Body positioning and medical therapy for infantile gastroesophageal reflux symptoms

Journal of Pediatric Gastroenterology and Nutrition

Volumn 59, Issue 2, 2014, Pages 237-243

  Loots, Clara ^a   Kritas, Stamatiki ^b   Van Wijk, Michiel ^a   McCall, Lisa ^b   Peeters, Laura ^a   Lewindon, Peter ^c   Bijlmer, Rob ^d   Haslam, Ross ^d   Tobin, Jacinta ^e   Benninga, Marc ^a   Davidson, Geoffrey ^b   Omari, Taher ^b  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

^b FLINDERS UNIVERSITY   (Australia)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

^d Intensive Care Unit   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

diagnosis; gastroesophageal reflux; treatment

Indexed keywords

ESOMEPRAZOLE; GAVISCON; MYLANTA; PARACETAMOL; PLACEBO; SIMETHICONE; PROTON PUMP INHIBITOR;

ARTICLE; BODY POSITION; BREATH ANALYSIS; CONSTIPATION; CONTROLLED STUDY; CRYING; DIARRHEA; DOUBLE BLIND PROCEDURE; FAILURE TO THRIVE; FEEDING DIFFICULTY; FEMALE; GASTROESOPHAGEAL REFLUX; HEAD OF COT ELEVATION; HUMAN; INFANT; INFANT DISEASE; IRRITABILITY; LEFT LATERAL POSITION; MAJOR CLINICAL STUDY; MALE; NEWBORN; PALLIATIVE THERAPY; PATIENT MONITORING; PHARMACEUTICAL CARE; POSTPRANDIAL STATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RETREATMENT; ROTAVIRUS INFECTION; SLEEP DISORDER; STOMACH EMPTYING; STOMACH MOTILITY; STOMACH PH; SUDDEN INFANT DEATH SYNDROME; SYMPTOM ASSESSMENT; TREATMENT OUTCOME; TREATMENT RESPONSE; URINARY TRACT INFECTION; VOMITING; WEIGHT REDUCTION; COMPLICATION; MENTAL STRESS; MULTIMODALITY CANCER THERAPY; PATIENT POSITIONING;

COMBINED MODALITY THERAPY; CRYING; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; INFANT; INFANT, NEWBORN; MALE; PATIENT POSITIONING; PROSPECTIVE STUDIES; PROTON PUMP INHIBITORS; STRESS, PSYCHOLOGICAL; VOMITING;

EID: 84904594939     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0000000000000395     Document Type: Article

References (32)

