Effect of the endothelin type A-selective endothelin receptor antagonist ambrisentan on digital ulcers in patients with systemic sclerosis: Results of a prospective pilot study

Journal of the American Academy of Dermatology

Volumn 71, Issue 2, 2014, Pages 400-401

  Chung, Lorinda ^a,b   Ball, Katharine ^a   Yaqub, Aaliya ^a   Lingala, Bharathi ^a   Fiorentino, David ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBRISENTAN; BOSENTAN;

CLINICAL ARTICLE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FINGER ULCER; HUMAN; LETTER; MALE; OPEN STUDY; PERIPHERAL EDEMA; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SYSTEMIC SCLEROSIS; ULCER HEALING;

ADULT; FEMALE; FINGERS; HUMANS; MALE; MIDDLE AGED; PHENYLPROPIONATES; PILOT PROJECTS; PROSPECTIVE STUDIES; PYRIDAZINES; RECEPTOR, ENDOTHELIN A; SCLERODERMA, SYSTEMIC; SKIN ULCER;

EID: 84904612564     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2014.04.028     Document Type: Article

References (4)

1. J.H. Korn, M. Mayes, M. Matucci Cerinic, M. Rainisio, J. Pope, and E. Hachulla et al. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist Arthritis Rheum 50 2004 3985 3993
2. M. Matucci-Cerinic, C.P. Denton, D.E. Furst, M.D. Mayes, V.M. Hsu, and P. Carpentier et al. Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial Ann Rheum Dis 70 2011 32 38
3. J.J. Maguire, R.E. Kuc, and A.P. Davenport Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues Life Sci 91 2012 681 686
4. S. Parisi, C.L. Peroni, A. Lagana, M. Scarati, F. Ambrogio, and M. Bruzzone et al. Efficacy of ambrisentan in the treatment of digital ulcers in patients with systemic sclerosis: a preliminary study Rheumatology 52 2013 1142 1144