A neurodegenerative vascular burden index and the impact on cognition

Frontiers in Aging Neuroscience

Volumn 6, Issue JUL, 2014, Pages

  Heinzel, Sebastian ^a   Liepelt Scarfone, Inga ^a,b   Roeben, Benjamin ^a   Nasi Kordhishti, Isabella ^a   Suenkel, Ulrike ^a   Wurster, Isabel ^a   Brockmann, Kathrin ^a   Fritsche, Andreas ^c   Niebler, Raphael ^d   Metzger, Florian G ^d   Eschweiler, Gerhard W ^d   Fallgatter, Andreas J ^d   Maetzler, Walter ^a   Berg, Daniela ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Alzheimer's disease; Carotid intima media thickness; CERAD neuropsychological battery; Neurodegeneration; Prodromal marker; Trail making test; T binger evaluation of risk factors for early detection of neurodegeneration (TREND) study; Vascular burden

Indexed keywords

ADULT; AGING; ALZHEIMER DISEASE; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RISK; COGNITION; COHORT ANALYSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; EXECUTIVE FUNCTION; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NERVE DEGENERATION; NEUROPSYCHOLOGICAL TEST; OBESITY; PSYCHOLOGIC TEST; SMOKING; VASCULAR BURDEN INDEX;

EID: 84904685907     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00161     Document Type: Article

References (53)

