Dabigatran etexilate linked to fatal gastrointestinal hemorrhage

Israel Medical Association Journal

Volumn 16, Issue 6, 2014, Pages 388-389

  Feinberg, Joshua ^a   Grabowitz, Laurel ^a   Rotman Pikielny, Pnina ^a   Berla, Maya ^a   Levy, Yair ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Atrial fibrillation; Dabigatran etexilate; Elderly; Gastrointestinal hemorrhage; Prolonged prothrombin time

Indexed keywords

AGED, 80 AND OVER; ANTITHROMBINS; BENZIMIDAZOLES; FATAL OUTCOME; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; PROTHROMBIN TIME; PYRIDINES;

EID: 84904313622     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (5)

1. Connolly SJ, Ezekowitz MD, Yusuf S, et al., RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361: 1139-51.
2. Weitz JI, Quinlan DJ, Eikelboom JW. Periprocedural management and approach to bleeding in patients taking dabigatran. Circulation 2012; 126: 2428-32.
3. Béné J, Saïd W, Rannou M, Deheul S, Coupe P, Gautier S. Rectal bleeding and hemostatic disorders induced by dabigatran etexilate in 2 elderly patients. Ann Pharmacother 2012; 46: 14.
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5. van Ryn J, Stangier J, Haertter S, et al. Dabigatran etexilate: a novel, reversible, oral direct thrombin inhibitor-interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010; 103: 1116-27.