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Volumn 12, Issue 3, 2014, Pages 314-319

Achieving and maintaining an optimal trough level for prophylaxis in haemophilia: The past, the present and the future

Author keywords

Arthropathy; Haemophilia; Prophylaxis; Trough

Indexed keywords

BAY 79 4980; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR CONCENTRATE; HYBRID PROTEIN; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9; UNCLASSIFIED DRUG;

EID: 84904628977     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2014.0298-13     Document Type: Review
Times cited : (56)

References (31)
  • 1
    • 0002099315 scopus 로고
    • Haemophilia in Sweden. VII. Incidence, treatment and prophylaxis of arthropathy and other musculo-skeletal manifestations of haemophilia A and B
    • Ahlberg A. Haemophilia in Sweden. VII. Incidence, treatment and prophylaxis of arthropathy and other musculo-skeletal manifestations of haemophilia A and B. Acta Orthop Scand Suppl 1965; Suppl 77: 3-132.
    • (1965) Acta Orthop Scand Suppl , Issue.SUPPL. 77 , pp. 3-132
    • Ahlberg, A.1
  • 2
    • 0026635406 scopus 로고
    • Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B
    • Nilsson IM, Berntorp E, Lofqvist T, Pettersson H. Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B. J Intern Med 1992; 232: 25-32.
    • (1992) J Intern Med , vol.232 , pp. 25-32
    • Nilsson, I.M.1    Berntorp, E.2    Lofqvist, T.3    Pettersson, H.4
  • 3
    • 59849093369 scopus 로고    scopus 로고
    • Break-through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A
    • Collins PW, Blanchette VS, Fischer K, et al. Break-through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A. J Thromb Haemost 2009; 7: 413-20.
    • (2009) J Thromb Haemost , vol.7 , pp. 413-420
    • Collins, P.W.1    Blanchette, V.S.2    Fischer, K.3
  • 4
    • 79951923545 scopus 로고    scopus 로고
    • Analysis of low frequency bleeding data: The association of joint bleeds according to baseline FVIII activity levels
    • den Uijl IE, Fischer K, Van Der Bom JG, et al. Analysis of low frequency bleeding data: the association of joint bleeds according to baseline FVIII activity levels. Haemophilia 2011; 17: 41-4.
    • (2011) Haemophilia , vol.17 , pp. 41-44
    • Den Uijl, I.E.1    Fischer, K.2    Van Der Bom, J.G.3
  • 5
    • 84857951468 scopus 로고    scopus 로고
    • Clinical severity of haemophilia A: Does the classification of the 1950s still stand?
    • den Uijl IE, Mauser Bunschoten EP, Roosendaal G, et al. Clinical severity of haemophilia A: does the classification of the 1950s still stand? Haemophilia 2011; 17: 849-53.
    • (2011) Haemophilia , vol.17 , pp. 849-853
    • Den Uijl, I.E.1    Mauser Bunschoten, E.P.2    Roosendaal, G.3
  • 6
    • 84862867193 scopus 로고    scopus 로고
    • WFH: Closing the global gap-achieving optimal care
    • Skinner MW. WFH: closing the global gap-achieving optimal care. Haemophilia 2012; 18 (Suppl 4): 1-12.
    • (2012) Haemophilia , vol.18 , Issue.SUPPL. 4 , pp. 1-12
    • Skinner, M.W.1
  • 7
    • 84867166712 scopus 로고    scopus 로고
    • Association between physical activity and risk of bleeding in children with hemophilia
    • Broderick CR, Herbert RD, Latimer J, et al. Association between physical activity and risk of bleeding in children with hemophilia. JAMA 2012; 308: 1452-9.
    • (2012) JAMA , vol.308 , pp. 1452-1459
    • Broderick, C.R.1    Herbert, R.D.2    Latimer, J.3
  • 9
    • 84870255216 scopus 로고    scopus 로고
    • Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study
    • Dargaud Y, Wolberg AS, Luddington R, et al. Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: an international multicentre study. Thromb Res 2012; 130: 929-34.
    • (2012) Thromb Res , vol.130 , pp. 929-934
    • Dargaud, Y.1    Wolberg, A.S.2    Luddington, R.3
  • 10
    • 84859596442 scopus 로고    scopus 로고
    • Modern haemophilia care
    • Berntorp E, Shapiro AD. Modern haemophilia care. Lancet 2012; 379: 1447-56.
    • (2012) Lancet , vol.379 , pp. 1447-1456
    • Berntorp, E.1    Shapiro, A.D.2
  • 11
    • 84863192453 scopus 로고    scopus 로고
    • A comparison of traditional vs. Canadian tailored prophylaxis dosing of prophylactic factor infusions in children with haemophilia A and B in a single hemophilia treatment center
