Short telomeres: A repeat offender in IPF

The Lancet Respiratory Medicine

Volumn 2, Issue 7, 2014, Pages 513-514

  Stanley, Susan E ^a   Armanios, Mary ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE; DNA;

AMINO ACID SEQUENCE; CELL DIVISION; CHROMOSOME DISORDER; CHROMOSOME SIZE; COHORT ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; FAMILIAL DISEASE; FIBROSING ALVEOLITIS; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC RISK; HETEROZYGOTE; HUMAN; INTERSTITIAL LUNG DISEASE; NOTE; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SURVIVAL TIME; TANDEM REPEAT; TELOMERE SHORTENING; FEMALE; GENETICS; MALE; MORTALITY;

DNA; FEMALE; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; TELOMERE SHORTENING;

EID: 84903995899     PISSN: 22132600     EISSN: 22132619     Source Type: Journal    
DOI: 10.1016/S2213-2600(14)70140-7     Document Type: Note

References (11)

1. Stuart BD, Lee JS, Kozlitina J, et al. Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Lancet Respir Med 2014, published online June 17. http://dx.doi.org/10.1016/S2213-2600(14)70124-9.
2. Armanios M Telomerase and idiopathic pulmonary fibrosis. Mutat Res 2012, 730:52-58.
3. Armanios MY, Chen JJ, Cogan JD, et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N Engl J Med 2007, 356:1317-1326.
4. Parry EM, Alder JK, Qi X, Chen JJ, Armanios M Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase. Blood 2011, 117:5607-5611.
5. Jonassaint NL, Guo N, Califano JA, Montgomery EA, Armanios M The gastrointestinal manifestations of telomere-mediated disease. Aging Cell 2013, 12:319-323.
6. Silhan LL, Shah PD, Chambers DC, et al. Lung transplantation in telomerase mutation carriers with pulmonary fibrosis. Eur Respir J 2014, published online May 15. 10.1183/09031936.00060014.
7. Alder JK, Chen JJ, Lancaster L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci USA 2008, 105:13051-13056.
8. Cronkhite JT, Xing C, Raghu G, et al. Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med 2008, 178:729-737.
9. King TE, Pardo A, Selman M Idiopathic pulmonary fibrosis. Lancet 2011, 378:1949-1961.
10. Aubert G, Hills M, Lansdorp PM Telomere length measurement-caveats and a critical assessment of the available technologies and tools. Mutat Res 2012, 730:59-67.
11. Armanios M Telomeres and age-related disease: how telomere biology informs clinical paradigms. J Clin Invest 2013, 123:996-1002.