The effects of lobeline on nicotine withdrawal-induced depression-like behavior in mice

Psychopharmacology

Volumn 231, Issue 15, 2014, Pages 2989-2998

  Roni, Monzurul Amin ^a   Rahman, Shafiqur ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

BDNF; Depression; Lobeline; Mice; Nicotine addiction; Nicotinic receptor; Norepinephrine

Indexed keywords

3 (PYRIDIN 3 YL)CYTISINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYSTEINE DERIVATIVE; LOBELINE; NORADRENALIN; UNCLASSIFIED DRUG; ANTIDEPRESSANT AGENT; COTININE; CREB1 PROTEIN, MOUSE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG TARGETING; FORCED SWIM TEST; HIPPOCAMPUS; MALE; MOUSE; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC SYSTEM; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOKING CESSATION; TOBACCO DEPENDENCE; UPREGULATION; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; METABOLISM; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; SUBSTANCE WITHDRAWAL SYNDROME; SWIMMING;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; COTININE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DEPRESSION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; LOBELINE; MALE; MICE, INBRED C57BL; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TESTS; NICOTINE; NICOTINIC AGONISTS; NOREPINEPHRINE; PREFRONTAL CORTEX; RECEPTORS, NICOTINIC; SUBSTANCE WITHDRAWAL SYNDROME; SWIMMING; TOBACCO USE DISORDER;

EID: 84904418580     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-014-3472-y     Document Type: Article

References (57)

