In vitro biocompatibility and antibacterial efficacy of a degradable poly(l-lactide-co-epsilon-caprolactone) copolymer incorporated with silver nanoparticles

Annals of Biomedical Engineering

Volumn 42, Issue 7, 2014, Pages 1482-1493

  Samberg, Meghan E ^a,b   Mente, Peter ^b   He, Ting ^a   King, Martin W ^a   Monteiro Riviere, Nancy A ^a,b,c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b Biomedical Research Imaging Center   (United States)

^c KANSAS STATE UNIVERSITY   (United States)

Author keywords

Biocompatibility; Keratinocyte; Nanoparticle; Scaffold; Skin tissue engineering

Indexed keywords

BIOCOMPATIBILITY; CELL CULTURE; NANOPARTICLES; SCAFFOLDS; SCAFFOLDS (BIOLOGY); SCANNING ELECTRON MICROSCOPY; TENSILE TESTING; TISSUE;

ANTIBACTERIAL EFFICACY; ANTIBACTERIAL PROPERTIES; HUMAN EPIDERMAL KERATINOCYTES; KERATINOCYTES; SILVER NANOPARTICLES; SILVER NANOPARTICLES (AGNPS); SKIN TISSUE ENGINEERING; UNIAXIAL TENSILE TEST;

SILVER;

BIOCIDE; COPOLYMER; POLY(LACTIDE CO EPSILON CAPROLACTONE); SILVER NANOPARTICLE; TISSUE SCAFFOLD; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BIODEGRADABLE PLASTIC; LACTIDE-CAPROLACTONE COPOLYMER; METAL NANOPARTICLE; POLYESTER; SILVER;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOCOMPATIBILITY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DEGRADATION; ELECTROSPINNING; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EPIDERMIS; MATERIALS TESTING; METABOLISM;

ANTI-BACTERIAL AGENTS; BIODEGRADABLE PLASTICS; CELL PROLIFERATION; EPIDERMIS; HUMANS; KERATINOCYTES; MATERIALS TESTING; METAL NANOPARTICLES; POLYESTERS; SILVER; TISSUE ENGINEERING;

EID: 84904246786     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0929-9     Document Type: Article

References (30)

