Developmental bisphenol-A exposure affects hippocampal dentate gyrus area spine formation through Wnt/β-catenin signaling

Chinese Journal of Pharmacology and Toxicology

Volumn 28, Issue 2, 2014, Pages 161-167

  Liu, Zhi Hua ^a   Wang, Hui Li ^a   Wu, Sheng ^b   Liu, Yang ^b   Chen, Xiang Tao ^b  

^a HEFEI UNIVERSITY OF TECHNOLOGY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Bisphenol A; Dendritic spine; Synapse formation; Wnt signaling

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; BETA CATENIN; WNT5A PROTEIN; WNT7A PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; DENTATE GYRUS; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; GOLGI STAIN; HIPPOCAMPUS; NONHUMAN; PERINATAL PERIOD; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SPINE; SYNAPSE; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

EID: 84903834392     PISSN: 10003002     EISSN: None     Source Type: Journal    
DOI: 10.3867/j.issn.1000-3002.2014.02.003     Document Type: Article

References (23)

1. Vandenberg LN, Hauser R, Marcus M, Olea N, Welshons WV. Human exposure to bisphenol A (BPA) [J]. Reprod Toxicol, 2007, 24(2): 139-177. (Pubitemid 47385100)
2. Kandaraki E, Chatzigeorgiou A, Livadas S, Palioura E, Economou F, Koutsilieris M, et al. Endocrine disruptors and polycystic ovary syndrome (PCOS): elevated serum levels of bisphenol A in women with PCOS[J]. J Clin Endocrinol Metab, 2011, 96(3): E480-E484.
3. Braun JM, Kalkbrenner AE, Calafat AM, Yolton K, Ye X, Dietrich KN, et al. Impact of early-life bisphenol A exposure on behavior and executive function in children [J]. Pediatrics, 2011, 128(5): 873-882.
4. Luine VN. Sex steroids and cognitive function[J]. J Neuroendocrinol, 2008, 20(6): 866-872. (Pubitemid 351858740)
5. Eilam-Stock T, Serrano P, Frankfurt M, Luine V. Bisphenol-A impairs memory and reduces dendritic spine density in adult male rats [J]. Behav Neurosci, 2012, 126(1): 175-185.
6. Saab BJ, Georgiou J, Nath A, Lee FJ, Wang M, Michalon A, et al. NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory [J]. Neuron, 2009, 63(5): 643-656.
7. Amaral DG, Scharfman HE, Lavenex P. The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) [J]. Prog Brain Res, 2007, 163: 3-22.
8. Koehl M, Abrous DN. A new chapter in the field of memory: adult hippocampal neurogenesis [J]. Eur J Neurosci, 2011, 33(6): 1101-1114.
9. Bayer SA, Altman J. Hippocampal development in the rat: cytogenesis and morphogenesis examined with autoradiography and low-level X-irradiation [J]. J Comp Neurol, 1974, 158(1): 55-79.
10. Hiester BG, Galati DF, Salinas PC, Jones KR. Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation[J]. Mol Cell Neurosci, 2013, 56: 115-127.
11. 2+/calmodulin-dependent protein kinase II [J]. Proc Natl Acad Sci USA, 2011, 108(26): 10732-10737.
12. A receptors on hippocampal neurons [J]. J Neurosci, 2010, 30(25): 8411-8420.
13. Kubo K, Arai O, Ogata R, Omura M, Hori T, Aou S. Exposure to bisphenol A during the fetal and suckling periods disrupts sexual differentiation of the locus coeruleus and of behavior in the rat [J]. Neurosci Lett, 2001, 304(1-2): 73-76. (Pubitemid 32373319)
14. Rice D, Barone S Jr. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models [J]. Environ Health Perspect, 2000, 108(Suppl 3): 511-533. (Pubitemid 30466179)
15. Hosokawa T, Rusakov DA, Bliss TV, Fine A. Repeated confocal imaging of individual dendritic spines in the living hippocampal slice: evidence for changes in length and orientation associated with chemically induced LTP [J]. J Neurosci, 1995, 15(8): 5560-5573.
16. González-Ramírez MM, Velázquez-Zamora DA, Olvera-Cortés ME, González-Burgos I. Changes in the plastic properties of hippocampal dendritic spines underlie the attenuation of place learning in healthy aged rats [J]. Neurobiol Learn Mem, 2014, 109: 94-103.
17. Schmitz Y, Rateitschak K, Wolkenhauer O. Analysing the impact of nucleo-cytoplasmic shuttling of β-catenin and its antagonists APC, Axin and GSK3 on Wnt/β-catenin signalling [J]. Cell Signal, 2013, 25(11): 2210-2221.
18. Yang J, Zhang W, Evans PM, Chen X, He X, Liu C. Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells [J]. J Biol Chem, 2006, 281(26): 17751-17757. (Pubitemid 44035574)
19. Dominguez I, Itoh K, Sokol SY. Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos [J]. Proc Natl Acad Sci USA, 1995, 92(18): 8498-8502.
20. Yu X, Malenka RC. Beta-catenin is critical for dendritic morphogenesis [J]. Nat Neurosci, 2003, 6(11): 1169-1677.
21. Ahmad-Annuar A, Ciani L, Simeonidis I, Herreros J, Fredj NB, Rosso SB, et al. Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release [J]. J Cell Biol, 2006, 174(1): 127-139. (Pubitemid 43992902)
22. Li J, Ying J, Fan Y, Wu L, Ying Y, Chan AT, et al. WNT5A antagonizes WNT/β-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma [J]. Cancer Biol Ther, 2010, 10(6): 617-624.
23. Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context [J]. PLoS Biol, 2006, 4(4): e115.