1. Andreasen JT, Nielsen EØ, Redrobe JP (2009) Chronic oral nicotine increases brain [3H] epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim test. Psychopharmacology (Berl) 205:517-528
2. Bell RL, Eilier BA, Cook JB, Rahman S (2009) Nicotinic receptor ligands reduce ethanol intake by high alcohol-drinking HAD-2 rats. Alcohol 43:581-592
3. Benowitz NL (2010) Nicotine addiction. N Engl J Med 362:2295-2303
4. Bhang SY, Choi SW, Ahn JH (2010) Changes in plasma brain-derived neurotrophic factor levels in smokers after smoking cessation. Neurosci Lett 468:7-11
5. Brunzell DH, Russell DS, PicciottoMR(2003) In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice. J Neurochem 84:1431-1441 (Pubitemid 36343609)
6. Campbell S, MacQueen G (2004) The role of the hippocampus in the pathophysiology of major depression. J Psychiatry Neurosci 29:417-426 (Pubitemid 40075713)
7. Chen MJ, Nguyen TV, Pike CJ, Russo-Neustadt AA (2007) Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons. Cell Signal 19:114-128 (Pubitemid 44880248)
8. Damaj M, Patrick G, Creasy K, Martin B (1997) Pharmacology of lobeline, a nicotinic receptor ligand. J Pharmacol Exp Ther 282:410-419 (Pubitemid 27425569)
9. Duman RS, Aghajanian GK (2012) Synaptic dysfunction in depression: potential therapeutic targets. Science 338:68-72
10. Dwoskin LP, Crooks PA (2002) A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse. Biochem Pharmacol 63:89-98 (Pubitemid 34158807)
11. Filip M, Faron-Górecka A, Kuśmider M, Gołda A, Frankowska M, Dziedzicka-Wasylewska M (2006) Alterations in BDNF and trkB mRNAs following acute or sensitizing cocaine treatments and withdrawal. Brain Res 1071:218-225 (Pubitemid 43255491)
12. Franklin KBG, Paxinos G (2007) The mouse brain in stereotaxic coordinates, 3rd edn. Academic Press, Inc., New York
13. Gäddnäs H, Pietilä K, Ahtee L (2000) Effects of chronic oral nicotine treatment and its withdrawal on locomotor activity and brain monoamines in mice. Behav Brain Res 113:65-72 (Pubitemid 30645544)
14. 3H]norepinephrine from fetal rat locus coeruleus cells in culture. J Neurochem 70:663-670
15. George MS, Ketter TA, Post RM (1994) Prefrontal cortex dysfunction in clinical depression. Depression 2:59-72
16. Glover ED, Leischow SJ, Rennard SI, Glover PN, Daughton D, Quiring JN, Schneider FH, Mione PJ (1998) A smoking cessation trial with lobeline sulfate: a pilot study. Am J Health Behav 22:62-74
17. Grabus S, Martin B, Imad DamajM(2005) Nicotine physical dependence in the mouse: involvement of the α7 nicotinic receptor subtype. Eur J Pharmacol 515:90-93 (Pubitemid 40779272)
18. Grimm JW, Lu L, Hayashi T, Hope BT, Su TP, Shaham Y (2003) Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J Neurosci 23:742-747 (Pubitemid 36206164)
19. Harrod SB, Van Horn ML (2009) Sex differences in tolerance to the locomotor depressant effects of lobeline in periadolescent rats. Pharmacol Biochem Behav 94:296-304
20. Harrod SB, Dwoskin LP, Crooks PA, Klebaur JE, Bardo MT (2001) Lobeline attenuates d-methamphetamine self-administration in rats. J Pharmacol Exp Ther 298:172-179 (Pubitemid 32574524)
21. Hughes, J.R., Stead, L.F., Lancaster, T. (2007) Antidepressants for smoking cessation. Cochrane Database Syst Rev 1:CD000031.
22. Jackson KJ, Martin BR, Changeux JP, Damaj MI (2008) Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. J Pharmacol Exp Ther 325:302-312 (Pubitemid 351439184)
23. Jackson KJ, McIntosh JM, Brunzell DH, Sanjakdar SS, Damaj MI (2009) The role of α6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal. J Pharmacol Exp Ther 331:547-554
24. Kim TS, KimDJ, Lee H, Kim YK (2007) Increased plasma brain-derived neurotrophic factor levels in chronic smokers following unaided smoking cessation. Neurosci Lett 423:53-57 (Pubitemid 47176776)
25. Kivinummi T, Kaste K, Rantamäki T, Castrén E, Ahtee L (2011) Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice. Neurosci Lett 491:108-112
26. Klein LC, StineMM, Vandenbergh DJ, Whetzel CA, Kamens HM (2004) Sex differences in voluntary oral nicotine consumption by adolescent mice: a dose-response experiment. Pharmacol Biochem Behav 78:13-25 (Pubitemid 38670509)
27. Krishnan V, Nestler EJ (2008) The molecular neurobiology of depression. Nature 455:894-902
28. Mannucci C, TedescoM, BellomoM, Caputi A, Calapai G (2006) Long-term effects of nicotine on the forced swimming test in mice: an experimental model for the study of depression caused by smoke. Neurochem Int 49:481-486 (Pubitemid 44209297)
29. McClung CA, Nestler EJ (2007) Neuroplasticity mediated by altered gene expression. Neuropsychopharmacology 33:3-17
30. 3H]dopamine overflow from rat striatal slices and nicotine-evoked 86Rb+ efflux from thalamic synaptosomes. Neuropharmacology 39:2654-2662
31. Miller DK, Crooks PA, Teng L, Witkin JM, Munzar P, Goldberg SR, Acri JB, Dwoskin LP (2001) Lobeline inhibits the neurochemical and behavioral effects of amphetamine. J Pharmacol Exp Ther 296:1023-1034 (Pubitemid 32187378)