    • Dodd C, Watts RG. A comparison of traditional vs. Canadian tailored prophylaxis dosing of prophylactic factor infusions in children with haemophilia A and B in a single hemophilia treatment center. Haemophilia 2012; 18: 561-7.
    • (2012) Haemophilia , vol.18 , pp. 561-567
    • Dodd, C.1    Watts, R.G.2
  • 12
    • 84887192427 scopus 로고    scopus 로고
    • Intermediate-dose versus high-dose prophylaxis for severe hemophilia: Comparing outcome and costs since the 1970s
    • Fischer K, Steen CK, Petrini P, et al. Intermediate-dose versus high-dose prophylaxis for severe hemophilia: comparing outcome and costs since the 1970s. Blood 2013; 122: 1129-36.
    • (2013) Blood , vol.122 , pp. 1129-1136
    • Fischer, K.1    Steen, C.K.2    Petrini, P.3
  • 14
    • 84860320096 scopus 로고    scopus 로고
    • Identification and long-term observation of early joint damage by magnetic resonance imaging in clinically asymptomatic joints in patients with haemophilia A or B despite prophylaxis
    • Olivieri M, Kurnik K, Pfluger T, Bidlingmaier C. Identification and long-term observation of early joint damage by magnetic resonance imaging in clinically asymptomatic joints in patients with haemophilia A or B despite prophylaxis. Haemophilia 2012; 18: 369-74.
    • (2012) Haemophilia , vol.18 , pp. 369-374
    • Olivieri, M.1    Kurnik, K.2    Pfluger, T.3    Bidlingmaier, C.4
  • 15
    • 84868206189 scopus 로고    scopus 로고
    • Daily dosing prophylaxis for haemophilia: A randomized crossover pilot study evaluating feasibility and efficacy
    • Lindvall K, Astermark J, Bjorkman S, et al. Daily dosing prophylaxis for haemophilia: a randomized crossover pilot study evaluating feasibility and efficacy. Haemophilia 2012; 18: 855-9.
    • (2012) Haemophilia , vol.18 , pp. 855-859
    • Lindvall, K.1    Astermark, J.2    Bjorkman, S.3
  • 17
    • 84857572936 scopus 로고    scopus 로고
    • A randomized comparison of two prophylaxis regimens and a paired comparison of on-demand and prophylaxis treatments in hemophilia A management
    • Valentino LA, Mamonov V, Hellmann A, et al. A randomized comparison of two prophylaxis regimens and a paired comparison of on-demand and prophylaxis treatments in hemophilia A management. J Thromb Haemost 2012; 10: 359-67.
    • (2012) J Thromb Haemost , vol.10 , pp. 359-367
    • Valentino, L.A.1    Mamonov, V.2    Hellmann, A.3
  • 18
    • 77956489886 scopus 로고    scopus 로고
    • Blood-induced joint disease: The pathophysiology of hemophilic arthropathy
    • Valentino LA. Blood-induced joint disease: the pathophysiology of hemophilic arthropathy. J Thromb Haemost 2010; 8: 1895-902.
    • (2010) J Thromb Haemost , vol.8 , pp. 1895-1902
    • Valentino, L.A.1
  • 19
    • 84859197329 scopus 로고    scopus 로고
    • Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients
    • Powell JS, Josephson NC, Quon D, et al. Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients. Blood 2012; 119: 3031-7.
    • (2012) Blood , vol.119 , pp. 3031-3037
    • Powell, J.S.1    Josephson, N.C.2    Quon, D.3
  • 20
    • 84870336472 scopus 로고    scopus 로고
    • Efficacy and safety of prophylaxis with once-weekly BAY 79-4980 compared with thrice-weekly rFVIII-FS in haemophilia A patients. A randomised, active-controlled, double-blind study
    • Powell J, Martinowitz U, Windyga J, et al. Efficacy and safety of prophylaxis with once-weekly BAY 79-4980 compared with thrice-weekly rFVIII-FS in haemophilia A patients. A randomised, active-controlled, double-blind study. Thromb Haemost 2012; 108: 913-22.
    • (2012) Thromb Haemost , vol.108 , pp. 913-922
    • Powell, J.1    Martinowitz, U.2    Windyga, J.3
  • 21
    • 84880605895 scopus 로고    scopus 로고
    • Future of coagulation factor replacement therapy
    • Peyvandi F, Garagiola I, Seregni S. Future of coagulation factor replacement therapy. J Thromb Haemost 2013; 11 (Suppl 1): 84-98.
    • (2013) J Thromb Haemost , vol.11 , Issue.SUPPL. 1 , pp. 84-98
    • Peyvandi, F.1    Garagiola, I.2    Seregni, S.3
  • 22
    • 84868152441 scopus 로고    scopus 로고
    • Population pharmacokinetic modeling for dose setting of nonacog beta pegol (N9-GP), a glycoPEGylated recombinant factor IX
