Plasticity of hippocampal subfield volume cornu ammonis 2+3 over the course of withdrawal in patients with alcohol dependence

JAMA Psychiatry

Volumn 71, Issue 7, 2014, Pages 806-811

  Kühn, Simone ^a   Charlet, Katrin ^b   Schubert, Florian ^c   Kiefer, Falk ^d   Zimmermann, Peter ^e   Heinz, Andreas ^b   Gallinat, Jürgen ^b,f  

^a MAX PLANCK INSTITUTE FOR HUMAN DEVELOPMENT   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^d CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^e Psychotrauma Center of the German Military Bundeswehrkrankenhaus   (Germany)

^f UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL ABSTINENCE; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DENTATE HILUS; DISEASE SEVERITY; DRINKING BEHAVIOR; FEMALE; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HUMAN; LONGITUDINAL STUDY; MALE; NERVE CELL PLASTICITY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; SEX RATIO; SUBICULUM; HIPPOCAMPUS; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY; SEVERITY OF ILLNESS INDEX; WITHDRAWAL SYNDROME;

ADULT; ALCOHOL ABSTINENCE; ALCOHOLISM; CA2 REGION, HIPPOCAMPAL; CA3 REGION, HIPPOCAMPAL; FEMALE; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURONAL PLASTICITY; SEVERITY OF ILLNESS INDEX; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84903956918     PISSN: 2168622X     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapsychiatry.2014.352     Document Type: Article

References (54)

