Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: Risk factors for paediatric intensive-care-unit admission

Epidemiology and Infection

Volumn 142, Issue 9, 2014, Pages 1826-1835

  Rebolledo, J ^a,b   Igoe, D ^a   O'Donnell, J ^a   Domegan, L ^a   Boland, M ^c   Freyne, B ^d   McNamara, A ^c   Molloy, E ^d,e   Callaghan, M ^e   Ryan, A ^c   O'Flanagan, D ^a  

^a HEALTH PROTECTION SURVEILLANCE CENTRE   (Ireland)

^b EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL ECDC   (Sweden)

^c HEALTH SERVICE EXECUTIVE   (Ireland)

^d NATIONAL MATERNITY HOSPITAL   (Ireland)

^e OUR LADY S CHILDREN S HOSPITAL   (Ireland)

Author keywords

immunization (vaccination); Infectious disease epidemiology; influenza; paediatrics; pandemic

Indexed keywords

ANTIVIRUS AGENT;

ADOLESCENT; ANTIVIRAL THERAPY; ARTICLE; CHILD; COHORT ANALYSIS; COMPARATIVE STUDY; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HOSPITALIZED CHILD; HUMAN; INFLUENZA A (H1N1)PDM09; INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; INTENSIVE CARE UNIT; IRELAND; MALE; PANDEMIC; PANDEMIC INFLUENZA; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; CONTROLLED STUDY; HOSPITALIZATION; INFECTION RISK; INFLUENZA A (H1N1); INFLUENZA VIRUS; MAJOR CLINICAL STUDY; NONHUMAN; PRESCHOOL CHILD; SCHOOL CHILD; SEASON; SPECIES COMPARISON;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HOSPITALIZATION; HUMANS; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTENSIVE CARE UNITS, PEDIATRIC; IRELAND; MALE; RISK FACTORS;

EID: 84904602759     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268813002732     Document Type: Article

References (37)