1. Baldassarre, D., Nyyssonen, K., Rauramaa, R., De Faire, U., Hamsten, A., Smit, A. J., et al. (2010). Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study. Eur. Heart J. 31, 614-622. doi: 10.1093/eurheartj/ehp496
2. Berg, D. (2012). Is pre-motor diagnosis possible? The European experience. Parkinsonism Relat. Disord. 18(Suppl. 1), S195-S198. doi:10.1016/S1353-8020(11)70061-X
3. Bots, M. L., Hoes, A. W., Koudstaal, P. J., Hofman, A., and Grobbee, D. E. (1997). Common carotid intima-media thickness and risk of stroke and myocardial infarction - the Rotterdam study. Circulation 96, 1432-1437. doi:10.1161/01.CIR.96.5.1432
4. Bots, M. L., Hofman, A., De Bruyn, A. M., De Jong, P. T., and Grobbee, D. E. (1993). Isolated systolic hypertension and vessel wall thickness of the carotid artery. The Rotterdam elderly study. Arterioscler. Thromb. 13, 64-69. doi:10.1161/01.ATV.13.1.64
5. Bots, M. L., Hofman, A., Dejong, P. T. V. M., and Grobbee, D. E. (1996). Common carotid intima media thickness as an indicator of atherosclerosis at other sites of the carotid artery - the Rotterdam study. Ann. Epidemiol. 6, 147-153. doi:10.1016/1047-2797(96)00001-4
6. Bowie, C. R., and Harvey, P. D. (2006). Administration and interpretation of the trail making test. Nat. Protoc. 1, 2277-2281. doi:10.1038/nprot.2006.390
7. Breteler, M. M. B. (2000). Vascular risk factors for Alzheimer's disease: an epidemiologic perspective. Neurobiol. Aging 21, 153-160. doi:10.1016/S0197-4580(99)00110-4
8. Cataldo, J. K., Prochaska, J. J., and Glantz, S. A. (2010). Cigarette smoking is a risk factor for Alzheimer's disease: an analysis controlling for tobacco industry affiliation. J. Alzheimers Dis. 19, 465-480. doi:10.3233/JAD-2010-1240
9. Chandler, M. J., Lacritz, L. H., Hynan, L. S., Barnard, H. D., Allen, G., Deschner, M., et al. (2005). A total score for the CERAD neuropsychological battery. Neurology 65, 102-106. doi:10.1212/01.wnl.0000167607.63000.38
10. Chao, L. L., Buckley, S. T., Kornak, J., Schuff, N., Madison, C., Yaffe, K., et al. (2010). ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia. Alzheimer Dis. Assoc. Disord. 24, 19-27. doi:10.1097/WAD.0b013e3181b4f736
11. Corrigan, J. D., and Hinkeldey, N. S. (1987). Relationships between parts A and B of the trail making test. J. Clin. Psychol. 43, 402-409. doi:10.1002/1097-4679(198707)43:4<402::AID-JCLP2270430411>3.0.CO;2-E
12. D'Agostino, R. B. Sr., Vasan, R. S., Pencina, M. J., Wolf, P. A., Cobain, M., Massaro, J. M., et al. (2008). General cardiovascular risk profile for use in primary care: the Framingham heart study. Circulation 117, 743-753. doi:10.1161/CIRCULATIONAHA.107.699579
13. de la Torre, J. C. (2012a). Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia. Cardiovasc. Psychiatry. Neurol. 2012, 367516. doi:10.1155/2012/367516
14. de la Torre, J. C. (2012b). Cerebral hemodynamics and vascular risk factors: setting the stage for Alzheimer's disease. J. Alzheimers Dis. 32, 553-567. doi:10.3233/JAD-2012-120793
15. Den Ruijter, H. M., Peters, S. A. E., Anderson, T. J., Britton, A. R., Dekker, J. M., Eijkemans, M. J., et al. (2012). Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA 308, 796-803. doi:10.1001/jama.2012.9630
16. Ehrensperger, M. M., Berres, M., Taylor, K. I., and Monsch, A. U. (2010). Early detection of Alzheimer's disease with a total score of the German CERAD. J. Int. Neuropsychol. Soc. 16, 910-920. doi:10.1017/S1355617710000822
17. Engelen, L., Ferreira, I., Stehouwer, C. D., Boutouyrie, P., and Laurent, S. (2012). Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors. Eur. Heart J. 34, 2368-2380. doi:10.1093/eurheartj/ehs380
18. Folsom, A. R., Eckfeldt, J. H., Weitzman, S., Ma, J., Chambless, L. E., Barnes, R. W., et al. (1994). Relation of carotid-artery wall thickness to diabetes-mellitus, fasting glucose and insulin, body-size, and physical-activity. Stroke 25, 66-73. doi:10.1161/01.STR.25.1.66
19. Gaenslen, A., Wurster, I., Brockmann, K., Huber, H., Godau, J., Faust, B., et al. (2014). Prodromal features for Parkinson's disease - baseline data from the TREND study. Eur. J. Neurol. 21, 766-772. doi:10.1111/ene.12382
