메뉴 건너뛰기




Volumn 241, Issue , 2014, Pages

Unintentional lethal overdose with metildigoxin in a 36-week-old infant - post mortem tissue distribution of metildigoxin and its metabolites by liquid chromatography tandem mass spectrometry

Author keywords

Cardiac glycosides; Digoxin; Mass spectrometry; Metildigoxin; Overdose

Indexed keywords

2 ETHYLIDEN 1,5 DIMETHYL 3,3 DIPHENYL PYRROLIDIN; BETA METILDIGOXIN; DIGOXIN; DIGOXINGENIN; DIGOXINGENIN MONODIGITOXOSID; DRUG METABOLITE; METHADONE; METILDIGOXIN; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; DIGOXIGENIN; DIGOXIGENIN-MONO(DIGITOXOSIDE);

EID: 84904304555     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2014.05.013     Document Type: Article
Times cited : (3)

References (25)
  • 1
    • 34548639939 scopus 로고    scopus 로고
    • Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization/tandem mass spectrometry
    • Mitamura K., Horikawa A., Yamane Y., Ikeda Y., Fujii Y., Shimada K. Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization/tandem mass spectrometry. Biol. Pharm. Bull. 2007, 30:1653-1656.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 1653-1656
    • Mitamura, K.1    Horikawa, A.2    Yamane, Y.3    Ikeda, Y.4    Fujii, Y.5    Shimada, K.6
  • 2
    • 82955225903 scopus 로고    scopus 로고
    • Analysis of digoxin and metildigoxin in whole blood using solid-phase extraction and liquid chromatography tandem mass spectrometry
    • Melo P., Machado R., Teixeira H.M. Analysis of digoxin and metildigoxin in whole blood using solid-phase extraction and liquid chromatography tandem mass spectrometry. Int. J. Anal. Chem. 2012, 975824.
    • (2012) Int. J. Anal. Chem. , pp. 975824
    • Melo, P.1    Machado, R.2    Teixeira, H.M.3
  • 3
    • 33745792137 scopus 로고    scopus 로고
    • An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites
    • Musshoff F., Trafkowski J., Kuepper U., Madea B. An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites. J. Mass Spectrom. 2006, 41:633-640.
    • (2006) J. Mass Spectrom. , vol.41 , pp. 633-640
    • Musshoff, F.1    Trafkowski, J.2    Kuepper, U.3    Madea, B.4
  • 4
    • 0026254542 scopus 로고
    • Serum digoxin in children treated with beta methyl digoxin
    • Soler P., Garcia Y., Zilleruelo R. Serum digoxin in children treated with beta methyl digoxin. Rev. Chil. Pediatr. 1991, 62:350-354.
    • (1991) Rev. Chil. Pediatr. , vol.62 , pp. 350-354
    • Soler, P.1    Garcia, Y.2    Zilleruelo, R.3
  • 5
    • 0019376281 scopus 로고
    • Pharmacokinetics of beta-methyldigoxin and beta-acetyldigoxin in patients with cirrhosis of the liver
    • Rameis H., Bonelli J., Waginger H., Hruby K. Pharmacokinetics of beta-methyldigoxin and beta-acetyldigoxin in patients with cirrhosis of the liver. Wien. Klin. Wochenschr. 1981, 93:572-576.
    • (1981) Wien. Klin. Wochenschr. , vol.93 , pp. 572-576
    • Rameis, H.1    Bonelli, J.2    Waginger, H.3    Hruby, K.4
  • 6
    • 0037453950 scopus 로고    scopus 로고
    • Association of serum digoxin concentration and outcomes in patients with heart failure
    • Rathore S.S., Curtis J.P., Wang Y., Bristow M.R., Krumholz H.M. Association of serum digoxin concentration and outcomes in patients with heart failure. J. Am. Med. Assoc. 2003, 19(289):871-878.
