NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol

Journal of Biological Chemistry

Volumn 289, Issue 29, 2014, Pages 20039-20053

  Yang, Jianbo ^a   Singh, Varsha ^a   Chen, Tian E ^a   Sarker, Rafiquel ^a   Xiong, Lishou ^a,b   Cha, Boyoung ^a   Jin, Shi ^a   Li, Xuhang ^a   Ming Tse, C ^a   Zachos, Nicholas C ^a   Donowitz, Mark ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; ION EXCHANGE; PROTEINS; SODIUM;

CO-IMMUNOPRECIPITATION ASSAYS; FLUORESCENCE RECOVERY; HETERODIMERIZATION; INTERACTION STRENGTH; MULTIPLE RECEPTORS; PHYSIOLOGICAL FUNCTIONS; REGULATORY FACTORS; SCAFFOLDING PROTEINS;

SCAFFOLDS (BIOLOGY);

ALPHA ACTININ 4; CARBACHOL; INTERFERON REGULATORY FACTOR; LIGAND; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE C ALPHA; PROTEIN ZO1; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 3;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHINESE HAMSTER; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HETERODIMERIZATION; HOMODIMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF;

DIMERIZATION; EPITHELIAL CELL; FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET); MACROCOMPLEX; MICROVILLUS; NHE3 (NA+/H+ EXCHANGER 3); NHERF PROTEINS; PROTEIN-PROTEIN INTERACTION; SCAFFOLD PROTEIN; TRAFFICKING;

AMINO ACID SUBSTITUTION; ANIMALS; CACO-2 CELLS; CARBACHOL; CELL LINE; CRICETINAE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PDZ DOMAINS; PHOSPHOPROTEINS; PROTEIN MULTIMERIZATION; RABBITS; RATS; RECOMBINANT FUSION PROTEINS; SODIUM-HYDROGEN ANTIPORTER;

EID: 84904497991     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.562413     Document Type: Article

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