Genome-wide normalized score: A novel algorithm to detect fetal trisomy 21 during non-invasive prenatal testing

Ultrasound in Obstetrics and Gynecology

Volumn 44, Issue 1, 2014, Pages 25-30

  Yeang, C H ^a   Ma, G C ^b,c   Hsu, H W ^b   Lin, Y S ^d   Chang, S M ^b   Cheng, P J ^e   Chen, C A ^f   Ni, Y H ^f   Chen, M ^b,f,g,h  

^a INSTITUTE OF STATISTICAL SCIENCE   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d Welgene Biotech Co Ltd   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^g NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^h TUNGHAI UNIVERSITY   (Taiwan)

Author keywords

genome wide; MPSS; NIPT; plasma DNA; statistical algorithm

Indexed keywords

ALGORITHM; BIOLOGY; CASE CONTROL STUDY; COMPARATIVE STUDY; DNA SEQUENCE; DOWN SYNDROME; EVALUATION STUDY; FEMALE; GENETIC SCREENING; HIGH THROUGHPUT SEQUENCING; HUMAN; MATERNAL SERUM SCREENING TEST; PREGNANCY; PROCEDURES; RECEIVER OPERATING CHARACTERISTIC;

ALGORITHMS; CASE-CONTROL STUDIES; COMPUTATIONAL BIOLOGY; DOWN SYNDROME; FEMALE; GENETIC TESTING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MATERNAL SERUM SCREENING TESTS; PREGNANCY; ROC CURVE; SEQUENCE ANALYSIS, DNA;

EID: 84903816742     PISSN: 09607692     EISSN: 14690705     Source Type: Journal    
DOI: 10.1002/uog.13377     Document Type: Article

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