Gene mutation analysis in a korean patient with early-onset and recalcitrant generalized pustular psoriasis

Annals of Dermatology

Volumn 26, Issue 3, 2014, Pages 424-425

  Song, Hyo Sang ^a   Yun, Su Jin ^a   Park, Sun ^a   Lee, Eun So ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84904353423     PISSN: 10139087     EISSN: 20053894     Source Type: Journal    
DOI: 10.5021/ad.2014.26.3.424     Document Type: Letter

References (5)

1. Griffiths CE, Barker JN. Pathogenesis and clinical features of psoriasis. Lancet 2007;370:263-271. (Pubitemid 47069537)
2. Marrakchi S, Guigue P, Renshaw BR, Puel A, Pei XY, Fraitag S, et al. Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med 2011;365:620-628.
3. Onoufriadis A, Simpson MA, Pink AE, Di Meglio P, Smith CH, Pullabhatla V, et al. Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis. Am J Hum Genet 2011;89:432-437.
4. Farooq M, Nakai H, Fujimoto A, Fujikawa H, Matsuyama A, Kariya N, et al. Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis. Hum Mutat 2013;34:176-183.
5. Debets R, Timans JC, Homey B, Zurawski S, Sana TR, Lo S, et al. Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. J Immunol 2001;167:1440-1446. (Pubitemid 32703142)