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Volumn 124, Issue 3, 2014, Pages 441-444

Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

HEPCIDIN; IRON; MATRIPTASE; MATRIPTASE 2; SERINE PROTEINASE; UNCLASSIFIED DRUG;

EID: 84904464902     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-01-551150     Document Type: Article
Times cited : (29)

References (17)
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  • 3
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    • The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
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  • 5
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    • Camaschella, C.1
  • 6
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    • Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
    • Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P. Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6. Br J Haematol. 2009;147(4):571-581.
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  • 7
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    • Finberg KE, Whittlesey RL, Fleming MD, Andrews NC. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. Blood. 2010;115(18):3817-3826.
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  • 8
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    • Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6
    • Lenoir A, Deschemin JC, Kautz L, et al. Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6. Blood. 2011;117(2):647-650.
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  • 11
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    • Folgueras AR, de Lara FM, Pendás AM, et al. Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis. Blood. 2008;112(6):2539-2545.
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  • 12
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    • Role of hepcidin in the setting of hypoferremia during acute inflammation
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.