TRAF3 regulates homeostasis of CD8+ central memory T cells

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Yi, Zuoan ^a   Stunz, Laura L ^a   Lin, Wai Wai ^a   Bishop, Gail A ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD44V ANTIGEN; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 7; L SELECTIN; MITOGEN ACTIVATED PROTEIN KINASE; S6 KINASE; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL METABOLISM; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FLOW CYTOMETRY; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN CELL; ANIMAL; C57BL MOUSE; DEFICIENCY; FEMALE; HOMEOSTASIS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; METABOLISM;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HOMEOSTASIS; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; LYMPHOCYTE ACTIVATION; MALE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 3;

EID: 84904251040     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102120     Document Type: Article

References (35)

1. + T cell differentiation. Nat Rev Immunol 12: 749-761.
2. Mueller SN, Gebhardt T, Carbone FR, Heath WR (2013) Memory T cell subsets, migration patterns, and tissue residence. Annu Rev Immunol 31: 137-161.
3. Amsen D, Backer RA, Helbig C (2013) Decisions on the road to memory. Adv Exp Med Biol 785: 107-120.
4. Ahmed R, Gray D (1996) Immunological memory and protective immunity: understanding their relation. Science 272: 54-60. (Pubitemid 26110754)
5. Mempel TR, Henrickson SE, von Andrian UH (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427: 154-159. (Pubitemid 38094955)
6. Wherry EJ, Teichgräber V, Becker TC, Masopust D, Kaech SM, et al. (2003) Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 4: 225-234. (Pubitemid 36322131)
7. Schluns KS, Kieper WC, Jameson SC, Lefrancois L (2000) Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nature Immunol 1: 426-432.
8. Surh CD, Sprent J (2008) Homeostasis of naive and memory T cells. Immunity 29: 848-862.
9. Jameson SC, Masopust D (2009) Diversity in T cell memory: an embarrassment of riches. Immunity 31: 859-871.
10. + T-cell memory. Nat Rev Immunol 8: 107-119.
11. Häcker H, Tseng PH, Karin M (2011) Expanding TRAF function: TRAF3 as a tri-faced immune regulator. Nat Rev Immunol 11: 457-468.
12. Hildebrand JM, Yi Z, Buchta CM, Poovassery J, Stunz LL, et al. (2011) Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions. Immunol Rev 244: 55-74.
13. Yi Z, Lin WW, Stunz LL, Bishop GA (2014) Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions. Cytokine Growth Factor Rev 25: 147-156.
14. Xu Y, Cheng G, Baltimore D (1996) Targeted Disruption of TRAF3 Leads to Postnatal Lethality and Defective T-Dependent Immune Responses. Immunity 5: 407-415. (Pubitemid 26423469)
15. Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, et al. (2006) Specificity in TLR signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439: 204-207. (Pubitemid 43083141)
16. Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, et al. (2006) Critical role of TRAF3 in the TLR-dependent and independent antiviral response. Nature 439: 208-211. (Pubitemid 43083142)
17. Bishop GA, Xie P (2007) Multiple roles of TRAF3 signaling in lymphocyte function. Immunol Res 39: 22-32. (Pubitemid 47574889)
18. Xie P, Poovassery J, Stunz LL, Smith SM, Schultz ML, et al. (2011) Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes. J Leukoc Biol 90: 1149-1157.
19. Xie P, Stunz LL, Larison KD, Yang B, Bishop GA (2007) TRAF3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity 27: 253-267.
20. Gardam S, Sierro F, Basten A, Mackay F, Brink R (2008) TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity 28: 391-401.
21. Xie P, Kraus ZJ, Stunz LL, Liu Y, Bishop GA (2011) TRAF3 is required for T cell-mediated immunity and TCR/CD28 signaling. J Immunol 186: 143-155.
22. Zhu S, Pan W, Shi P, Gao H, Zhao F, et al. (2010) Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling. J Exp Med 207: 2647-2662.
23. Yi Z, Stunz LL, Bishop GA (2013) TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells. J Exp Med 210: 1079-1086.
24. Chang JH, Hu H, Jin J, Puebla-Osorio N, Xiao Y, et al. (2014) TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. J Exp Med 211: 137-151.
25. Bishop GA (2013) The many faces of TRAF molecules in immune regulation. J Immunol 191: 3483-3485.
26. Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, et al. (2008) Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol 9: 1364-1370.
27. Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, et al. (2008) Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol 9: 1371-1378.
28. Hofmann J, Mair F, Greter M, Schmidt-Supprian M, Becher B (2011) NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. J Exp Med 208: 1917-1929.
29. + regulatory T cells in mice. PLoS One 8: e76216.
30. Boehm T, Scheu S, Pfeffer K, Bleul CC (2003) Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J Exp Med 198: 757-769. (Pubitemid 37087775)
31. Zhu M, Chin RK, Christiansen PA, Lo JC, Liu X, et al. (2006) NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway. J Clin Invest 116: 2964-2971. (Pubitemid 44684481)
32. Miyawaki S, Nakamura Y, Suzuka H, Koba M, Yasumizu R, et al. (1994) A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur J Immunol 24: 429-434. (Pubitemid 24041135)
33. Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, et al. (2008) The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 29: 423-437.
34. Kajiura F, Sun S, Nomura T, Izumi K, Ueno T, et al. (2004) NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. J Immunol 172: 2067-2075. (Pubitemid 38182352)
35. Rowe AM, Murray SE, Raué HP, Koguchi Y, Slifka MK, et al. (2013) A cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory. J Immunol 191: 3663-3672.