Enhanced slow inactivation of the human skeletal muscle sodium channel causing normokalemic periodic paralysis

Cellular and Molecular Neurobiology

Volumn 34, Issue 5, 2014, Pages 707-714

  Wu, Lei ^a   Zhang, Baorong ^a   Kang, Ying ^b   Wu, Weiping ^c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Analytic Center Zhejiang Environmental Monitoring Center   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

NormoPP; Prolonged recovery; R675Q; SCN4A; Slow inactivation

Indexed keywords

SODIUM CHANNEL NAV1.4; SCN4A PROTEIN, HUMAN; SODIUM CHANNEL BLOCKING AGENT;

ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; HYPERPOLARIZATION; MEMBRANE CURRENT; MUSCLE FIBER MEMBRANE POTENTIAL; NORMOKALEMIC PERIODIC PARALYSIS; PATCH CLAMP TECHNIQUE; PERIODIC PARALYSIS; PRIORITY JOURNAL; REPOLARIZATION; SKELETAL MUSCLE; SODIUM CHANNEL ENHANCED SLOW INACTIVATION; SODIUM CONDUCTANCE; SODIUM CURRENT; SODIUM TRANSPORT; STEADY STATE; WILD TYPE; ACTION POTENTIAL; ASIAN CONTINENTAL ANCESTRY GROUP; CHANNEL GATING; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; MEMBRANE POTENTIAL; MUTATION; PHYSIOLOGY;

ACTION POTENTIALS; ASIAN CONTINENTAL ANCESTRY GROUP; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; MUTATION; NAV1.4 VOLTAGE-GATED SODIUM CHANNEL; PARALYSES, FAMILIAL PERIODIC; SODIUM CHANNEL BLOCKERS;

EID: 84904112773     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-014-0052-y     Document Type: Article

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