Bacteremic pneumococcal pneumonia in elderly and very elderly patients

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 69, Issue 8, 2014, Pages 1018-1024

  Ruiz, Luis A ^a   Zalacain, Rafael ^a   Capelastegui, Alberto ^b   Bilbao, Amaia ^c   Gomez, Ainhoa ^a   Uranga, Ane ^b   España, Pedro P ^b  

^a HOSPITAL DE CRUCES   (Spain)

^b HOSPITAL DE GALDAKAO   (Spain)

^c HOSPITAL DE BASURTO   (Spain)

Author keywords

Bacteremic pneumococcal pneumonia; Pneumonia and mortality; Pneumonia in elderly persons

Indexed keywords

AGE; AGED; ARTICLE; BACTEREMIC PNEUMOCOCCAL PNEUMONIA; FEMALE; HOST PATHOGEN INTERACTION; HUMAN; MALE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PNEUMONIA AND MORTALITY.; PNEUMONIA IN ELDERLY PERSONS; PROGNATHIA; PROGNOSIS; RISK FACTOR; STREPTOCOCCUS PNEUMONIA; TREATMENT OUTCOME; VERY ELDERLY;

BACTEREMIC PNEUMOCOCCAL PNEUMONIA; PNEUMONIA AND MORTALITY.; PNEUMONIA IN ELDERLY PERSONS;

AGE FACTORS; AGED; AGED, 80 AND OVER; FEMALE; HOSPITAL MORTALITY; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MULTIVARIATE ANALYSIS; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); PNEUMONIA, PNEUMOCOCCAL; PROGNATHISM; PROGNOSIS; RISK FACTORS;

EID: 84904015745     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt288     Document Type: Article

References (30)

