Site-specific labeling of proteins and peptides with trans-cyclooctene containing handles capable of tetrazine ligation

Chemical Biology and Drug Design

Volumn 84, Issue 2, 2014, Pages 140-147

  Wollack, James W ^a   Monson, Benjamin J ^b   Dozier, Jonathan K ^c   Dalluge, Joseph J ^c   Poss, Kristina ^a   Hilderbrand, Scott A ^d   Distefano, Mark D ^c  

^a ST CATHERINE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Minnesota   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

bioorthogonal; inverse electron demand Diels Alder; protein farnesyltransferase; protein prenylation; tetrazine ligation; trans cyclooctene

Indexed keywords

COPPER; CYCLOOCTENE GERANYL DIPHOSPHATE; DANSYL CHLORIDE; GERANIOL; PEPTIDE; PHOSPHATE; PROTEIN; PROTEIN FARNESYLTRANSFERASE; UNCLASSIFIED DRUG; CYCLOOCTANE DERIVATIVE; DITERPENE; GERANYL DIPHOSPHATE; P21(RAS) FARNESYL-PROTEIN TRANSFERASE; PYROPHOSPHORIC ACID DERIVATIVE; RECOMBINANT PROTEIN; TRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYST; CYCLOADDITION; CYTOTOXICITY; ENZYME MODIFICATION; PRENYLATION; PRIORITY JOURNAL; SOLUBILITY; SYNTHESIS; CHEMISTRY; ENZYME SPECIFICITY; METABOLISM; PROTEIN PRENYLATION;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; CYCLOOCTANES; DIPHOSPHATES; DITERPENES; PEPTIDES; PROTEIN PRENYLATION; PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84904116942     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12303     Document Type: Article

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