32. Miller DK, Harrod SB, Green TA, Wong MY, Bardo MT, Dwoskin LP (2003) Lobeline attenuates locomotor stimulation induced by repeated nicotine administration in rats. Pharmacol Biochem Behav 74:279-286 (Pubitemid 35449513)
33. Mineur YS, Eibl C, Young G, Kochevar C, Papke RL, Gündisch D, Picciotto MR (2009) Cytisine-based nicotinic partial agonists as novel antidepressant compounds. J Pharmacol Exp Ther 329:377-386
34. Nguyen HN, Rasmussen BA, Perry DC (2003) Subtype-selective upregulation by chronic nicotine of high-affinity nicotinic receptors in rat brain demonstrated by receptor autoradiography. J Pharmacol Exp Ther 307:1090-1097 (Pubitemid 37494228)
35. Parker MJ, Beck A, Luetje CW (1998) Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity. Mol Pharmacol 54:1132-1139 (Pubitemid 29002059)
36. Pietilä K, Laakso I, Ahtee L (1995) Chronic oral nicotine administration affects the circadian rhythm of dopamine and 5-hydroxytryptamine metabolism in the striata of mice. Naunyn-Schmiedeberg Arch Pharmacol 353:110-115 (Pubitemid 26009069)
37. Porsolt RD, Le Pichon M, Jalfre M (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature 266:730-732 (Pubitemid 8073804)
38. Rabenstein RL, Caldarone BJ, Picciotto MR (2006) The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacology (Berl) 189:395-401 (Pubitemid 44772820)
39. Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT (2008) The novel nicotinic receptor antagonist N,N′-dodecane-1,12-diyl-bis-3- picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens. Eur J Pharmacol 601:103-105
40. Ressler KJ, Nemeroff CB (2000) Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders. Depress Anxiety 12:2-19
41. Ribeiro-Carvalho A, Lima CS, Medeiros AH, Siqueira NR, Filgueiras CC, Manhaes AC, Abreu-Villaça Y (2009) Combined exposure to nicotine and ethanol in adolescent mice: effects on the central cholinergic systems during short and long term withdrawal. Neurosci 162:1174-1186
42. Robinson SF, Marks MJ, Collins AC (1996) Inbred mouse strains vary in oral self-selection of nicotine. Psychopharmacology (Berl) 124:332-339 (Pubitemid 26147147)
43. Roni MA, Rahman S (2011) Neuronal nicotinic receptor antagonist reduces anxiety-like behavior in mice. Neurosci Lett 504:237-241
44. Roni MA, Rahman S (2013) Antidepressant-like effects of lobeline in mice: behavioral, neurochemical, and neuroendocrine evidence. Prog Neuropsychopharmacol Biol Psychiatry 41:44-51
45. Sajja RK, Rahman S (2011) Lobeline and cytisine reduce voluntary ethanol drinking behavior in male C57BL/6J mice. Prog Neuro-Psychopharmacol Biol Psychiatry 35:257-264
46. Sajja RK, Rahman S (2012)Neuronal nicotinic receptor ligandsmodulate chronic nicotine-induced ethanol consumption in C57BL/6J mice. Pharmacol Biochem Behav 102:36-43
47. Sajja RK, Dwivedi C, Rahman S (2010) Nicotinic ligands modulate ethanol-induced dopamine function in mice. Pharmacology 86:168-173
48. Salas R, Pieri F, De Biasi M (2004) Decreased signs of nicotine withdrawal in mice null for the β4 nicotinic acetylcholine receptor subunit. J Neurosci 24:10035-10039 (Pubitemid 39492026)
49. Sanberg PR, Vindrola-Padros C, Shytle RD (2012) Translating laboratory discovery to the clinic: from nicotine and mecamylamine to tourettes, depression, and beyond. Physiology Behav 107:801-808
50. Semba J, Wakuta M, Maeda J, Suhara T (2004) Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation. Psychoneuroendocrinology 29:215-226 (Pubitemid 37357180)
51. Sparks JA, Pauly JR (1999) Effects of continuous oral nicotine administration on brain nicotinic receptors and responsiveness to nicotine in C57Bl/6 mice. Psychopharmacology (Berl) 14:145-153 (Pubitemid 29200165)
52. Stolerman IP, Garcha HS, Mirza NR (1995) Dissociations between the locomotor stimulant and depressant effects of nicotinic agonists in rats. Psychopharmacology (Berl) 117:430-437
53. Tani Y, Saito K, Tsuneyoshi A, Imoto M, Ohno T (1997) Nicotinic acetylcholine receptor (nACh-R) agonist-induced changes in brain monoamine turnover in mice. Psychopharmacology (Berl) 129:225-232 (Pubitemid 27085392)
54. Watkins SS, Stinus L, Koob GF, Markou A (2000) Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. J Pharmacol Exp Ther 292:1053-1064 (Pubitemid 30136601)
55. Wilkinson JL, Palmatier MI, Bevins RA (2006) Preexposure to nicotine alters the subsequent locomotor stimulant effects of bupropion in rats. Nicotine Tob Res 8:141-146
56. Xu Y, Ku B, Tie L, Yao H, Jiang W, Ma X, Li X (2006) Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. Brain Res 1122:56-64 (Pubitemid 44708120)
57. Zaniewska M, McCreary AC, Wydra K, Filip M (2010) Effects of serotonin 5-HT 2 receptor ligands on depression-like behavior during nicotine withdrawal. Neuropharmacology 58:1140-1146