A column-switching HPLC-MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders

Biomedical Chromatography

Volumn 28, Issue 8, 2014, Pages 1131-1139

  Gucciardi, Antonina ^a   Legnini, Elisa ^a   Di Gangi, Iole Maria ^a   Corbetta, Carlo ^b   Tomanin, Rosella ^a   Scarpa, Maurizio ^a   Giordano, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b V BUZZI CHILDREN S HOSPITAL   (Italy)

Author keywords

Column switching HPLC MS; Dried blood spot; Lysosomal storage disorders; MPS I; Newborn screening

Indexed keywords

BLOOD; DIAGNOSIS; ENZYME ACTIVITY; SCREENING;

COLUMN-SWITCHING HPLC; COLUMN-SWITCHING HPLC/MS; DRIED BLOOD SPOT; ENZYMES ACTIVITY; HPLC-MS; HPLC-MS-MS; LYSOSOMAL STORAGE DISORDER; MPS I; MULTIPLEX ASSAYS; NEWBORN SCREENING;

STEM CELLS;

LEVO IDURONIDASE;

ARTICLE; CONTROLLED STUDY; DRIED BLOOD SPOT TESTING; ENZYME ACTIVITY; FABRY DISEASE; GAUCHER DISEASE; GLOBOID CELL LEUKODYSTROPHY; GLYCOGEN STORAGE DISEASE TYPE 2; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HURLER SYNDROME; INFANT; LYSOSOME STORAGE DISEASE; NEWBORN SCREENING; NIEMANN PICK DISEASE; TANDEM MASS SPECTROMETRY; BLOOD; CASE CONTROL STUDY; ENZYME ASSAY; ENZYMOLOGY; LYSOSOMAL STORAGE DISEASES; METABOLISM; MUCOPOLYSACCHARIDOSIS I; NEWBORN; PROCEDURES; REPRODUCIBILITY; STATISTICAL MODEL;

CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRIED BLOOD SPOT TESTING; ENZYME ASSAYS; HUMANS; IDURONIDASE; INFANT, NEWBORN; LINEAR MODELS; LYSOSOMAL STORAGE DISEASES; MUCOPOLYSACCHARIDOSIS I; NEONATAL SCREENING; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84904468893     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3133     Document Type: Article

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