Urinary tract infection in small outpatient children: The influence of age and gender on resistance to oral antimicrobials

European Journal of Pediatrics

Volumn 173, Issue 8, 2014, Pages 1075-1081

  Swerkersson, Svante ^a   Jodal, Ulf ^a   Åhrén, Christina ^b,c   Hansson, Sverker ^a  

^a QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c STRAMA Swedish Strategic Programme Against Antibiotic Resistance   (Sweden)

Author keywords

Antibiotic resistance; Children; Urinary tract infection; Vesicoureteral reflux

Indexed keywords

ANTIINFECTIVE AGENT; CEFADROXIL; NITROFURANTOIN; TRIMETHOPRIM;

AGE DISTRIBUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CHILD; CLINICAL ARTICLE; ESCHERICHIA COLI; FEMALE; HUMAN; MALE; NONHUMAN; OUTPATIENT; PEDIATRICS; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SEX DIFFERENCE; TREATMENT DURATION; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; AGE; BACTERIAL INFECTIONS; ESCHERICHIA COLI INFECTIONS; INFANT; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; URINARY TRACT INFECTIONS;

AGE FACTORS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; INFANT; MALE; MICROBIAL SENSITIVITY TESTS; OUTPATIENTS; RETROSPECTIVE STUDIES; SEX FACTORS; URINARY TRACT INFECTIONS;

EID: 84904417059     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-014-2289-3     Document Type: Article

References (32)