1. Van Howe RS, Storms MR. Gastroesophageal reflux symptoms in infants in a rural population: longitudinal data over the first six months. BMC Pediatr 2010;10:7.
2. Omari TI, Barnett C, Snel A, et al. Mechanisms of gastroesophageal reflux in healthy premature infants. J Pediatr 1998;133:650-4.
3. Omari TI, Barnett CP, Benninga MA, et al. Mechanisms of gastrooesophageal reflux in preterm and term infants with reflux disease. Gut 2002;51:475-9.
4. Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995;268 (1 pt 1):G128-33.
5. Boeckxstaens GE, Hirsch DP, Fakhry N, et al. Involvement of cholecystokinin A receptors in transient lower esophageal sphincter relaxations triggered by gastric distension. Am J Gastroenterol 1998;93: 1823-8.
6. Mittal RK, Holloway RH, Penagini R, et al. Transient lower esophageal sphincter relaxation. Gastroenterology 1995;109:601-10.
7. Zerbib F, Bruley D, Scarpignato V, et al. Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans. Am J Physiol 1998;275 (6 pt 1):G1266-73.
8. Loots CM, Benninga MA, Davidson GP, et al. Addition of pHimpedance monitoring to standard pH monitoring increases the yield of symptom association analysis in infants and children with gastroesophageal reflux. J Pediatr 2009;154:248-52.
9. Rosen R, Lord C, Nurko S. The sensitivity of multichannel intraluminal impedance and the pH probe in the evaluation of gastroesophageal reflux in children. Clin Gastroenterol Hepatol 2006;4:167-72.
10. Salvatore S, Arrigo S, Luini C, et al. Esophageal impedance in children: symptom-based results. J Pediatr 2010;157:949-54.
11. Barron JJ, Tan H, Spalding J, et al. Proton pump inhibitor utilization patterns in infants. J Pediatr Gastroenterol Nutr 2007;45:421-7.
12. Higginbotham TW. Effectiveness and safety of proton pump inhibitors in infantile gastroesophageal reflux disease. Ann Pharmacother 2010; 44:572-6.
13. Orenstein SR, Hassall E, Furmaga-Jablonska W, et al. Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease. J Pediatr 2009;154:514-20.
14. van der Pol RJ, Smits MJ, van Wijk MP, et al. Efficacy of proton-pump inhibitors in children with gastroesophageal reflux disease: a systematic review. Pediatrics 2011;127:925-35.
15. Omari TI, Haslam RR, Lundborg P, et al. Effect of omeprazole on acid gastroesophageal reflux and gastric acidity in preterm infants with pathological acid reflux. J Pediatr Gastroenterol Nutr 2007;44:41-4.
16. Moore DJ, Tao BS, Lines DR, et al. Double-blind placebo-controlled trial of omeprazole in irritable infants with gastroesophageal reflux. J Pediatr 2003;143:219-23.
17. Omari TI, Lundborg P, Sandstrom M, et al. Pharmacodynamics and systemic exposure of esomeprazole in preterm infants and term neonates with gastroesophageal reflux disease. J Pediatr 2009;155:222-8.
18. Omari TI, Rommel N, Staunton E, et al. Paradoxical impact of body positioning on gastroesophageal reflux and gastric emptying in the premature neonate. J Pediatr 2004;145:194-200.
19. van Wijk MP, Benninga MA, Dent J, et al. Effect of body position changes on postprandial gastroesophageal reflux and gastric emptying in the healthy premature neonate. J Pediatr 2007;151:585-90.
20. vanWijk MP, Benninga MA, Davidson GP, et al. Small volumes of feed can trigger transient lower esophageal sphincter relaxation and gastroesophageal reflux in the right lateral position in infants. J Pediatr 2010; 156:744-8.
21. Omari T. Gastroesophageal reflux in infants: can a simple left side positioning strategy help this diagnostic and therapeutic conundrum? Minerva Pediatr 2008;60:193-200.
22. McClure RJ, Kristensen JH, Grauaug A. Randomised controlled trial of cisapride in preterm infants. Arch Dis Child Fetal Neonatal Ed 1999;80:F174-7.
23. Blair PS, Platt MW, Smith IJ, et al. Sudden infant death syndrome and sleeping position in pre-term and low birth weight infants: an opportunity for targeted intervention. Arch Dis Child 2006;91:101-6.
24. Mitchell EA. Recommendations for sudden infant death syndrome prevention: a discussion document. Arch Dis Child 2007;92:155-9.
25. Sifrim D, Holloway R, Silny J, et al. Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001;120:1588-98.
26. Weusten BL, Roelofs JM, Akkermans LM, et al. The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data. Gastroenterology 1994;107:1741-5.
27. Omari TI, Symonds E, Davidson GP, et al. Is the correction factor used in the breath test assessment of gastric emptying appropriate for use in infants? J Pediatr Gastroenterol Nutr 2005;41:332-4.
28. Winter H, Kum-Nji P, Mahomedy SH, et al. Efficacy and safety of pantoprazole delayed-release granules for oral suspension in a placebocontrolled treatment-withdrawal study in infants 1-11 months old with symptomatic GERD. J Pediatr Gastroenterol Nutr 2010;50:609-18.
29. Omari TI, Schwarzer A, vanWijk MP, et al. Optimisation of the refluxsymptom association statistics for use in infants being investigated by 24-hour pH impedance. J Pediatr Gastroenterol Nutr 2011;52:408-13.
30. Lopez-Alonso M, Moya MJ, Cabo JA, et al. Twenty-four-hour esophageal impedance-ph monitoring in healthy preterm neonates: rate and characteristics of acid, weakly acidic, and weakly alkaline gastroesophageal reflux. Pediatrics 2006;118:e299-308.
31. Loots CM, van Wijk MP, Blondeau K, et al. Interobserver and intraobserver variability in pH-impedance analysis between 10 experts and automated analysis. J Pediatr 2012;160:441.
32. Barnett CP, Omari T, Davidson GP, et al. Effect of cisapride on gastric emptying in premature infants with feed intolerance. J Paediatr Child Health 2001;37:559-63.