Diagnostic and resistance testing for Mycoplasma genitalium: What will it take?

Clinical Infectious Diseases

Volumn 59, Issue 1, 2014, Pages 31-33

  Manhart, Lisa E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

diagnostic tests; drug resistance; M. genitalium

Indexed keywords

AZITHROMYCIN; DOXYCYCLINE; ANTIINFECTIVE AGENT; MACROLIDE;

ANTIBIOTIC RESISTANCE; CHLAMYDIA TRACHOMATIS; DENMARK; DIAGNOSTIC TEST; FOOD AND DRUG ADMINISTRATION; GYNECOLOGIC DISEASE; HIGH RISK PATIENT; HUMAN; MORBIDITY; MYCOPLASMA GENITALIUM; NEISSERIA GONORRHOEAE; NONSPECIFIC URETHRITIS; NOTE; PELVIC INFLAMMATORY DISEASE; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; SELF EVALUATION; SEXUALLY TRANSMITTED DISEASE; TREATMENT FAILURE; UNITED KINGDOM; UNITED STATES; URETHRITIS; DRUG EFFECTS; FEMALE; MALE; MICROBIOLOGY; MYCOPLASMOSIS;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; FEMALE; HUMANS; MACROLIDES; MALE; MYCOPLASMA GENITALIUM; MYCOPLASMA INFECTIONS;

EID: 84904002590     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu224     Document Type: Note

References (11)

1. Schwebke JR, Rompalo A, Taylor S, et al. Reevaluating the treatment of nongonococcal urethritis: emphasizing emerging pathogens-a randomized clinical trial. Clin Infect Dis 2011; 52:163-70.
2. Manhart LE, Gillespie CW, Lowens MS, et al. Standard treatment regimens for nongonococcal urethritis have similar but declining cure rates: a randomized controlled trial. Clin Infect Dis 2013; 56:934-42.
3. Salado-Rasmussen K, Jensen JS. Mycoplasma genitalium testing pattern and macrolide resistance: a Danish nationwide retrospective survey. Clin Infect Dis 2014; 59: 24-30.
4. Handsfield HH, McCutchan JA, Corey L, Ronald AR. Evaluation of new anti-infective drugs for the treatment of uncomplicated gonorrhea in adults and adolescents. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis 1992; 15(suppl 1):S123-30.
5. Manhart LE. Mycoplasma genitalium: an emergent sexually transmitted disease? Infect Dis Clin North Am 2013; 27:779-92.
6. Division of STD Prevention, Centers for Disease Control and Prevention. Sexually transmitted disease surveillance, 2000. Atlanta, GA: Department of Health and Human Services, 2001.
7. Sena AC, Lensing S, Rompalo A, et al. Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis infections in men with nongonococcal urethritis: predictors and persistence after therapy. J Infect Dis 2012; 206:357-65.
8. Pond MJ, Nori AV, Witney AA, Lopeman RC, Butcher PD, Sadiq ST. High prevalence of antibiotic-resistant Mycoplasma genitalium in nongonococcal urethritis: the need for routine testing and the inadequacy of current treatment options. Clin Infect Dis 2014; 58:631-7.
9. Totten PA, Jensen NL, Khosropour CM, et al. Azithromycin and doxycycline resistance profiles of Mycoplasma genitalium and association with treatment outcomes. Sex Transm Infect 2013; 89(suppl 1):A62.
10. US Preventive Services Task Force. Grade definitions for US Preventive Services Task Force Recommendations. Available at: http://www. uspreventiveservicestaskforce.org/uspstf/grades.htm. Accessed 19 March 2014.
11. Twin J, Jensen JS, Bradshaw CS, et al. Transmission and selection of macrolide resistant Mycoplasma genitalium infections detected by rapid high resolution melt analysis. PLoS One 2012; 7:e35593.