1. Abelson Storby K, Osterlund A, Kahlmeter G (2004) Antimicrobial resistance in Escherichia coli in urine samples from children and adults: a 12 year analysis. Acta Paediatr 93:487-491 (Pubitemid 38469696)
2. Allen UD, MacDonald N, Fuite L, Chan F, Stephens D (1999) Risk factors for resistance to "first-line" antimicrobials among urinary tract isolates of Escherichia coli in children. CMAJ 160:1436-1440 (Pubitemid 29248428)
3. Bean DC, Krahe D, Wareham DW (2008) Antimicrobial resistance in community and nosocomial Escherichia coli urinary tract isolates, London 2005-2006. Ann Clin Microbiol Antimicrob 7:13. doi:10.1186/1476-0711-7-13
4. Birgy A, Cohen R, Levy C, Bidet P, Courroux C, Benani M, Thollot F, Bingen E (2012) Community faecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in French children. BMC Infect Dis 12:315. doi:10.1186/1471-2334-12-315
5. Cullen IM, Manecksha RP, McCullagh E, Ahmad S, O'Kelly F, Flynn RJ, McDermott T, Murphy P, Grainger R, Fennell JP, Thornhill JA (2012) The changing pattern of antimicrobial resistance within 42,033 Escherichia coli isolates from nosocomial, community and urology patient-specific urinary tract infections, Dublin, 1999-2009. BJU Int 109:1198-1206. doi:10.1111/j.1464-410X.2011.10528.x
6. Edlin R, Shapiro D, Hersh A, Copp H (2013) Antibiotic resistance patterns of outpatient pediatric urinary tract infections. J Urol 190: 222-227, doi: 0.1016/j.juro.2013.01.069
7. Gaspari RJ, Dickson E, Karlowsky J, Doern G (2005) Antibiotic resistance trends in paediatric uropathogens. Int J Antimicrob Agents 26:267-271 (Pubitemid 41341395)
8. Gupta K, Scholes D, Stamm WE (1999) Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women. JAMA 281:736-738 (Pubitemid 29113455)
9. Hakansson A, Petersson C (1992) Drug consumption during the first 18months of life of infants from smoking and non-smoking families. Br J Gen Pract 42:362-365
10. Hanson LA (1976) Esch. coli infections in childhood. Significance of bacterial virulence and immune defence. Arch Dis Child 51:737-743
11. Helldal L, Karami N, Floren K, Welinder-Olsson C, Moore ER, Ahren C (2013) Shift of CTX-M genotypes has determined the increased prevalence of extended-spectrum beta-lactamaseproducing Escherichia coli in south-western Sweden. Clin Microbiol Infect 19:E87-E90. doi:10.1111/1469-0691.12086
12. Hellerstein S (1998) Urinary tract infections in children: why they occur and how to prevent them. Am Fam Physician 57(2440-6):2452-2454
13. Hoberman A, Wald ER, Hickey RW, Baskin M, Charron M, Majd M, Kearney DH, Reynolds EA, Ruley J, Janosky JE (1999) Oral versus initial intravenous therapy for urinary tract infections in young febrile children. Pediatrics 104:79-86 (Pubitemid 29315851)
14. Jacobson SH, Eklof O, Eriksson CG, Lins LE, Tidgren B, Winberg J (1989) Development of hypertension and uraemia after pyelonephritis in childhood: 27 year follow up. BMJ 299:703-706 (Pubitemid 19235914)
15. Jantunen ME, Siitonen A, Ala-Houhala M, Ashorn P, Föhr A, Koskimies O, Wikström S, Saxén H (2001) Predictive factors associated with significant urinary tract abnormalities in infants with pyelonephritis. Pediatr Infect Dis J 20:597-601 (Pubitemid 32567721)
16. Jodal U, Winberg J (1987) Management of children with unobstructed urinary tract infection. Pediatr Nephrol 1:647-656 (Pubitemid 18014583)
17. Kanellopoulos TA, Salakos C, Spiliopoulou I, Ellina A, Nikolakopoulou NM, Papanastasiou DA (2006) First urinary tract infection in neonates, infants and young children: a comparative study. Pediatr Nephrol 21:1131-1137 (Pubitemid 44083887)
18. Lagacé-Wiens PR, Simner PJ, Forward KR, Tailor F, Adam HJ, Decorby M, Karlowsky J, Hoban DJ, Zhanel GG (2011) Canadian Antimicrobial Resistance Alliance (CARA). Analysis of 3789 in. and outpatient Escherichia coli isolates from across Canada-results of the CANWARD 2007-2009 study. Diagn Microbiol Infect Dis 69(3):314-319. doi:10.1016/j.diagmicrobio.2010.10.027
19. Lebowitz RL, Olbing H, Parkkulainen KV, Smellie JM, Tamminen- Mobius TE (1985) International system of radiographic grading of vesicoureteric reflux. International Reflux Study in Children. Pediatr Radiol 15:105-109 (Pubitemid 15198933)
20. Marild S, Jodal U (1998) Incidence rate of first-time symptomatic urinary tract infection in children under 6 years of age. Acta Paediatr 87:549-552 (Pubitemid 28257296)
21. Martinell J, Jodal U, Lidin-Janson G (1990) Pregnancies in women with and without renal scarring after urinary infections in childhood. BMJ 300:840-844 (Pubitemid 20113346)
22. McGregor JC, Elman MR, Bearden DT, Smith DH (2013) Sex- and age-specific trends in antibiotic resistance patterns of Escherichia coli urinary isolates from outpatients. BMC Fam Pract 14:25. doi:10.1186/1471-2296-14-25
23. Mölstad S, Cars O, Struwe J (2008) Strama - a Swedish working model for containment of antibiotic resistance. Euro Surveill 13(46). doi:pii:19041
24. Mölstad S, Erntell M, Hanberger H, Melander E, Norman C, Skoog G, Lundborg CS, Söderström A, Torell E, Cars O (2008) Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme. Lancet Infect Dis 8:125-132. doi:10.1016/S1473- 3099(08)70017-3
25. Patzer L, Seeman T, Luck C, Wuhl E, Janda J, Misselwitz J (2003) Day- and night-time blood pressure elevation in children with higher grades of renal scarring. J Pediatr 142:117-122 (Pubitemid 36232898)
26. Prelog M, Schiefecker D, Fille M, Wurzner R, Brunner A, Zimmerhackl LB (2008) Febrile urinary tract infection in children: ampicillin and trimethoprim insufficient as empirical mono-therapy. Pediatr Nephrol 23:597-602. doi:10.1007/s00467-007-0701-1
27. Ragnarsdottir B, Svanborg C (2012) Susceptibility to acute pyelonephritis or asymptomatic bacteriuria: host-pathogen interaction in urinary tract infections. Pediatr Nephrol 27:2017-2029. doi:10.1007/s00467-011-2089-1 27:2017-29
28. Ransley PG, Risdon RA (1981) Reflux nephropathy: effects of antimicrobial therapy on the evolution of the early pyelonephritic scar. Kidney Int 20:733-742 (Pubitemid 12169009)
29. Swedish Reference Group of Antibiotics (1997) Antimicrobial susceptibility testing in Sweden. Scand J Infect Dis Suppl 105:5-31
30. Swedish Institute for Infectious Disease Control. Smittskyddsinstitutet. http://www.smittskyddsinstitutet.se/publikationer/arsrapporteroch- verksamhetsberattelser/swedres/swedres-2003/. Accessed 19 Nov 2013
31. Swedish Institute for Infectious Disease Control. Smittskyddsinstitutet. http://www.smittskyddsinstitutet.se/publikationer/arsrapporter- ochverksamhetsberattelser/swedres/swedresswarm-2012/. Accessed 19 Nov 2013
32. Yüksel S, Oztürk B, Kavaz A, Ozçakar ZB, Acar B, Güriz H, Aysev D, Ekim M, Yalçinkaya F (2006) Antibiotic resistance of urinary tract pathogens and evaluation of empirical treatment in Turkish children with urinary tract. Int J Antimicrob Agents 28:413-416