Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents

Cellular and Molecular Neurobiology

Volumn 34, Issue 5, 2014, Pages 643-649

  Chowdhury, Subir Roy ^a   Saleh, Ali ^a   Akude, Eli ^a   Smith, Darrell R ^a   Morrow, Dwane ^a   Tessler, Lori ^a   Calcutt, Nigel A ^b   Fernyhough, Paul ^a,c  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Bioenergetics profile; CNTF; Diabetic sensory neuropathy; Dorsal root ganglia; Mitochondrial membrane potential

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; OLIGOMYCIN; STAT PROTEIN; STAT3 PROTEIN; STREPTOZOCIN; TYROSINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CONTROLLED STUDY; GENE EXPRESSION; HYPERPOLARIZATION; MALE; MITOCHONDRIAL BIOENERGETICS; MITOCHONDRIAL RESPIRATION; NERVE CELL CULTURE; NERVE FIBER GROWTH; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REDUCTION; RESPIRATION CONTROL; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; C57BL MOUSE; CELL CULTURE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ENERGY METABOLISM; METABOLISM; MITOCHONDRION; MOUSE; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

MUS; RATTUS; RODENTIA;

ANIMALS; CELLS, CULTURED; CILIARY NEUROTROPHIC FACTOR; DIABETES MELLITUS, EXPERIMENTAL; ENERGY METABOLISM; JANUS KINASES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84904103699     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-014-0054-9     Document Type: Article

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