    • (2003) J. Am. Med. Assoc. , vol.19 , Issue.289 , pp. 871-878
    • Rathore, S.S.1    Curtis, J.P.2    Wang, Y.3    Bristow, M.R.4    Krumholz, H.M.5
  • 7
    • 0032868693 scopus 로고    scopus 로고
    • Therapeutic range of digoxin's efficacy in heart failure: what is the evidence?
    • Terra S.G., Washam J.B., Dunham G.D., Gattis W.A. Therapeutic range of digoxin's efficacy in heart failure: what is the evidence?. Pharmacotherapy 1999, 19:1123-1126.
    • (1999) Pharmacotherapy , vol.19 , pp. 1123-1126
    • Terra, S.G.1    Washam, J.B.2    Dunham, G.D.3    Gattis, W.A.4
  • 8
    • 0015818991 scopus 로고
    • Comparative bioavailability of two oral preparations of digoxin in healthy volunteers
    • Panisset J.C., Biron P., Tremblay G., Nadeau R., Proulx A. Comparative bioavailability of two oral preparations of digoxin in healthy volunteers. Can. Med. Assoc. J. 1973, 109:700-702.
    • (1973) Can. Med. Assoc. J. , vol.109 , pp. 700-702
    • Panisset, J.C.1    Biron, P.2    Tremblay, G.3    Nadeau, R.4    Proulx, A.5
  • 9
    • 0037453950 scopus 로고    scopus 로고
    • Association of serum digoxin concentration and outcomes in patients with heart failure
    • Rathore S.S., Curtis J.P., Wang Y., Bristow M.R., Krumholz H.M. Association of serum digoxin concentration and outcomes in patients with heart failure. J. Am. Med. Assoc. 2003, 19(289):871-878.
    • (2003) J. Am. Med. Assoc. , vol.19 , Issue.289 , pp. 871-878
    • Rathore, S.S.1    Curtis, J.P.2    Wang, Y.3    Bristow, M.R.4    Krumholz, H.M.5
  • 10
    • 0026254542 scopus 로고
    • Serum digoxin in children treated with beta methyl digoxin
    • Soler P., Garcia Y., Zilleruelo R., et al. Serum digoxin in children treated with beta methyl digoxin. Rev. Chil. Pediatr. 1991, 62:350-354.
    • (1991) Rev. Chil. Pediatr. , vol.62 , pp. 350-354
    • Soler, P.1    Garcia, Y.2    Zilleruelo, R.3
  • 11
    • 0014900563 scopus 로고
    • Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration
    • Smith T.W., Haber E. Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration. J. Clin. Invest. 1970, 49:2377-2386.
    • (1970) J. Clin. Invest. , vol.49 , pp. 2377-2386
    • Smith, T.W.1    Haber, E.2
  • 12
    • 13144264943 scopus 로고    scopus 로고
    • Digoxin toxicity: pediatric survival after asystolic arrest
    • Eyal D., Molczan K.A., Carroll L.S. Digoxin toxicity: pediatric survival after asystolic arrest. Clin. Toxicol. (Phila.) 2005, 43:51-54.
    • (2005) Clin. Toxicol. (Phila.) , vol.43 , pp. 51-54
    • Eyal, D.1    Molczan, K.A.2    Carroll, L.S.3
  • 13
    • 0015917167 scopus 로고
    • Digoxin serum half-life following suicidal digoxin poisoning
    • Hobson J.D., Zettner A. Digoxin serum half-life following suicidal digoxin poisoning. J. Am. Med. Assoc. 1973, 223:147-149.
    • (1973) J. Am. Med. Assoc. , vol.223 , pp. 147-149
    • Hobson, J.D.1    Zettner, A.2
  • 14
    • 0021885641 scopus 로고
    • Digoxin toxicity presenting with psychosis in a patient with chronic phobic anxiety
    • Carney M.W., Rapp S., Pearce K. Digoxin toxicity presenting with psychosis in a patient with chronic phobic anxiety. Clin. Neuropharmacol. 1985, 8:193-195.
