Pharmacologic induction of heme oxygenase-1: It is time to take it seriously

Critical Care Medicine

Volumn 42, Issue 8, 2014, Pages 1967-1968

  Li Volti, Giovanni ^a,b   Murabito, Paolo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b Euro Mediterranean Institute of Science and Technology   (Italy)

Author keywords

antioxidants; carbon monoxide; diabetes; heme oxygenase; propofol

Indexed keywords

BILIRUBIN; BILIVERDIN; CARBOHYDRATE; CARBON MONOXIDE; FERRITIN; HEME OXYGENASE 1; IRON; ISOPROSTANE DERIVATIVE; LIPID; NITRIC OXIDE; NUCLEIC ACID; PEROXYNITRITE; PROPOFOL; STAT1 PROTEIN; STAT3 PROTEIN; SUPEROXIDE; ACTIVATING TRANSCRIPTION FACTOR 3;

APOPTOSIS; CLINICAL EVALUATION; DRUG ACETYLATION; EDITORIAL; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MODIFICATION; ENZYME REGULATION; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART MUSCLE INJURY; HUMAN; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PALMITOYLATION; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; UBIQUITINATION; ANIMAL; CARDIOMEGALY; COMPLICATION; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; MALE; METABOLISM;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; CARDIOMEGALY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; HEME OXYGENASE-1; MALE; PROPOFOL;

EID: 84904696786     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000458     Document Type: Editorial

References (13)

1. Sayin MM, Ozatamer O, Taöz R, et al: Propofol attenuates myocardial lipid peroxidation during coronary artery bypass grafting surgery. Br J Anaesth 2002; 89:242-246
2. Stratford N, Murphy P: Antioxidant activity of propofol in blood from anaesthetized patients. Eur J Anaesthesiol 1998; 15:158-160
3. Acquaviva R, Campisi A, Raciti G, et al: Propofol inhibits caspase-3 in astroglial cells: Role of heme oxygenase-1. Curr Neurovasc Res 2005; 2:141-148
4. Xu J, Li H, Irwin MG, et al: Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats. Crit Care Med 2014; 42:e583-e594
5. Barbagallo I, Galvano F, Frigiola A, et al: Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases. Antioxid Redox Signal 2013; 18:507-521
6. Li Volti G, Sorrenti V, Murabito P, et al: Pharmacological induction of heme oxygenase-1 inhibits iNOS and oxidative stress in renal isch-emia-reperfusion injury. Transplant Proc 2007; 39:2986-2991
7. Sacerdoti D, Colombrita C, Ghattas MH, et al: Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in infammation and growth. Cell Mol Biol (Noisy-le-grand) 2005; 51:363-370
8. Abraham NG, Rezzani R, Rodella L, et al: Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes. Am J Physiol Heart Circ Physiol 2004; 287:H2468-H2477
9. Dunn LL, Midwinter RG, Ni J, et al: New insights into intracellular locations and functions of heme oxygenase-1. Antioxid Redox Signal 2014; 20:1723-1742
10. Kinobe R, Ji Y, Nakatsu K: Peroxynitrite-mediated inactivation of heme oxygenases. BMC Pharmacol 2004; 4:26
11. Stein AB, Bolli R, Dawn B, et al: Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium. J Mol Cell Cardiol 2012; 52:228-236
12. Salomone F, Li Volti G, Rosso C, et al: Unconjugated bilirubin, a potent endogenous antioxidant, is decreased in patients with non-alcoholic steatohepatitis and advanced fbrosis. J Gastroenterol Hepatol 2013; 28:1202-1208
13. Barbagallo I, Marrazzo G, Frigiola A, et al: Role of carbon monoxide in vascular diseases. Curr Pharm Biotechnol 2012; 13:787-796