Validation of EUCAST zone diameter breakpoints against reference broth microdilution

Clinical Microbiology and Infection

Volumn 20, Issue 6, 2014, Pages

  Bengtsson, S ^a   Bjelkenbrant, C ^a   Kahlmeter, G ^a,b  

^a CENTRAL HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Antimicrobial susceptibility testing; Broth microdilution; Disc diffusion; EUCAST clinical breakpoints; EUCAST disc diffusion method

Indexed keywords

AMPICILLIN; AZTREONAM; CEFEPIME; CEFOXITIN; CEFTAZIDIME; CEFUROXIME; CIPROFLOXACIN; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; IMIPENEM; LINEZOLID; MEROPENEM; MOXIFLOXACIN; NITROFURANTOIN; PENICILLIN G; PIPERACILLIN PLUS TAZOBACTAM; TEICOPLANIN; TETRACYCLINE; TIGECYCLINE; TOBRAMYCIN; TRIMETHOPRIM; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BROTH DILUTION; COAGULASE NEGATIVE STAPHYLOCOCCUS; DISK DIFFUSION; ENTEROBACTER AEROGENES; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ENTEROBACTERIACEAE; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MORGANELLA MORGANII; NONHUMAN; PRIORITY JOURNAL; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; REFERENCE VALUE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS LUGDUNENSIS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; VALIDATION STUDY; VANCOMYCIN RESISTANT ENTEROCOCCUS; COMPARATIVE STUDY; DRUG EFFECTS; EUROPE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; MICROBIAL SENSITIVITY TEST; PROCEDURES; STANDARDS;

NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; EUROPE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; MICROBIAL SENSITIVITY TESTS;

EID: 84904421637     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12414     Document Type: Article

References (11)

1. Kahlmeter G, Brown DFJ, Goldstein FW et al. European Committee on Antimicrobial Susceptibility Testing (EUCAST) technical notes on antimicrobial susceptibility testing. Clin Microbiol Infect 2006; 12: 501-503.
2. Matuschek E, Brown DFJ, Kahlmeter G. Development of the EUCAST disk diffusion antimicrobial susceptibility testing method and its implementation in routine microbiology laboratories. Clin Microbiol Infect doi: 10.1111/1469-0691.
3. The European Committee on Antimicrobial Susceptibility Testing. Antimicrobial Susceptibility Testing. Calibration and Validation. http://www.eucast.org, last accessed August 26 2013.
4. ISO 20776-1. Clinical laboratory testing and in vitro diagnostic test systems-Susceptibility testing of infectious agents and evolution of performance of antimicrobial susceptibility test devices. Part 1: Reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases. 2006.
5. ISO 20776-2. Clinical laboratory testing and in vitro diagnostic test systems- Susceptibility testing of infectious agents and evolution of performance of antimicrobial susceptibility test devices. Part 2: Evaluation of performance of antimicrobial susceptibility test devices. 2007.
6. European Committee on Antimicrobial Susceptibility Testing. Breakpoint tables for interpretation of MICs and zone diameters. Version 2.0, 2012. http://www.eucast.org
7. Arendrup M, Kahlmeter G, Rodriguez-Tudela J et al. Breakpoints for susceptibility testing should not divide wild-type distribution of important target species. Antimicrob Agents Chemother 2009; 53: 1628-1629.
8. Kahlmeter G, Brown DFJ. Harmonization of antimicrobial breakpoints in Europe-can it be achieved? Clin Microbiol Newsl 2004; 26: 187-192.
9. Kronvall G, Giske C, Kahlmeter G. Setting interpretive breakpoints for antimicrobial susceptibility testing using disk diffusion. Int J Antimicrob Agents 2011; 38: 281-290.
10. Hombach M, Böttger E, Roos M. The critical influence of the intermediate category on interpretation errors in revised EUCAST and CLSI antimicrobial susceptibility testing guidelines. Clin Microbiol Infect 2013; 2: E59-E71.
11. Kaase M, Lenga S, Friedrich S et al. Comparison of phenotypic methods for penicillinase detection in Staphylococcus aureus. Clin Microbiol Infect 2008; 14: 614-618.