1. Dawood FS, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. New England Journal of Medicine 2009; 360: 2605-2615.
2. Dawood FS, et al. Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study. Lancet Infectious Diseases 2012; 12: 687-695.
3. Cox CM, et al. 2009 pandemic influenza A (H1N1) deaths among children - United States, 2009-2010. Clinical Infectious Diseases 2011; 52 (Suppl. 1): S69-S74.
4. Stein M, et al. Hospitalization of children with influenza A(H1N1) virus in Israel during the 2009 outbreak in Israel: a multicenter survey. Archives of Pediatrics and Adolescent Medicine 2010; 164: 1015-1022.
5. Health Service Executive Immunisation Website. Pandemic (H1N1) 2009 influenza. It stops with you. Frequently asked questions for health professionals, January 2010 (http://www.immunisation.ie/en/Healthcare Professionals/PandemicCampaign2009/). Accessed 13 November 2012.
6. Libster R, et al. Pediatric hospitalisations associated with 2009 pandemic influenza (H1N1) in Argentina. New England Journal of Medicine 2010; 362: 45-55.
7. Morris SK, et al. A retrospective cross-sectional study of risk factors and clinical spectrum of children admitted to hospital with pandemic H1N1 influenza as compared to influenza A. British Medical Journal Open. Published online: 11 March 2012. doi: 10.1136/bmjopen-2011-000310.
8. Engelhard D, et al. Increased extent of and risk factors for pandemic (H1N1) 2009 and seasonal influenza among children, Israel. Emerging Infectious Diseases 2011; 17: 1740-1743.
9. Bolotin S, et al. A new sentinel surveillance system for severe influenza in England shows a shift in age distribution of hospitalised cases in the post-pandemic period. PLoS One. Published online: 23 January 2012. doi: 10.1371/journal.pone.0030279.
10. Mytton OT, Rutter PD, Donaldson LJ. Influenza A(H1N1)pdm09 in England, 2009 to 2011: a greater burden of severe illness in the year after the pandemic than in the pandemic year. Eurosurveillance 2012; 17 (14): pii=20139.
11. Altmann M, et al. Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season. Emerging Infectious Diseases. Published online: 9 November 2012. doi: 10.3201/eid1811. 120719.
12. Cullen G, et al. Surveillance of the first 205 confirmed hospitalised cases of pandemic H1N1 influenza in Ireland, 28 April-3 October 2009. Eurosurveillance 2009; 14(44): pii=19389.
13. Carr M, et al. Development of a real-time RT-PCR for the detection of swine-lineage influenza A (H1N1) virus infections. Journal of Clinical Virology 2009; 45: 196-199.
14. Hosmer DW, Lemeshow S. Applied Logistic Regression. New York: Wiley, 2000.
15. The Irish Statute Book (Government of Ireland). Infectious Diseases Regulations 1981. S.I. No. 390 of 1981 (http://www.irishstatutebook.ie/1981/en/ si/0390.html).
16. Domegan L et al. Epidemiology of influenza in Ireland for the 2010/2011 influenza season. Epi-Insight, 2011, volume 12, issue 11 (http://ndsc. newsweaver.ie/epiinsight/dobfuin7on4?a=1&p=18519315&t=17517774). Accessed 10 July 2013.
17. Cotter S, et al. National Summary of Influenza pandemic (H1N1) 2009 vaccination in Ireland - provisional data. Epi-Insight, 2010, volume 11, issue 9 (http://ndsc.newsweaver.ie/epiinsight/viz7qx9a6lrqkeph6tk9uv). Accessed 13 November 2012.
18. Bettinger JA, et al. Pandemic influenza in Canadian children: a summary of hospitalized pediatric cases. Vaccine 2010; 28: 3180-3184.
19. Costello BE, et al. Pandemic H1N1 influenza in the pediatric emergency department: a comparison with previous seasonal influenza outbreaks. Annals of Emergency Medicine 2010; 56: 643-648.
20. Kobayashi M, et al. Pediatric hospitalizations with influenza A infection during the 2009-2010 pandemic in five hospitals in Japan. Pediatrics International 2012; 54: 613-618.
21. Larcombe P, et al. Pandemic (H1N1) 2009: a clinical spectrum in the general paediatric population. Archives of Disease in Childhood 2011; 96: 96-98.
22. Ko JH, et al. Characteristics of hospitalized children with 2009 pandemic influenza A (H1N1): a multicenter study in Korea. Journal of Korean Medical Science 2012; 27: 408-415.
23. Del Rosal T, et al. Pandemic H1N1 influenza-associated hospitalizations in children in Madrid, Spain. Influenza and other Respiratory Viruses 2011; 5: e544-51.
24. O'Riordan S, et al. Risk factors and outcomes among children admitted to hospital with pandemic H1N1 influenza. Canadian Medical Association Journal 2010; 182: 39-44.
25. Tran D, et al. Comparison of children hospitalised with seasonal versus pandemic influenza A, 2004-2009. Pediatrics 2012; 130: 397-406.
26. Nicolay N, et al. Epidemiology, clinical characteristics and resource implications of pandemic (H1N1) 2009 in intensive care units in Ireland. Critical Care and Resuscitation 2010; 12: 255-261.
27. Wieching A, et al. Clinical characteristics of pediatric hospitalizations associated with 2009 pandemic influenza a(H1N1) in Bavaria, Germany. BMC Research Notes 2012; 5: 304.
28. Çiftçi E, et al. Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: experience from multiple tertiary paediatric centres in Turkey. Scandinavian Journal of Infectious Diseases 2011; 43: 923-929.
29. Altmann M, et al. Severe cases of pandemic (H1N1) 2009 in children, Germany. Emerging Infectious Diseases 2011; 17: 186-192.
30. Blumental S, et al. Pandemic A/H1N1v influenza 2009 in hospitalized children: a multicenter Belgian survey. BMC Infectious Diseases 2011; 11: 313.
31. Van Zwol A, et al. Clinical features of a Dutch cohort of critically ill children due to the 2009 new influenza A H1N1 pandemic. Clinical Pediatrics 2011; 50: 69-72.
32. Bagdure D, et al. Hospitalized children with 2009 pandemic influenza A (H1N1): comparison to seasonal influenza and risk factors for admission to the ICU. PLoS One. Published online: 15 December 2010. doi: 10.1371/journal.pone. 0015173.
33. Centers for Disease Control and Prevention (CDC). Influenza-associated pediatric deaths - United States, September 2010-August 2011. Morbidity and Mortality Weekly Report 2011; 60: 1233-1238.
34. Garg S, et al. Reduced influenza antiviral treatment among children and adults hospitalised with laboratory confirmed influenza infection in the year after the 2009 pandemic. Clinical Infectious Diseases. Published online: 27 April 2012. doi: 10.1093/cid/cis442.
35. Xu C, et al. Characteristics of hospitalized cases with influenza A (H1N1)pdm09 infection during first winter season of post-pandemic in China. PLoS One 2013; 8: e55016.
36. Choi WI, et al. Male predominance of pneumonia and hospitalization in pandemic influenza A (H1N1) 2009 infection. Indian Journal of Medical Research 2012; 135: 534-537.
37. Esposito S, et al. Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009. BMC Infectious Diseases. Published online: 12 October 2011. doi: 10.1186/1471-2334-11-271.