidenfeld J, Bennett CL, Cella D, et al. Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology. J Clin Oncol. 2002;20(19):4083-107.
    • (2002) J Clin Oncol , vol.20 , Issue.19 , pp. 4083-4107
    • Rizzo, J.D.1    Lichtin, A.E.2    Woolf, S.H.3    Seidenfeld, J.4    Bennett, C.L.5    Cella, D.6
  • 37
    • 0001390321 scopus 로고    scopus 로고
    • Recombinant human erythropoietin (rHuEPO) for the treatment of the anemia of cancer
    • Abels RI, Larholt KM, Krantz KD, Bryant EC. Recombinant human erythropoietin (rHuEPO) for the treatment of the anemia of cancer. Oncologist. 1996;1(3):140-50. (Pubitemid 126669230)
    • (1996) Oncologist , vol.1 , Issue.3 , pp. 140-150
    • Abels, R.I.1    Larholt, K.M.2    Krantz, K.D.3    Bryant, E.C.4
  • 38
    • 80052712426 scopus 로고    scopus 로고
    • Physician characteristics and variability of erythropoiesis-stimulating agent use among Medicare patients with cancer
    • doi:10.1200/JCO.2010.34.5462
    • Wright JD, Neugut AI, Wilde ET, Buono DL, Malin J, Tsai WY, et al. Physician characteristics and variability of erythropoiesis-stimulating agent use among Medicare patients with cancer. J Clin Oncol. 2011;29(25):3408-18. doi:10.1200/JCO.2010.34.5462.
    • (2011) J Clin Oncol , vol.29 , Issue.25 , pp. 3408-3418
    • Wright, J.D.1    Neugut, A.I.2    Wilde, E.T.3    Buono, D.L.4    Malin, J.5    Tsai, W.Y.6
  • 39
    • 84865159854 scopus 로고    scopus 로고
    • Hematologic outcomes and blood utilization in cancer patients with chemotherapy-induced anemia (CIA) pre- and post-national coverage determination (NCD): Results from a multicenter chart review
    • doi:10.1007/s00520-011-1318-2
    • Henry DH, Langer CJ, McKenzie RS, Piech CT, Senbetta M, Schulman KL, et al. Hematologic outcomes and blood utilization in cancer patients with chemotherapy-induced anemia (CIA) pre- and post-national coverage determination (NCD): results from a multicenter chart review. Support Care Cancer. 2012;20(9):2089-96. doi:10.1007/s00520-011-1318-2.
    • (2012) Support Care Cancer , vol.20 , Issue.9 , pp. 2089-2096
    • Henry, D.H.1    Langer, C.J.2    McKenzie, R.S.3    Piech, C.T.4    Senbetta, M.5    Schulman, K.L.6
  • 40
    • 84857900559 scopus 로고    scopus 로고
    • Management of anemia in advanced breast and lung cancer patients in daily practice: Results of a French survey
    • doi:10.1007/s12325-011-0093-2
    • Ray-Coquard I, Morere JF, Scotte F, Cals L, Antoine EC. Management of anemia in advanced breast and lung cancer patients in daily practice: results of a French survey. Adv Ther. 2012;29(2):124-33. doi:10.1007/s12325-011-0093-2.
    • (2012) Adv Ther , vol.29 , Issue.2 , pp. 124-133
    • Ray-Coquard, I.1    Morere, J.F.2    Scotte, F.3    Cals, L.4    Antoine, E.C.5
  • 41
    • 27744582735 scopus 로고    scopus 로고
    • Chemotherapy-induced anaemia during adjuvant treatment for breast cancer: Development of a prediction model
    • DOI 10.1016/S1470-2045(05)70394-6, PII S1470204505703946
    • Dranitsaris G, Clemons M, Verma S, Lau C, Vincent M. Chemotherapy-induced anaemia during adjuvant treatment for breast cancer: development of a prediction model. Lancet Oncol. 2005;6(11):856-63. doi:10.1016/S1470-2045(05) 70394-6. (Pubitemid 41614797)
    • (2005) Lancet Oncology , vol.6 , Issue.11 , pp. 856-863
    • Dranitsaris, G.1    Clemons, M.2    Verma, S.3    Lau, C.4    Vincent, M.5
  • 42
    • 84858129582 scopus 로고    scopus 로고
    • Evaluation of cost savings with ferric carboxymaltose in anemia treatment through its impact on erythropoiesis-stimulating agents and blood transfusion: French healthcare payer perspective
    • doi:10.3111/13696998.2011.639823
    • Luporsi E, Mahi L, Morre C, Wernli J, de Pouvourville G, Bugat R. Evaluation of cost savings with ferric carboxymaltose in anemia treatment through its impact on erythropoiesis-stimulating agents and blood transfusion: French healthcare payer perspective. J Med Econ. 2012;15(2):225 -32. doi:10.3111/13696998.2011.639823.
    • (2012) J Med Econ , vol.15 , Issue.2 , pp. 225-232
    • Luporsi, E.1    Mahi, L.2    Morre, C.3    Wernli, J.4    De Pouvourville, G.5    Bugat, R.6
  • 43
    • 64849096679 scopus 로고    scopus 로고
    • Treatment of venous thromboembolismin patients with cancer: Subgroup analysis of the Matisse clinical trials
    • van Doormaal FF, Raskob GE, Davidson BL, Decousus H, Gallus A, Lensing AW, et al. Treatment of venous thromboembolismin patients with cancer: subgroup analysis of the Matisse clinical trials. Thromb Haemost. 2009;101(4):762-9.
    • (2009) Thromb Haemost , vol.101 , Issue.4 , pp. 762-769
    • Van Doormaal, F.F.1    Raskob, G.E.2    Davidson, B.L.3    Decousus, H.4    Gallus, A.5    Lensing, A.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.