Monitoring Ara h 1, 2 and 3-sIgE and sIgG4 antibodies in peanut allergic children receiving oral rush immunotherapy

Pediatric Allergy and Immunology

Volumn 25, Issue 4, 2014, Pages 323-328

  Nozawa, Asako ^a   Okamoto, Yoshihisa ^a   Movérare, Robert ^b,c   Borres, Magnus P ^b,c   Kurihara, Kazuyunki ^a  

^a KANAGAWA CHILDREN'S MEDICAL CENTER   (Japan)

^b Thermo Fisher Scientific   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Children; Desensitization; IgE; IgG4; Oral immunotherapy; Peanut allergy

Indexed keywords

ARA H 1 ANTIGEN; ARA H 2 ANTIGEN; ARA H 3 ANTIGEN; ARA H 8 ANTIGEN; ARA H 9 ANTIGEN; FOOD ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4 ANTIBODY; PLACEBO; UNCLASSIFIED DRUG; ALLERGEN ARA H3; ARA H 1 PROTEIN, ARACHIS HYPOGAEA; ARA H 2 ALLERGEN, ARACHIS HYPOGAEA; GLYCOPROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; NAPIN; PLANT ANTIGEN; SEED STORAGE PROTEIN; VEGETABLE PROTEIN;

ADOLESCENT; ANAPHYLAXIS; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; JAPANESE (PEOPLE); MAINTENANCE THERAPY; MALE; MEDICAL HISTORY; ORAL IMMUNOTHERAPY; PATIENT MONITORING; PEANUT; PEANUT ALLERGY; PRIORITY JOURNAL; ADVERSE EFFECTS; BLOOD; CONTROLLED CLINICAL TRIAL; DESENSITIZATION; DRUG EFFECTS; FOLLOW UP; HUMORAL IMMUNITY; IMMUNOLOGY; JAPAN; ORAL DRUG ADMINISTRATION; PEANUT HYPERSENSITIVITY; PHYSIOLOGIC MONITORING; PRESCHOOL CHILD; PROCEDURES;

2S ALBUMINS, PLANT; ADMINISTRATION, ORAL; ADOLESCENT; ANTIGENS, PLANT; ARACHIS HYPOGAEA; CHILD; CHILD, PRESCHOOL; DESENSITIZATION, IMMUNOLOGIC; FEMALE; FOLLOW-UP STUDIES; GLYCOPROTEINS; HUMANS; IMMUNITY, HUMORAL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; JAPAN; MALE; MONITORING, PHYSIOLOGIC; PEANUT HYPERSENSITIVITY; PLANT PROTEINS; SEED STORAGE PROTEINS;

EID: 84904638882     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/pai.12243     Document Type: Article

References (16)

1. Santos AF, Lack G. Food allergy and anaphylaxis in pediatrics: update 2010-2012. Pediatr Allergy Immunol 2012: 23: 698-706.
2. Bock SA, Atkins FM. The natural history of peanut allergy. J Allergy Clin Immunol 1989: 83: 900-4.
3. Van der Leek TK, Liu AH, Stefanski K, Blacker B, Bock SA. The natural history of peanut allergy in young children and its association with serum peanut-specific IgE. J Pediatr 2000: 137: 749-55.
4. Imamura T, Kanagawa Y, Ebisawa M. A survey of patients with self-reported severe food allergies in Japan. Pediatr Allergy Immunol 2008: 19: 270-4.
5. Nowak-Wegrzyn A, Sampson HA. Future therapies for food allergies. J Allergy Clin Immunol 2011: 127: 558-73.
6. Beyer K. A European perspective on immunotherapy for food allergies. J Allergy Clin Immunol 2012: 129: 1179-84.
7. Itoh N, Itagaki Y, Kurihara K. Rush specific oral tolerance induction in school-age children with severe egg allergy: one year follow up. Allergol Int 2010: 59: 43-51.
8. Kurihara K. Immunotherapy for food allergy. Allergol Int 2010: 59: 9-14.
9. Fujino A, Kurihara K. [Two cases of rush specific oral tolerance induction for wheat allergy]. Arerugi 2010: 59: 1580-4. Japanese.
10. Ebisawa M, Moverare R, Sato S, Maruyama N, Borres MP, Komata T. Measurement of Ara h 1-, 2-, and 3-specific IgE antibodies is useful in diagnosis of peanut allergy in Japanese children. Pediatr Allergy Immunol 2012: 23: 573-81.
11. Anagnostou K, Clark A, King Y, Islam S, Deighton J, Ewan P. Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome. Clin Exp Allergy 2011: 41: 1273-81.
12. Garcia BE, Sanz ML, Gato JJ, Fernandez J, Oehling A. IgG4 blocking effect on the release of antigen-specific histamine. J Investig Allergol Clin Immunol 1993: 3: 26-33.
13. Ito K, Futamura M, Moverare R, et al. The usefulness of casein-specific IgE and IgG4 antibodies in cow's milk allergic children. Clin Mol Allergy 2012: 10: 1.
14. Vickery BP, Scurlock AM, Kulis M, et al. Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol 2014: 133: 468-75.
15. Jones SM, Pons L, Roberts JL, et al. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol 2009: 124: 292-300.
16. Varshney P, Jones SM, Scurlock AM, et al. A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response. J Allergy Clin Immunol 2011: 127: 654-60.