-
3
-
-
4644242707
-
The natural history of epilepsy: An epidemiological view
-
Kwan P, Sander JW. The natural history of epilepsy: an epidemiological view. J Neurol Neurosurg Psychiatry. 2004; 75:1376-81.
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 1376-1381
-
-
Kwan, P.1
Sander, J.W.2
-
4
-
-
84878369311
-
Pharmacological treatment strategies: Mechanisms of antiepileptic drugs
-
Potschka H. Pharmacological treatment strategies: mechanisms of antiepileptic drugs. Epileptology. 2013; 1:31-7.
-
(2013)
Epileptology
, vol.1
, pp. 31-37
-
-
Potschka, H.1
-
5
-
-
84908301329
-
Glutamate receptors
-
White HS, Rho JM, eds. New York: Professional Communications
-
Glutamate receptors. In: White HS, Rho JM, eds. Mechanisms of action of antiepileptic drugs. 1st ed. New York: Professional Communications; 2010:71-84.
-
(2010)
Mechanisms of Action of Antiepileptic Drugs. 1st Ed.
, pp. 71-84
-
-
-
6
-
-
84865750536
-
Perampanel study 207: Long-term open-label evaluation in patients with epilepsy
-
Rektor I, Krauss GL, Bar M et al. Perampanel study 207: long-term open-label evaluation in patients with epilepsy. Acta Neurol Scand. 2012; 126:263-9.
-
(2012)
Acta Neurol Scand
, vol.126
, pp. 263-269
-
-
Rektor, I.1
Krauss, G.L.2
Bar, M.3
-
7
-
-
0029777313
-
The dawn of excitatory amino acid research in Japan. The pioneering work by Professor Takashi Hayashi
-
Takagaki G. The dawn of excitatory amino acid research in Japan. The pioneering work by Professor Takashi Hayashi. Neurochem Int. 1996; 29:225-9.
-
(1996)
Neurochem Int
, vol.29
, pp. 225-229
-
-
Takagaki, G.1
-
8
-
-
0027262604
-
Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
-
During MJ, Spencer DD. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet. 1993; 341:1607-10.
-
(1993)
Lancet
, vol.341
, pp. 1607-1610
-
-
During, M.J.1
Spencer, D.D.2
-
9
-
-
0035214976
-
Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging
-
Le DA, Lipton SA. Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging. Drugs Aging. 2001; 18:717-24.
-
(2001)
Drugs Aging
, vol.18
, pp. 717-724
-
-
Le, D.A.1
Lipton, S.A.2
-
10
-
-
84856685605
-
Revisiting AMPA receptors as an antiepileptic drug target
-
Rogawski MA. Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Curr. 2011; 11:56-63.
-
(2011)
Epilepsy Curr
, vol.11
, pp. 56-63
-
-
Rogawski, M.A.1
-
11
-
-
84873482399
-
Perampanel as adjunctive therapy in patients with partial onset seizures
-
Plosker GL. Perampanel as adjunctive therapy in patients with partial onset seizures. CNS Drugs. 2012; 26:1085-96.
-
(2012)
CNS Drugs
, vol.26
, pp. 1085-1096
-
-
Plosker, G.L.1
-
12
-
-
33846188141
-
Molecular targets for antiepileptic drug development
-
Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics. 2007; 4:18-61.
-
(2007)
Neurotherapeutics
, vol.4
, pp. 18-61
-
-
Meldrum, B.S.1
Rogawski, M.A.2
-
13
-
-
20444429431
-
Glutamate receptor ion channels
-
Mayer ML. Glutamate receptor ion channels. Curr Opin Neurobiol. 2005; 15: 282-8.
-
(2005)
Curr Opin Neurobiol
, vol.15
, pp. 282-288
-
-
Mayer, M.L.1
-
14
-
-
0032486422
-
The tetrameric structure of a glutamate receptor channel
-
Rosenmund C, Stern-Bach Y, Stevens CF. The tetrameric structure of a glutamate receptor channel. Science. 1998; 280:1596-9.
-
(1998)
Science
, vol.280
, pp. 1596-1599
-
-
Rosenmund, C.1
Stern-Bach, Y.2
Stevens, C.F.3
-
15
-
-
0036459021
-
Implications for neuroprotective treatments
-
Meldrum BS. Implications for neuroprotective treatments. Prog Brain Res. 2002; 135:487-95.
-
(2002)
Prog Brain Res
, vol.135
, pp. 487-495
-
-
Meldrum, B.S.1
-
17
-
-
84870775724
-
Perampanel - New promise for refractory epilepsy?
-
News
-
Löscher W, Schmidt D. Perampanel - new promise for refractory epilepsy? Nat Rev Neurol. 2012; 8:661-2. News.
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 661-662
-
-
Löscher, W.1
Schmidt, D.2
-
18
-
-
84875201902
-
Novel treatment options for epilepsy: Focus on perampanel
-
Franco V, Crema F, Iudice A et al. Novel treatment options for epilepsy: focus on perampanel. Pharmacol Res. 2013; 70:35-40.