20. Heinzel, S., Metzger, F. G., Ehlis, A. C., Korell, R., Alboji, A., Haeussinger, F. B., et al. (2013). Aging-related cortical reorganization of verbal fluency processing: a functional near-infrared spectroscopy study. Neurobiol. Aging 34, 439-450. doi:10.1016/j.neurobiolaging.2012.05.021
21. Hobert, M. A., Niebler, R., Meyer, S. I., Brockmann, K., Becker, C., Huber, H., et al. (2011). Poor trail making test performance is directly associated with altered dual task prioritization in the elderly - baseline results from the TREND study. PLoS ONE 6:e27831. doi:10.1371/journal.pone.0027831
22. Honig, L. S., Tang, M. X., Albert, S., Costa, R., Luchsinger, J., Manly, J., et al. (2003). Stroke and the risk of Alzheimer disease. Arch. Neurol. 60, 1707-1712. doi:10.1001/archneur.60.12.1707
23. Hort, J., O'brien, J. T., Gainotti, G., Pirttila, T., Popescu, B. O., Rektorova, I., et al. (2010). EFNS guidelines for the diagnosis and management of Alzheimer's disease. Eur. J. Neurol. 17, 1236-1248. doi:10.1111/j.1468-1331.2010.03040.x
24. Hughes, T. M., Kuller, L. H., Barinas-Mitchell, E. J., Mackey, R. H., Mcdade, E. M., Klunk, W. E., et al. (2013). Pulse wave velocity is associated with beta-amyloid deposition in the brains of very elderly adults. Neurology 81, 1711-1718. doi:10.1212/01.wnl.0000435301.64776.37
25. Kilpatrick, E. S., Bloomgarden, Z. T., and Zimmet, P. Z. (2009). International expert committee report on the role of the A1C assay in the diagnosis of diabetes: response to the international expert committee. Diabetes Care 32, e159. doi:10.2337/dc09-1231
26. Kivipelto, M., Ngandu, T., Fratiglioni, L., Viitanen, M., Kareholt, I., Winblad, B., et al. (2005). Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch. Neurol. 62, 1556-1560. doi:10.1001/archneur.62.10.1556
27. Kivipelto, M., and Solomon, A. (2006). Cholesterol as a risk factor for Alzheimer's disease - epidemiological evidence. Acta Neurol. Scand. Suppl. 185, 50-57. doi:10.1111/j.1600-0404.2006.00685.x
28. Kotsis, V. T., Stabouli, S. V., Papamichael, C. M., and Zakopoulos, N. A. (2006). Impact of obesity in intima media thickness of carotid arteries. Obesity (Silver Spring) 14, 1708-1715. doi:10.1038/oby.2006.196
29. Langbaum, J. B., Fleisher, A. S., Chen, K., Ayutyanont, N., Lopera, F., Quiroz, Y. T., et al. (2013). Ushering in the study and treatment of preclinical Alzheimer disease. Nat. Rev. Neurol. 9, 371-381. doi:10.1038/nrneurol.2013.107
30. Li, J., Wang, Y. J., Zhang, M., Xu, Z. Q., Gao, C. Y., Fang, C. Q., et al. (2011). Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease. Neurology 76, 1485-1491. doi:10.1212/WNL.0b013e318217e7a4
31. Lim, Y. Y., Maruff, P., Pietrzak, R. H., Ellis, K. A., Darby, D., Ames, D., et al. (2014). Abeta and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease. Alzheimers Dement. doi:10.1016/j.jalz.2013.11.005
32. Lorenz, M. W., Markus, H. S., Bots, M. L., Rosvall, M., and Sitzer, M. (2007). Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 115, 459-467. doi:10.1161/CIRCULATIONAHA.106.628875
33. Mackinnon, A. D., Jerrard-Dunne, P., Sitzer, M., Buehler, A., Von Kegler, S., and Markus, H. S. (2004). Rates and determinants of site-specific progression of carotid artery intima-media thickness: the carotid atherosclerosis progression study. Stroke 35, 2150-2154. doi:10.1161/01.STR.0000136720.21095.f3
34. Maetzler, W., Langkamp, M., Lerche, S., Godau, J., Brockmann, K., Gaenslen, A., et al. (2012). Lowered serum amyloid-beta1-42 autoantibodies in individuals with lifetime depression. J. Alzheimers Dis. 32, 95-100. doi:10.3233/JAD-2012-120625
35. Mancia, G., De Backer, G., Dominiczak, A., Cifkova, R., Fagard, R., Germano, G., et al. (2007). 2007 Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European society of hypertension (ESH) and of the European society of cardiology (ESC). Eur. Heart J. 28, 1462-1536. doi:10.1093/eurheartj/ehm236
36. Moghekar, A., Li, S., Lu, Y., Li, M., Wang, M. C., Albert, M., et al. (2013). CSF biomarker changes precede symptom onset of mild cognitive impairment. Neurology 81, 1753-1758. doi:10.1212/01.wnl.0000435558.98447.17