1. Callahan CM, Wolinsky FD. Hospitalization for pneumonia among older adults. J Gerontol A Biol Sci Med Sci. 1996;51:M276-M282.
2. Musher DM, Alexandraki I, Graviss EA, et al. Bacteremic and nonbacteremic pneumococcal pneumonia. A prospective study. Medicine (Baltimore). 2000;79:210-221.
3. Brandenburg JA, Marrie TJ, Coley CM, et al. Clinical presentation, processes and outcomes of care for patients with pneumococcal pneumonia. J Gen Intern Med. 2000;15:638-646.
4. Bordon J, Peyrani P, Brock GN, et al.; CAPO Study Group. The presence of pneumococcal bacteremia does not influence clinical outcomes in patients with community-acquired pneumonia: results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort study. Chest. 2008;133:618-624.
5. Gutierrez F, Masia M, Mirete C, et al. The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens. J Infect. 2006;53:166-174.
6. Ruhnke GW, Coca-Perraillon M, Kitch BT, Cutler DM. Marked reduction in 30-day mortality among elderly patients with community-acquired pneumonia. Am J Med. 2011;124:171-178.
7. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify lowrisk patients with community-acquired pneumonia. N Engl J Med. 1997;336:243-250.
8. Weinberger DM, Harboe ZB, Sanders EA, et al. Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis. 2010;51:692-699.
9. Menendez R, Torres A, Aspa J, Capelastegui A, Prat C, Rodriguez de Castro F; Sociedad Espanola de Neumologia y Cirugia Toracica. Community acquired pneumonia. New guidelines of the Spanish Society of Chest Diseases and Thoracic Surgery (SEPAR). Arch Bronconeumol. 2010;46:543-558.
10. Levy MM, Fink MP, Marshall JC, et al.; SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003;31:1250-1256.
11. Menendez R, Torres A, Zalacain R, et al.; Neumofail Group. Risk factors of treatment failure in community acquired pneumonia: implications for disease outcome. Thorax. 2004;59:960-965.
12. Boumendil A, Angus DC, Guitonneau AL, et al.; ICE-CUB study group. Variability of intensive care admission decisions for the very elderly. PLoS One. 2012;7:e34387.
13. Wunsch H, Guerra C, Barnato AE, Angus DC, Li G, Linde-Zwirble WT. Three-year outcomes for Medicare beneficiaries who survive intensive care. JAMA. 2010;303:849-856.
14. Lynch JP 3rd, Zhanel GG. Streptococcus pneumoniae: epidemiology and risk factors, evolution of antimicrobial resistance, and impact of vaccines. Curr Opin Pulm Med. 2010;16:217-225.
15. Garnacho-Montero J, Garcia-Cabrera E, Diaz-Martin A, et al. Determinants of outcome in patients with bacteraemic pneumococcal pneumonia: importance of early adequate treatment. Scand J Infect Dis. 2010;42:185-192.
16. Lujan M, Gallego M, Fontanals D, Mariscal D, Rello J. Prospective observational study of bacteremic pneumococcal pneumonia: effect of discordant therapy on mortality. Crit Care Med. 2004;32:625-631.
17. File TM Jr, Mandell LA. What is optimal antimicrobial therapy for bacteremic pneumococcal pneumonia? Clin Infect Dis. 2003;36:396-398.
18. Conte HA, Chen YT, Mehal W, Scinto JD, Quagliarello VJ. A prognostic rule for elderly patients admitted with community-acquired pneumonia. Am J Med. 1999;106:20-28.
19. Myint PK, Kamath AV, Vowler S, Maisey DN, Harrison BD. Severity assessment criteria recommended by the British Thoracic Society (BTS) for community-acquired pneumonia and older patients. Should SOAR (systolic blood pressure, oxygenation, age and respiratory rate criteria be used in older people? A compilation study of two prospective cohorts. Age Ageing. 2006;35:286-291.
20. Naupane B, Walet S, Krueger P, Marrie T, Loeb M. Predictors of inhospital mortality and re-hospitalization in older adults with community-acquired pneumonia: a prospective cohort study. BMC Geriatr. 2010;10:22.
21. Pilotto A, Addante F, Ferrucci L, et al. The multidimensional prognostic index predicts short-and long-term mortality in hospitalized geriatric patients with pneumonia. J Gerontol A Biol Sci Med Sci. 2009;64:880-887.
22. Torres OH, Munoz J, Ruiz D, et al. Outcome predictors of pneumonia in elderly patients: importance of functional assessment. J Am Geriatr Soc. 2004;52:1603-1609.
23. Naito T, Suda T, Yasuda K, et al. A validation and potential modification of the Pneumonia Severity Index in elderly patients with community-acquired pneumonia. J Am Geriatr Soc. 2006;54:1212-1219.
24. Garcia-Ordonez MA, Garcia-Jimenez JM, Paez F, et al. Clinical aspects and prognostic factors in elderly patients hospitalised for community-acquired pneumonia. Eur J Clin Microbiol Infect Dis. 2001;20:14-19.
25. Zalacain R, Torres A, Celis R, et al.; Pneumonia in the elderly working group, Area de Tuberculosis e Infecciones Respiratorias. Communityacquired pneumonia in the elderly: Spanish multicentre study. Eur Respir J. 2003;21:294-302.
26. Chi RC, Jackson LA, Neuzil KM. Characteristics and outcomes of older adults with community-acquired pneumococcal bacteremia. J Am Geriatr Soc. 2006;54:115-120.
27. Marrie TJ, Tyrrell GJ, Garg S, Vanderkooi OG. Factors predicting mortality in invasive pneumococcal disease in adults in Alberta. Medicine (Baltimore). 2011;90:171-179.
28. Naucler P, Darenberg J, Morfeldt E, Ortqvist A, Henriques Normark B. Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia. Thorax. 2013;68:571-579.
29. Lim WS, van der Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax. 2003;58:377-382.
30. Garau J, Aguilar L, Rodriguez-Creixems M, et al. Influence of comorbidity and severity on the clinical outcome of bacteremic pneumococcal pneumonia treated with beta-lactam monotherapy. J Chemother. 1999;11:266-272