Evaluation of bias, precision, robustness and runtime for estimation methods in NONMEM 7

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 41, Issue 3, 2014, Pages 223-238

  Johansson, Åsa M ^a   Ueckert, Sebastian ^a   Plan, Elodie L ^a   Hooker, Andrew C ^a   Karlsson, Mats O ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Estimation algorithms; FOCE; Importance sampling; Laplace; Non linear mixed effect models; SAEM

Indexed keywords

ACCURACY; ALGORITHM; ARTICLE; COMPUTER PROGRAM; EVALUATION STUDY; MONTE CARLO METHOD; POWER ANALYSIS; PRIORITY JOURNAL; PROBABILITY; SAMPLING BIAS; SIMULATION; STOCHASTIC MODEL; HUMAN; METABOLISM; PHARMACOKINETICS; REPRODUCIBILITY; STANDARDS; STATISTICAL BIAS; STATISTICAL MODEL;

ADRENERGIC RECEPTOR BLOCKING AGENT; IMIDAZOLE DERIVATIVE; MOXONIDINE; NORADRENALIN;

ALGORITHMS; BIAS (EPIDEMIOLOGY); HUMANS; IMIDAZOLES; MODELS, STATISTICAL; NOREPINEPHRINE; PHARMACOKINETICS; REPRODUCIBILITY OF RESULTS; SOFTWARE; SYMPATHOLYTICS;

EID: 84904207580     PISSN: 1567567X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/s10928-014-9359-z     Document Type: Article

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