-
(2013)
Pharmacol Res
, vol.70
, pp. 35-40
-
-
Franco, V.1
Crema, F.2
Iudice, A.3
-
20
-
-
84873461794
-
Population pharmacokinetics of perampanel, a selective, noncompetitive AMPA receptor antagonist, in patients with refractory partial-onset seizures participating in a randomized, double-blind, placebo-controlled phase III study
-
Abstract
-
Hussein Z, Critchley D, Ferry J et al. Population pharmacokinetics of perampanel, a selective, noncompetitive AMPA receptor antagonist, in patients with refractory partial-onset seizures participating in a randomized, double-blind, placebo-controlled phase III study. Epilepsia. 2011; 52(suppl 6):248-9. Abstract.
-
(2011)
Epilepsia
, vol.52
, pp. 248-249
-
-
Hussein, Z.1
Critchley, D.2
Ferry, J.3
-
21
-
-
84872729246
-
Population pharmacokinetics and pharmacodynamics of perampanel in patients with refractory partial seizures
-
Abstract
-
Fuseau E, Templeton D, Hussein Z. Population pharmacokinetics and pharmacodynamics of perampanel in patients with refractory partial seizures. Epilepsy Curr. 2011; 11(suppl 1):1.254. Abstract.
-
(2011)
Epilepsy Curr
, vol.11
, pp. 1.254
-
-
Fuseau, E.1
Templeton, D.2
Hussein, Z.3
-
22
-
-
84857286001
-
Pharmacokinetics of perampanel, a highly selective AMPA-type glutamate receptor antagonist
-
Abstract
-
Templeton D. Pharmacokinetics of perampanel, a highly selective AMPA-type glutamate receptor antagonist. Epilepsia. 2009; 50(suppl 11):98. Abstract.
-
(2009)
Epilepsia
, vol.50
, pp. 98
-
-
Templeton, D.1
-
23
-
-
84872054640
-
Population pharmacokinetics and pharmacodynamics of perampanel: A pooled analysis from three phase III trials
-
Abstract
-
Laurenza A, Ferry J, Hussein Z. Population pharmacokinetics and pharmacodynamics of perampanel: a pooled analysis from three phase III trials. Epilepsy Curr. 2012; 12(suppl 1):2.231. Abstract.
-
(2012)
Epilepsy Curr
, vol.12
, pp. 2.231
-
-
Laurenza, A.1
Ferry, J.2
Hussein, Z.3
-
25
-
-
84865719107
-
Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 304
-
French JA, Krauss GL, Biton V et al. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology. 2012; 79: 589-96.
-
(2012)
Neurology
, vol.79
, pp. 589-596
-
-
French, J.A.1
Krauss, G.L.2
Biton, V.3
-
26
-
-
84872090913
-
Evaluation of adjunctive perampanel in patients with refractory partial-onset seizures: Results of randomized global phase III study 305
-
French JA, Krauss GL, Steinhoff BJ et al. Evaluation of adjunctive perampanel in patients with refractory partial-onset seizures: results of randomized global phase III study 305. Epilepsia. 2013; 54:117-25.
-
(2013)
Epilepsia
, vol.54
, pp. 117-125
-
-
French, J.A.1
Krauss, G.L.2
Steinhoff, B.J.3
-
27
-
-
84860755687
-
Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 306
-
Krauss GL, Serratosa JM, Villanueva V. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 306. Neurology. 2012; 78:1408-15.
-
(2012)
Neurology
, vol.78
, pp. 1408-1415
-
-
Krauss, G.L.1
Serratosa, J.M.2
Villanueva, V.3
-
28
-
-
84872078864
-
Perampanel, a selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: Interim results from phase III, extension study 307
-
Krauss GL, Perucca E, Ben-Menachem E et al. Perampanel, a selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: interim results from phase III, extension study 307. Epilepsia. 2013; 54:126-34.
-
(2013)
Epilepsia
, vol.54
, pp. 126-134
-
-
Krauss, G.L.1
Perucca, E.2
Ben-Menachem, E.3
-
29
-
-
84873428999
-
Analysis of seizure frequency reduction by concomitant antiepileptic drug (AED) use with adjunctive perampanel: Pooled phase III results
-
Abstract
-
Trinka E, Straub H, Squillacote D et al. Analysis of seizure frequency reduction by concomitant antiepileptic drug (AED) use with adjunctive perampanel: pooled phase III results. Epilepsia. 2012; 53(suppl 5):194-5. Abstract.
-
(2012)
Epilepsia
, vol.53
, pp. 194-195
-
-
Trinka, E.1
Straub, H.2
Squillacote, D.3
-
30
-
-
84155186559
-
Tolerability and safety of perampanel: Two randomized dose-escalation studies
-
Krauss GL, Bar M, Biton V et al. Tolerability and safety of perampanel: two randomized dose-escalation studies. Acta Neurol Scand. 2012; 125:8-15.
-
(2012)
Acta Neurol Scand
, vol.125
, pp. 8-15
-
-
Krauss, G.L.1
Bar, M.2
Biton, V.3
|