37. Morris, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., Van Belle, G., Fillenbaum, G., et al. (1989). The consortium to establish a registry for Alzheimer's disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 39, 1159-1165. doi:10.1212/WNL.39.9.1159
38. Niu, L. L., Zhang, Y. L., Qian, M., Meng, L., Xiao, Y., Wang, Y. Y., et al. (2013). Impact of multiple cardiovascular risk factors on carotid intima-media thickness and elasticity. PLoS ONE 8:e67809. doi:10.1371/journal.pone.0067809
39. O'Leary, D. H., Polak, J. F., Kronmal, R. A., Savage, P. J., Borhani, N. O., Kittner, S. J., et al. (1996). Thickening of the carotid wall. A marker for atherosclerosis in the elderly? Cardiovascular Health Study Collaborative Research Group. Stroke 27, 224-231. doi:10.1161/01.STR.27.2.224
40. Olesen, J. B., Lip, G. Y., Hansen, M. L., Hansen, P. R., Tolstrup, J. S., Lindhardsen, J., et al. (2011). Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ 342, d124. doi:10.1136/bmj.d124
41. Purnell, C., Gao, S., Callahan, C. M., and Hendrie, H. C. (2009). Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literature. Alzheimer Dis. Assoc. Disord. 23, 1-10. doi:10.1097/WAD.0b013e318187541c
42. Rundek, T., Blanton, S. H., Bartels, S., Dong, C., Raval, A., Demmer, R. T., et al. (2013). Traditional risk factors are not major contributors to the variance in carotid intima-media thickness. Stroke 44, 2101-2108. doi:10.1161/STROKEAHA.111.000745
43. Salonen, R., and Salonen, J. T. (1991). Determinants of carotid intima-media thickness: a population-based ultrasonography study in eastern Finnish men. J. Intern. Med. 229, 225-231. doi:10.1111/j.1365-2796.1991.tb00336.x
44. Sanchez-Cubillo, I., Perianez, J. A., Adrover-Roig, D., Rodriguez-Sanchez, J. M., Rios-Lago, M., Tirapu, J., et al. (2009). Construct validity of the trail making test: role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. J. Int. Neuropsychol. Soc. 15, 438-450. doi:10.1017/S1355617709090626
45. Smith, C. D., Andersen, A. H., Gold, B. T., and Neuroimaging, A. D. (2012). Structural brain alterations before mild cognitive impairment in ADNI: validation of volume loss in a predefined antero-temporal region. J. Alzheimers Dis. 31, S49-S58. doi:10.3233/Jad-2012-120157
46. Stein, J. H., Fraizer, M. C., Aeschlimann, S. E., Nelson-Worel, J., Mcbride, P. E., and Douglas, P. S. (2004). Vascular age: integrating carotid intima-media thickness measurements with global coronary risk assessment. Clin. Cardiol. 27, 388-392. doi:10.1002/clc.4960270704
47. Touboul, P. J., Hennerici, M. G., Meairs, S., Adams, H., Amarenco, P., Bornstein, N., et al. (2012). Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European stroke conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011. Cerebrovasc. Dis. 34, 290-296. doi:10.1159/000343145
48. Urbina, E. M., Srinivasan, S. R., Tang, R., Bond, M. G., Kieltyka, L., and Berenson, G. S. (2002). Impact of multiple coronary risk factors on the intima-media thickness of different segments of carotid artery in healthy young adults (the Bogalusa heart study). Am. J. Cardiol. 90, 953-958. doi:10.1016/S0002-9149(02)02660-7
49. van den Oord, S. C. H., Sijbrands, E. J. G., Ten Kate, G. L., Van Klaveren, D., Van Domburg, R. T., Van Der Steen, A. F. W., et al. (2013). Carotid intima-media thickness for cardiovascular risk assessment: systematic review and meta-analysis. Atherosclerosis 228, 1-11. doi:10.1016/j.atherosclerosis.2013.01.025
50. van Popele, N. M., Grobbee, D. E., Bots, M. L., Asman, R., Topouchian, J., Reneman, R. S., et al. (2001). Association between arterial stiffness and atherosclerosis - the Rotterdam study. Stroke 32, 454-460. doi:10.1161/01.STR.32.2.454
51. Welsh-Bohmer, K. A., and Mohs, R. C. (1997). Neuropsychological assess- ment of Alzheimer's disease. Neurology 49, S11-S13. doi:10.1212/WNL.49.3_Suppl_3.S11
52. Zlokovic, B. V. (2005). Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. 28, 202-208. doi:10.1016/j.tins.2005.02.001
53. Zureik, M., Temmar, M., Adamopoulos, C., Bureau, J. M., Courbon, D., Thomas, F., et al. (2002). Carotid plaques, but not common carotid intima-media thickness, are independently associated with aortic stiffness. J. Hypertens. 20, 85-93. doi:10.1097/00004872-200201000-00013