1. Ming G-L, Song H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron. 2011;70(4):687-702.
2. Lövdén M,Wenger E, Martensson J, Lindenberger U, Bäckman L. Structural brain plasticity in adult learning and development. Neurosci Biobehav Rev. 2013;37(9):2296-2310.
3. Kühn S, Gleich T, Lorenz RC, Lindenberger U, Gallinat J. Playing Super Mario induces structural brain plasticity: grey matter changes resulting from training with a commercial video game. Mol Psychiatry. 2014;19(2)265-271.
4. Armstrong RJ, Barker RA. Neurodegeneration: a failure of neuroregeneration? Lancet. 2001;358 (9288):1174-1176.
5. Heinz A. Dopaminergic dysfunction in alcoholism and schizophrenia: psychopathological and behavioral correlates. Eur Psychiatry. 2002;17 (1):9-16.
6. Sullivan EV, Pfefferbaum A. Neurocircuitry in alcoholism: a substrate of disruption and repair. Psychopharmacology (Berl). 2005;180(4):583-594.
7. Brandt J, Butters N, Ryan C, Bayog R. Cognitive loss and recovery in long-term alcohol abusers. Arch Gen Psychiatry. 1983;40(4):435-442.
8. Stephens DN, Ripley TL, Borlikova G, et al. Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus. Biol Psychiatry. 2005;58(5):392-400.
9. Agartz I, Momenan R, Rawlings RR, KerichMJ, Hommer DW. Hippocampal volume in patients with alcohol dependence. Arch Gen Psychiatry. 1999;56 (4):356-363.
10. Bleich S, SperlingW, Degner D, et al. Lack of association between hippocampal volume reduction and first-onset alcohol withdrawal seizure: a volumetric MRI study. Alcohol Alcohol. 2003;38(1):40-44.
11. Geuze E, Vermetten E, Bremner JD.MR-based in vivo hippocampal volumetrics: findings in neuropsychiatric disorders. Mol Psychiatry. 2005; 10(2):160-184.
12. Laakso MP, Vaurio O, Savolainen L, et al. A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism. Behav Brain Res. 2000;109(2): 177-186.
13. Nagel BJ, Schweinsburg AD, Phan V, Tapert SF. Reduced hippocampal volume among adolescents with alcohol use disorders without psychiatric comorbidity. Psychiatry Res. 2005;139(3):181-190.
14. Oscar-Berman M, Song J. Brain volumetric measures in alcoholics: a comparison of two segmentationmethods. Neuropsychiatr Dis Treat. 2011;7:65-75.
15. Lee E, Jang DP, Kim JJ, et al. Alteration of brain metabolites in young alcoholics without structural changes. Neuroreport. 2007;18(14):1511-1514.
16. Walker DW, Barnes DE, Zornetzer SF, Hunter BE, Kubanis P. Neuronal loss in hippocampusinduced by prolonged ethanol consumption in rats. Science. 1980;209(4457):711-713.
17. Obernier JA, Bouldin TW, Crews FT. Binge ethanol exposure in adult rats causes necrotic cell death. Alcohol Clin Exp Res. 2002;26(4):547-557.
18. Pfefferbaum A, Sullivan EV, Mathalon DH, Shear PK, Rosenbloom MJ, Lim KO. Longitudinal changes in magnetic resonance imaging brain volumes in abstinent and relapsed alcoholics. Alcohol Clin Exp Res. 1995;19(5):1177-1191.
19. Carlen PL,Wortzman G, Holgate RC, Wilkinson DA, Rankin JC. Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans. Science. 1978;200 (4345):1076-1078.
20. Gazdzinski S, Durazzo TC, Yeh PH, Hardin D, Banys P, Meyerhoff DJ. Chronic cigarette smoking modulates injury and short-term recovery of the medial temporal lobe in alcoholics. Psychiatry Res. 2008;162(2):133-145.
21. Nixon K, Crews FT. Temporally specific burst in cell proliferation increases hippocampal neurogenesis in protracted abstinence from alcohol. J Neurosci. 2004;24(43):9714-9722.
22. Duvernoy HM. The Human Hippocampus. Berlin, Germany: Springer; 2005.
23. Spanagel R, Bartsch D, Brors B, et al. An integrated genome research network for studying the genetics of alcohol addiction. Addict Biol. 2010; 15(4):369-379.
24. First MB, Gibbon M. User's Guide for the Structured Clinical Interview for DSM-IV Axis I Disorders SCID-I. Arlington, VA: American Psychiatric Pub; 1997.
25. Babor TF, Higgins-Biddle JC. The Alcohol Use Disorders Identification Test. Geneva, Switzerland: World Health Organization; 2001.
26. Skinner HA. The drug abuse screening test. Addict Behav. 1982;7(4):363-371.
27. Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of alcohol withdrawal: the revised Clinical Institute Withdrawal Assessment for Alcohol scale (CIWA-Ar). Br J Addict. 1989;84(11):1353-1357.
28. Fischl B. Free Surfer. Neuroimage. 2012;62(2): 774-781.
29. Van Leemput K, Bakkour A, Benner T, et al. Automated segmentation of hippocampal subfields from ultra-high resolution in vivo MRI. Hippocampus. 2009;19(6):549-557.
30. Fischl B, Salat DH, Busa E, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron. 2002;33(3):341-355.
31. KingMA, Hunter BE,Walker DW. Alterations and recovery of dendritic spine density in rat hippocampus following long-term ethanol ingestion. Brain Res. 1988;459(2):381-385.
32. Lescaudron L, Jaffard R, Verna A. Modifications in number and morphology of dendritic spines resulting from chronic ethanol consumption and withdrawal: a Golgi study in the mouse anterior and posterior hippocampus. Exp Neurol. 1989;106(2): 156-163.
33. Cadete-Leite A, TavaresMA, Uylings HB, Paula-Barbosa M. Granule cell loss and dendritic regrowth in the hippocampal dentate gyrus of the rat after chronic alcohol consumption. Brain Res. 1988;473(1):1-14.
34. McMullen PA, Saint-Cyr JA, Carlen PL. Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal. J Comp Neurol. 1984;225(1):111-118.
35. Harper C.The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain? J Neuropathol Exp Neurol. 1998; 57(2):101-110.
36. Nixon K, Kim DH, Potts EN, He J, Crews FT. Distinct cell proliferation events during abstinence after alcohol dependence: microglia proliferation precedes neurogenesis. Neurobiol Dis. 2008;31(2): 218-229.
37. HallW, Zador D. The alcohol withdrawal syndrome. Lancet. 1997;349(9069):1897-1900.
38. DeWitte P, Pinto E, Ansseau M, Verbanck P. Alcohol and withdrawal: from animal research to clinical issues. Neurosci Biobehav Rev. 2003;27(3): 189-197.
39. Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. Neurosci. 1997;17(10): 3727-3738.
40. Parent JM, Lowenstein DH. Seizure-induced neurogenesis: are more new neurons good for an adult brain? Prog Brain Res. 2002;135:121-131.
41. Cameron HA, Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience. 1994;61(2):203-209.
42. Suri D, Vaidya VA.Glucocorticoid regulation of brain-derived neurotrophic factor: relevance to hippocampal structural and functional plasticity. Neuroscience. 2013;239:196-213.
43. Beresford TP, Arciniegas DB, Alfers J, et al. Hypercortisolism in alcohol dependence and its relation to hippocampal volume loss. J Stud Alcohol. 2006;67(6):861-867.
44. Stephens MAC,Wand G. Stress and the HPA axis: role of glucocorticoids in alcohol dependence. Alcohol Res. 2012;34(4):468-483.
45. Shors TJ, Miesegaes G, Beylin A, Zhao M, Rydel T, Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature. 2001;410 (6826):372-376.
46. Bartels C, Kunert HJ, Stawicki S, Kröner-Herwig B, Ehrenreich H, Krampe H. Recovery of hippocampus-related functions in chronic alcoholics during monitored long-term abstinence. Alcohol Alcohol. 2007;42(2):92-102.
47. Sullivan EV, Rosenbloom MJ, Lim KO, Pfefferbaum A. Longitudinal changes in cognition, gait, and balance in abstinent and relapsed alcoholic men: relationships to changes in brain structure. Neuropsychology. 2000;14(2):178-188.
48. Loeber S, Duka T,Welzel Márquez H, et al. Effects of repeated withdrawal from alcohol on recovery of cognitive impairment under abstinence and rate of relapse. Alcohol Alcohol. 2010;45(6): 541-547.
49. Seifert J, Seeland I, Borsutzky M, et al. Effects of acute alcohol withdrawal on memory performance in alcohol-dependent patients: a pilot study. Addict Biol. 2003;8(1):75-80.
50. Treves A, Rolls ET. Computational analysis of the role of the hippocampus in memory. Hippocampus. 1994;4(3):374-391.
51. O'Reilly RC, McClelland JL. Hippocampal conjunctive encoding, storage, and recall: avoiding a trade-off. Hippocampus. 1994;4(6):661-682.
52. Yassa MA, Stark CEL. Pattern separation in the hippocampus. Trends Neurosci. 2011;34(10):515-525.
53. Jones MW, McHugh TJ. Updating hippocampal representations: CA2 joins the circuit. Trends Neurosci. 2011;34(10):526-535.
54. Sekino Y, Shirao T. A role for signal propagation through the hippocampal CA2 field in memory formation. In: Zhong N, Liu J, Yao Y,Wu J, Lu S, Li K, eds. Lecture Notes in Computer Science. Berlin, Germany: Springer Berlin Heidelberg; 2007:254-266.