    • Collins PW, Moss J, Knobe K, et al. Population pharmacokinetic modeling for dose setting of nonacog beta pegol (N9-GP), a glycoPEGylated recombinant factor IX. J Thromb Haemost 2012; 10: 2305-12.
    • (2012) J Thromb Haemost , vol.10 , pp. 2305-2312
    • Collins, P.W.1    Moss, J.2    Knobe, K.3
  • 23
    • 84879462669 scopus 로고    scopus 로고
    • Novel coagulation factor concentrates: Issues relating to their clinical implementation and pharmacokinetic assessment for optimal prophylaxis in haemophilia patients
    • Ljung R, Auerswald G, Benson G, et al. Novel coagulation factor concentrates: issues relating to their clinical implementation and pharmacokinetic assessment for optimal prophylaxis in haemophilia patients. Haemophilia 2013; 19: 481-6.
    • (2013) Haemophilia , vol.19 , pp. 481-486
    • Ljung, R.1    Auerswald, G.2    Benson, G.3
  • 24
    • 84876182114 scopus 로고    scopus 로고
    • Enhancing the pharmacokinetic properties of recombinant factor VIII: First-in-human trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A
    • Tiede A, Brand B, Fischer R, et al. Enhancing the pharmacokinetic properties of recombinant factor VIII: first-in-human trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A. J Thromb Haemost 2013; 11: 670-8.
    • (2013) J Thromb Haemost , vol.11 , pp. 670-678
    • Tiede, A.1    Brand, B.2    Fischer, R.3
  • 25
    • 38349083504 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A
    • Powell JS, Nugent DJ, Harrison JA, et al. Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost 2008; 6: 277-83.
    • (2008) J Thromb Haemost , vol.6 , pp. 277-283
    • Powell, J.S.1    Nugent, D.J.2    Harrison, J.A.3
  • 26
    • 80052669248 scopus 로고    scopus 로고
    • Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: A first human dose trial in patients with hemophilia B
    • Negrier C, Knobe K, Tiede A, et al. Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B. Blood 2011; 118: 2695-701.
    • (2011) Blood , vol.118 , pp. 2695-2701
    • Negrier, C.1    Knobe, K.2    Tiede, A.3
  • 27
    • 84862908041 scopus 로고    scopus 로고
    • Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients
    • Shapiro AD, Ragni MV, Valentino LA, et al. Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients. Blood 2012; 119: 666-72.
    • (2012) Blood , vol.119 , pp. 666-672
    • Shapiro, A.D.1    Ragni, M.V.2    Valentino, L.A.3
  • 28
    • 84889769562 scopus 로고    scopus 로고
    • Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B
    • Powell JS, Pasi KJ, Ragni MV, et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med 2013; 369: 2313-23.
    • (2013) N Engl J Med , vol.369 , pp. 2313-2323
    • Powell, J.S.1    Pasi, K.J.2    Ragni, M.V.3
  • 29
    • 84875522099 scopus 로고    scopus 로고
    • PROLONG-9FP clinical development program - Phase I results of recombinant fusion protein linking coagulation factor IX with recombinant albumin (rIX-FP)
    • Santagostino E. PROLONG-9FP clinical development program - phase I results of recombinant fusion protein linking coagulation factor IX with recombinant albumin (rIX-FP). Thromb Res 2013; 131 (Suppl 2): S7-10.
    • (2013) Thromb Res , vol.131 , Issue.SUPPL. 2
    • Santagostino, E.1
  • 30
    • 84866594053 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients
    • Santagostino E, Negrier C, Klamroth R, et al. Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients. Blood 2012; 120: 2405-11.
    • (2012) Blood , vol.120 , pp. 2405-2411
    • Santagostino, E.1    Negrier, C.2    Klamroth, R.3
  • 31
    • 84875539641 scopus 로고    scopus 로고
    • Phase I/II, open-label, multicenter, safety, efficacy and PK study of a recombinant coagulation factor IX albumin fusion protein (rIX-FP) in subjects with hemophilia B
    • Martinowitz U, Lubetsky A. Phase I/II, open-label, multicenter, safety, efficacy and PK study of a recombinant coagulation factor IX albumin fusion protein (rIX-FP) in subjects with hemophilia B. Thromb Res 2013; 131 (Suppl 2): S11-14.
    • (2013) Thromb Res , vol.131 , Issue.SUPPL. 2
    • Martinowitz, U.1    Lubetsky, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.