    • (1985) Clin. Neuropharmacol. , vol.8 , pp. 193-195
    • Carney, M.W.1    Rapp, S.2    Pearce, K.3
  • 16
    • 0014884416 scopus 로고
    • Tritiated digoxin. XIV. Enterohepatic circulation, absorption, and excretion studies in human volunteers
    • Doherty J.E., Flanigan W.J., Murphy M.L., et al. Tritiated digoxin. XIV. Enterohepatic circulation, absorption, and excretion studies in human volunteers. Circulation 1970, 42:867-873.
    • (1970) Circulation , vol.42 , pp. 867-873
    • Doherty, J.E.1    Flanigan, W.J.2    Murphy, M.L.3
  • 17
    • 0018366448 scopus 로고
    • Biotransformation and elimination of digoxin with normal and minimal renal function
    • Gault M.H., Sugden D., Maloney C., Ahmed M., Tweeddale M. Biotransformation and elimination of digoxin with normal and minimal renal function. Clin. Pharmacol. Ther. 1979, 25:499-513.
    • (1979) Clin. Pharmacol. Ther. , vol.25 , pp. 499-513
    • Gault, M.H.1    Sugden, D.2    Maloney, C.3    Ahmed, M.4    Tweeddale, M.5
  • 18
    • 0016737954 scopus 로고
    • Digoxin concentrations in postmortem specimens after overdose and therapeutic use
    • DiMaio V.J., Garriott J.C., Putnam R. Digoxin concentrations in postmortem specimens after overdose and therapeutic use. J. Forensic Sci. 1975, 20:340-347.
    • (1975) J. Forensic Sci. , vol.20 , pp. 340-347
    • DiMaio, V.J.1    Garriott, J.C.2    Putnam, R.3
  • 20
    • 0016799691 scopus 로고
    • Postmortem assay of digoxin by radioimmunoassay
    • Holt D.W., Benstead J.G. Postmortem assay of digoxin by radioimmunoassay. J. Clin. Pathol. 1975, 28:483-486.
    • (1975) J. Clin. Pathol. , vol.28 , pp. 483-486
    • Holt, D.W.1    Benstead, J.G.2
  • 21
    • 0018134776 scopus 로고
    • Correlation of antemortem and postmortem digoxin levels
    • Vorpahl T.E., Coe J.I. Correlation of antemortem and postmortem digoxin levels. J. Forensic Sci. 1978, 23:329-334.
    • (1978) J. Forensic Sci. , vol.23 , pp. 329-334
    • Vorpahl, T.E.1    Coe, J.I.2
  • 23
    • 0016593009 scopus 로고
    • Post-mortem distribution and tissue concentrations of digoxin in infants and adults
    • Andersson K.E., Bertler A., Wettrell G. Post-mortem distribution and tissue concentrations of digoxin in infants and adults. Acta Paediatr. Scand. 1975, 64:497-504.
    • (1975) Acta Paediatr. Scand. , vol.64 , pp. 497-504
    • Andersson, K.E.1    Bertler, A.2    Wettrell, G.3
  • 24
    • 0018776818 scopus 로고
    • Cardiac glycosides and metabolites-problems of recovery in tissue extracts. Separation of visible substance spots in the nanogram range
    • Aderjan R., Doster S., Petri H., Schmidt G. Cardiac glycosides and metabolites-problems of recovery in tissue extracts. Separation of visible substance spots in the nanogram range. Z. Rechtsmed. 1979, 83:201-207.
    • (1979) Z. Rechtsmed. , vol.83 , pp. 201-207
    • Aderjan, R.1    Doster, S.2    Petri, H.3    Schmidt, G.4
  • 25
    • 0018134776 scopus 로고
    • Correlation of antemortem and postmortem digoxin levels
    • Vorpahl T.E., Coe J.I. Correlation of antemortem and postmortem digoxin levels. J. Forensic Sci. 1978, 23:329-334.
    • (1978) J. Forensic Sci. , vol.23 , pp. 329-334
    • Vorpahl, T.E.1    Coe, J.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.