Cervical IL-6 and pIGFBP-1 and the prediction of neonatal outcome in symptomatic preterm labour

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 27, Issue 12, 2014, Pages 1241-1247

  Brik, Maia ^a,b   Aguar, Marta ^a   Valiente, Ana ^a   Perales, Alfredo ^a  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b Servicio de Cardiología Hospital de Torrejón de Ardoz   (Spain)

Author keywords

Cervical markers; Neonatal morbidity; Prediction; Preterm birth

Indexed keywords

INTERLEUKIN 6; PHOSPHORYLATED INSULIN GROWTH BINDING PROTEIN 1; SOMATOMEDIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; IGFBP1 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN 1;

ACCURACY; APGAR SCORE; ARTICLE; BIRTH WEIGHT; CHORIOAMNIONITIS; CONTROLLED STUDY; FEMALE; FETUS OUTCOME; GESTATIONAL AGE; HUMAN; LEUKOCYTOSIS; NEWBORN; NEWBORN INTENSIVE CARE; NEWBORN MORTALITY; OBSERVATIONAL STUDY; PREDICTIVE VALUE; PREMATURE LABOR; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; RESPIRATORY TRACT DISEASE; SENSITIVITY AND SPECIFICITY; ADULT; CHEMISTRY; INFANT, NEWBORN, DISEASES; METABOLISM; OBSTETRIC LABOR, PREMATURE; PHOSPHORYLATION; PREGNANCY; PREGNANCY OUTCOME; PROGNOSIS; UTERINE CERVIX; YOUNG ADULT;

ADULT; BIOLOGICAL MARKERS; CERVIX UTERI; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INTERLEUKIN-6; OBSTETRIC LABOR, PREMATURE; PHOSPHORYLATION; PREGNANCY; PREGNANCY OUTCOME; PROGNOSIS; YOUNG ADULT;

EID: 84904000533     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2013.854326     Document Type: Article

References (21)

1. American College of Obstetricians and Gynecologists. Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin no. 80: premature rupture of membranes; clinical management guidelines for obstetrician and gynecologists. Obstet Gynecol 2007;109:1007-19.
2. Romero R, Quintero R, Oyarzun E, et al. Intraamniotic infection and the onset of labor in preterm premature rupture of membranes. Am J Obstet Gynecol 1988;159:661-6.
3. Lee J, Romero R, Meanu Y, et al. The intensity of the fetal inflammatory response in intraamniotic inflammation with and without microbial invasion of the amniotic cavity. Am J Obstet Gynecol 2007;197:294.e1-6.
4. Ghezzi F, Gomez R, Romero R, et al. Elevated interleukin-8 concentrations in amniotic fluid of mothers whose neonates subsequently develop bronchopulmonary dysplasia. Eur J Obstet Gynecol Reprod Biol 1998;78:5-10.
5. Yoon BH, Jun JK, Romero R, et al. Amniotic fluid inflammatory cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta), neonatal brain white matter lesions, and cerebral palsy. Am J Obstet Gynecol 1997;177:19-26.
6. Berger A, Witt A, Haiden N, et al. Intrauterine infection with Ureaplasma species is associated with adverse neuromotor outcome at 1 and 2 years adjusted age in preterm infants. J Perinat Med 2009;37:72-8.
7. Romero R, Erez O, Espinoza J. Intrauterine infection, preterm labor, and cytokines. J Soc Gynecol Investig 2005;12: 463-5.
8. Hirano T, Taga T, Nakano N, et al. Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2). Proc Natl Acad Sci U S A 1985;82:5490-4.
9. Mitchell MD, Romero RJ, Edwin SS, Trautman MS. Prostaglandins and parturition. Reprod Fertil Dev 1995;7:623-32.
10. Cobo T, Palacio M, Mart?́nez-Terrón M, et al. Clinical and inflammatory markers in amniotic fluid as predictors of adverse outcomes in preterm premature rupture of membranes. Am J Obstet Gynecol 2011;205:126 e1-8.
11. Brik M, Antonio P, Perales-Puchalt A, et al. Cervical interleukin-6 as a predictive test for preterm delivery in symptomatic women: preliminary results. Eur J Obstet Gynecol Reprod Biol 2011;155: 14-18.
12. Ng PC, Lams HS. Diagnostic markers for neonatal sepsis. Curr Opin Pediatr 2006;18:125-31.
13. Kayem G, Goffinet F, Batteux F. Detection of interleukin-6 in vaginal secretions of women with preterm premature rupture of membranes and its association with neonatal infection: a rapid immunochromatographic test. Am J Obstet Gynecol 2005;192: 140-5.
14. Goffinet F, Kayem G, Maillard F, et al. Detection of interleukin 6 mRNA by RT-PCR in vaginal secretions: association with preterm delivery and neonatal infection in women with preterm labour and intact membranes. Eur J OBstet Gynecol Reprod Biol 2005;123: 167-73.
15. Kurkinen-Raty M, Ruokonen A, Vuopala S, et al. Combination of cervical interleukin-6 and -8, phosphorylated insulin-like growth factor binding protein-1 in and transvaginal cervical ultrasonography in assessment of the risk of preterm birth. BJOG 2001;108: 875-81.
16. Vousden N, Chandiramani M, Seed P, Shennan A. Interleukin-6 bedside testing in women at high risk of preterm birth. J Matern Fetal Neonatal Med 2011;4:1301-4.
17. Skrablin S, Lovric H, Banovic V, et al. Maternal plasma interleukin-6, interleukin-1beta and C-reactive protein as indicators of tocolysis failure and neonatal outcome after preterm delivery. J Matern Fetal Neonatal Med 2007;20:335-41.
18. Hassanein SM, El-Farrash RA, Hafez HM, et al. Cord blood interleukin-6 and neonatal morbidities among preterm infants with PCR-positive Ureaplasma urealyticum. J Matern Fetal Neonatal Med 2012;25:2106-10.
19. Cernada M, Bad?́a N, Modesto V, et al. Cord blood interleukin-6 as a predictor of early-onset neonatal sepsis. Acta Paediatr 2012;101: e203-7.
20. Gomez R, Romero R, Medina L, et al. Cervicovaginal fibronectin improves the prediction of preterm delivery based on sonographic cervical length in patients with preterm uterine contractions and intact membranes. Am J Obstet Gynecol 2005; 192:350-9.
21. Brik M, Hernández AI, Pedraz CC, Perales A. Phosphorylated insulin-like growth factor binding protein-1 and cervical measurement in women with threatening preterm birth. Acta Obstet Gynecol Scand 2010;89:268-74.