-
1
-
-
84861355868
-
Hepcidin and iron homeostasis
-
Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochim Biophys Acta. 2012;1823(9):1434-1443.
-
(2012)
Biochim Biophys Acta.
, vol.1823
, Issue.9
, pp. 1434-1443
-
-
Ganz, T.1
Nemeth, E.2
-
2
-
-
44449177930
-
The serine protease TMPRSS6 is required to sense iron deficiency
-
DOI 10.1126/science.1157121
-
Du X, She E, Gelbart T, et al. The serine protease TMPRSS6 is required to sense iron deficiency. Science. 2008;320(5879):1088-1092. (Pubitemid 351929552)
-
(2008)
Science
, vol.320
, Issue.5879
, pp. 1088-1092
-
-
Du, X.1
She, E.2
Gelbart, T.3
Truksa, J.4
Lee, P.5
Xia, Y.6
Khovananth, K.7
Mudd, S.8
Mann, N.9
Moresco, E.M.Y.10
Beutler, E.11
Beutler, B.12
-
3
-
-
56449096622
-
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
-
Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metab. 2008;8(6):502-511.
-
(2008)
Cell Metab.
, vol.8
, Issue.6
, pp. 502-511
-
-
Silvestri, L.1
Pagani, A.2
Nai, A.3
De Domenico, I.4
Kaplan, J.5
Camaschella, C.6
-
4
-
-
42649118442
-
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
-
DOI 10.1038/ng.130, PII NG130
-
Finberg KE, Heeney MM, Campagna DR, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008;40(5):569-571. (Pubitemid 351601217)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 569-571
-
-
Finberg, K.E.1
Heeney, M.M.2
Campagna, D.R.3
Aydinok, Y.4
Pearson, H.A.5
Hartman, K.R.6
Mayo, M.M.7
Samuel, S.M.8
Strouse, J.J.9
Markianos, K.10
Andrews, N.C.11
Fleming, M.D.12
-
5
-
-
84899837954
-
Iron and hepcidin: A story of recycling and balance
-
Camaschella C. Iron and hepcidin: a story of recycling and balance. Hematology Am Soc Hematol Educ Prog. 2013;2013:1-8.
-
(2013)
Hematology Am Soc Hematol Educ Prog.
, vol.2013
, pp. 1-8
-
-
Camaschella, C.1
-
6
-
-
70350482508
-
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
-
Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P. Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6. Br J Haematol. 2009;147(4):571-581.
-
(2009)
Br J Haematol.
, vol.147
, Issue.4
, pp. 571-581
-
-
Truksa, J.1
Gelbart, T.2
Peng, H.3
Beutler, E.4
Beutler, B.5
Lee, P.6
-
7
-
-
77952573858
-
Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis
-
Finberg KE, Whittlesey RL, Fleming MD, Andrews NC. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. Blood. 2010;115(18):3817-3826.
-
(2010)
Blood.
, vol.115
, Issue.18
, pp. 3817-3826
-
-
Finberg, K.E.1
Whittlesey, R.L.2
Fleming, M.D.3
Andrews, N.C.4
-
8
-
-
78751533321
-
Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6
-
Lenoir A, Deschemin JC, Kautz L, et al. Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6. Blood. 2011;117(2):647-650.
-
(2011)
Blood.
, vol.117
, Issue.2
, pp. 647-650
-
-
Lenoir, A.1
Deschemin, J.C.2
Kautz, L.3
-
9
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
DOI 10.1073/pnas.072632499
-
Nicolas G, Bennoun M, Porteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA. 2002;99(7):4596-4601. (Pubitemid 34286030)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.7
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
Mativet, S.4
Beaumont, C.5
Grandchamp, B.6
Sirito, M.7
Sawadogo, M.8
Kahn, A.9
Vaulont, S.10
-
10
-
-
0037174609
-
C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism: Cross-talk between C/EBP pathway and iron metabolism
-
DOI 10.1074/jbc.M202653200
-
Courselaud B, Pigeon C, Inoue Y, et al. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. J Biol Chem. 2002;277(43):41163-41170. (Pubitemid 35215708)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 41163-41170
-
-
Courselaud, B.1
Pigeon, C.2
Inoue, Y.3
Inoue, J.4
Gonzalez, F.J.5
Leroyer, P.6
Gilot, D.7
Boudjema, K.8
Guguen-Guillouzo, C.9
Brissot, P.10
Loreal, O.11
Ilyin, G.12
-
11
-
-
54349096688
-
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
-
Folgueras AR, de Lara FM, Pendás AM, et al. Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis. Blood. 2008;112(6):2539-2545.
-
(2008)
Blood.
, vol.112
, Issue.6
, pp. 2539-2545
-
-
Folgueras, A.R.1
De Lara, F.M.2
Pendás, A.M.3
-
12
-
-
84876539389
-
Role of hepcidin in the setting of hypoferremia during acute inflammation
-
Deschemin JC, Vaulont S. Role of hepcidin in the setting of hypoferremia during acute inflammation. PLoS ONE. 2013;8(4):e61050.
-
(2013)
PLoS ONE.
, vol.8
, Issue.4
-
-
Deschemin, J.C.1
Vaulont, S.2
-
14
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
DOI 10.1016/j.cmet.2005.01.003, PII S1550413105000306
-
Donovan A, Lima CA, Pinkus JL, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005;1(3):191-200. (Pubitemid 43960600)
-
(2005)
Cell Metabolism
, vol.1
, Issue.3
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
Pinkus, G.S.4
Zon, L.I.5
Robine, S.6
Andrews, N.C.7
-
15
-
-
79960848290
-
Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6)
-
Krijt J, Fujikura Y, Ramsay AJ, Velasco G, Nečas E. Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6). Blood Cells Mol Dis. 2011;47(2):133-137.
-
(2011)
Blood Cells Mol Dis.
, vol.47
, Issue.2
, pp. 133-137
-
-
Krijt, J.1
Fujikura, Y.2
Ramsay, A.J.3
Velasco, G.4
Nečas, E.5
-
16
-
-
84903578007
-
Identification of erythroferrone as an erythroid regulator of iron metabolism
-
published online ahead of print June 1, doi:10.1038/ng.2996
-
Kautz L, Jung G, Valore E, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism [published online ahead of print June 1, 2014]. Nat Genet. doi:10.1038/ng.2996.
-
(2014)
Nat Genet.
-
-
Kautz, L.1
Jung, G.2
Valore, E.3
Rivella, S.4
Nemeth, E.5
Ganz, T.6
-
17
-
-
78851471634
-
Is EPO therapy able to correct iron deficiency anaemia caused by matriptase-2 deficiency?
-
Nicolas G, Deschemin JC, Ramsay AJ, et al. Is EPO therapy able to correct iron deficiency anaemia caused by matriptase-2 deficiency? Br J Haematol. 2011;152(4):498-500.
-
(2011)
Br J Haematol.
, vol.152
, Issue.4
, pp. 498-500
-
-
Nicolas, G.1
Deschemin, J.C.2
Ramsay, A.J.3
|