Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors

Stem Cells

Volumn 32, Issue 8, 2014, Pages 2178-2187

  Mitchell, Ryan ^a   Szabo, Eva ^a   Shapovalova, Zoya ^a   Aslostovar, Lili ^a   Makondo, Kennedy ^a   Bhatia, Mickie ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

OCT4; Reprogramming; Transdifferentiation

Indexed keywords

COMPLEMENT; OCTAMER TRANSCRIPTION FACTOR 4; CULTURE MEDIUM; POU5F1 PROTEIN, HUMAN;

ARTICLE; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; ENVIRONMENT; FIBROBLAST; GENE EXPRESSION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOLECULAR DYNAMICS; NEURAL STEM CELL; NUCLEAR REPROGRAMMING; PHENOTYPIC PLASTICITY; PLURIPOTENT STEM CELL; TRANSCRIPTION REGULATION; TRANSIENT EXPRESSION; AGING; CELL TRANSDIFFERENTIATION; CULTURE MEDIUM; CYTOLOGY; DNA MICROARRAY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; METABOLISM; PHARMACOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; STEM CELL;

AGING; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CELLULAR REPROGRAMMING; CULTURE MEDIA, CONDITIONED; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; OCTAMER TRANSCRIPTION FACTOR-3; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; STEM CELLS;

EID: 84904437964     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1721     Document Type: Article

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