1. Alt, V., T. Bechert, P. Steinrücke, M. Wagener, P. Seidel, E. Dingeldein, E. Domann, and R. Schnettler. An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. Biomaterials 18:4383-4391, 2004.
2. Boyce, S. T., R. J. Kagan, D. G. Greenhalgh, P. Warner, K. P. Yakuboff, T. Palmieri, and G. D. Warden. Cultured skin substitutes reduce requirements for harvesting of skin autograft for closure of excised, full-thickness burn. J. Trauma. 60(4):821-829, 2006.
3. Burd, A., and T. Chiu. Allogenic skin in the treatment of burns. Clin. Dermatol. 23:376-387, 2005.
4. Chen, W., Y. Liu, H. S. Courtney, M. Bettenga, C. M. Agrawal, D. Bumgardner, and J. L. Ong. In vitro anti-bacterial and biological properties of magnetron co-sputtered silver-containing hydroxyapatite coating. Biomaterials 27:5512-5517, 2006.
5. Chung, S., N. P. Ingle, G. A. Montero, S. H. Kim, and M. W. King. Bioresorbable elastomeric vascular tissue engineering scaffolds via melt spinning and electrospinning. Acta Biomater. 6(6):1958-1967, 2010.
6. De Groot, J. H., F. M. Zijlstra, H. W. Kuipers, A. J. Pennings, J. Klompmaker, R. P. H. Veth, and H. W. Jansen. Meniscal tissue regeneration in porous 50/50 copoly(l-lactide/ε-caprolactone) implants. Biomaterials 18(8):613-622, 1997.
7. Den Dunnen, W. F., B. van der Lei, P. H. Robinson, A. Holwerda, A. J. Pennings, and J. M. Schakenraad. Biological performance of a degradable poly(lactic acid-ε-caprolactone) nerve guide influence of tube dimensions. J. Biomed. Mater. Res. 29(6):757-766, 1995.
8. Furno, F., K. S. Morley, B. Wong, B. L. Sharp, P. L. Arnold, S. M. Howdle, R. Bayston, P. D. Brown, P. D. Winship, and H. J. Reid. Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection? J. Antimicrob. Chemother. 54:1019-1024, 2004.
9. Garfein, E. Skin replacement products and markets. In: Biomaterials for Treating Skin Loss. Boca Raton, FL: CRC Press, 2009, pp. 9-17.
10. Hiljanen-Vainio, M., T. Karjalainen, and J. Seppala. Biodegradable lactone copolymers. 1. Characterization and mechanical behavior of ε-caprolactone and lactide copolymers. J. Appl. Polym. Sci. 59(8):1281-1288, 1996.
11. Hong, K. H., J. L. Y. Park, I. H. Sul, J. H. Youk, and T. J. Kang. Preparation of antimicrobial poly(vinyl alcohol) nanofibers containing silver nanoparticles. J. Polym. Sci. Part B 44(17):2468-2474, 2006.
12. Inoguchi, H., I. K. Kwon, E. Inoue, K. Takamizawa, Y. Maehara, and T. Matsuda. Mechanical responses of a compliant electrospun poly(l-lactide-co- epsilon-caprolactone) small-diameter vascular graft. Biomaterials 27:1470-1478, 2006.
13. Jeon, H. J., J. S. Kim, T. G. Kim, J. H. Kim, W.-R. Yu, and J. H. Youk. Preparation of poly(ε-caprolactone)-based polyurethane nanofibers containing silver nanoparticles. Appl. Surf. Sci. 254(18):5886-5890, 2008.
14. Jeong, S. I., S. H. Kim, Y. H. Kim, Y. Jung, J. H. Kwon, B. S. Kim, and Y. M Lee. Manufacture of elastic biodegradable PLCL scaffolds for mechano-active vascular tissue-engineering. J. Biomater. Sci. Polym. Ed. 15(5):645-660, 2004.
15. Kim, B.-S., and D. J. Mooney. Scaffold for engineering smooth muscle under cyclic mechanical strain conditions. J. Biomech. Eng. 122:210-215, 2000.
16. Kwon, K., S. Kidoaki, and T. Matsuda. Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential. Biomaterials 26(18):3929-3939, 2005.
17. Langer, R., and J. P. Vacanti. Tissue engineering. Science 260(5110):920-928, 1993.
18. Liu, X., T. Lin, J. Fang, G. Yao, H. Zhao, M. Dodson, and X. Wang. In vivo wound healing and antibacterial performances of electrospun nanofiber membranes. J. Biomed. Mater. Res. A 94(2):499-508, 2010.
19. Liu, W., Y. Wu, C. Wang, H. C. Li, T. Wang, C. Y. Liao, L. Cui, Q. F. Zhou, B. Yan, and G. B. Jiang. Impact of silver nanoparticles on human cells: effect of particle size. Nanotoxicol. 4(3):319-330, 2010.
20. McCullen, S. D., D. R. Stevens, W. A. Roberts, L. I. Clarke, S. H. Bernacki, R. E. Gorga, and E. G. Loboa. Characterization of electrospun nanocomposite scaffolds and biocompatibility with adipose-derived human mesenchymal stem cells. Int. J. Nanomedicine 2(2):253-263, 2007.
21. Mo, X. M., C. Y. Xu, M. Kotaki, and S. Ramakrishna. Electrospun P(LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation. Biomaterials 25(10):1883-1890, 2004.
22. Monteiro-Riviere, N. A., A. O. Inman, and L. W. Zhang. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Tox. Appl. Pharma. 234:222-235, 2009.
23. Monteiro-Riviere, N. A. Structure and function of skin. In: Toxicology of the Skin-Target Organ Series, edited by N. A. Monteiro-Riviere. New York: Informa Healthcare, 2010, Vol. 29, pp. 1-18.
24. Park, E.-J., J. Yi, Y. Kim, K. Choi, and K. Parl. Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicol. In Vitro 24(3):872-878, 2010.
25. Pham, Q. P., U. Sharma, and A. G. Mikos. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng. 12(5):1197-1211, 2006.
26. Samberg, M. E., S. J. Oldenburg, and N. A. Monteiro-Riviere. Evaluation of silver nanoparticle toxicity in skin in vivo and keratinocytes in vitro. Environ. Health Perspect. 118(3):407-413, 2010.
27. Samberg, M. E., P. E. Orndorff, and N. A. Monteiro-Riviere. Antibacterial efficacy of silver nanoparticles of different sizes, surface conditions and synthesis methods. Nanotoxicology 5(2):244-253, 2011.
28. Shahverdi, A. R., A. Fakhimi, H. R. H. R. Shahverdi, and S. Minaian. Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomedicine 3(2):168-171, 2007.
29. Wikler, M. A., F. R. Cockerill III, K. Bush, M. N. Dudley, G. E. Eliopoulos, D. J. Hardy, et al. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. In: Approved Standard-8th Edition, Clinical and Laboratory Standards Institute Document M07-A8. Wayne, PA, 2009, 29(2).
30. Zhong, S. P., Y. Z. Zhang, and C. T. Lim. Tissue scaffolds for skin wound healing and dermal reconstruction. WIREs Nanomed. Nanobiotechnol. 2:510-525, 2010.