Incidental magnetic resonance diffusion-weighted imaging-positive lesions are rare in neurologically asymptomatic community-dwelling adults

Stroke

Volumn 45, Issue 7, 2014, Pages 2115-2117

  Batool, Saima ^a   O'Donnell, Martin ^b   Sharma, Mukul ^b   Islam, Shofiqul ^b   Dagenais, Gilles R ^c   Poirier, Paul ^c   Lear, Scott A ^d,e   Wielgosz, Andreas ^f   Teo, Koon ^b   Stotts, Grant ^f   McCreary, Cheryl R ^a,g   Frayne, Richard ^a,g,h   Dejesus, Jane ^b   Rangarajan, Sumathy ^b   Yusuf, Salim ^b   Smith, Eric E ^a,g,h  

^a UNIVERSITY OF CALGARY   (Canada)

^b HAMILTON HEALTH SCIENCES   (Canada)

^c LAVAL UNIVERSITY   (Canada)

^d SIMON FRASER UNIVERSITY   (Canada)

^e Division of Cardiology   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

^g ALBERTA HEALTH SERVICES   (Canada)

^h UNIVERSITY OF CALGARY   (Canada)

Author keywords

magnetic resonance imaging; stroke

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; COMMUNITY LIVING; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; INCIDENTAL FINDING; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; VASCULAR AMYLOIDOSIS;

MAGNETIC RESONANCE IMAGING; STROKE;

ADULT; AGED; CANADA; CEREBRAL INFARCTION; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES;

EID: 84903787187     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.005782     Document Type: Article

References (11)

1. Smith EE, Schneider JA, Wardlaw JM, Greenberg SM. Cerebral microinfarcts: the invisible lesions. Lancet Neurol. 2012;11: 272-282.
2. Kimberly WT, Gilson A, Rost NS, Rosand J, Viswanathan A, Smith EE, et al. Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology. 2009;72: 1230-1235.
3. Menon RS, Burgess RE, Wing JJ, Gibbons MC, Shara NM, Fernandez S, et al. Predictors of highly prevalent brain ischemia in intracerebral hemorrhage. Ann Neurol. 2012;71: 199-205.
4. Auriel E, Martinez-Ramirez S, Gurol ME, Schwab K, Edlow B, Boulouis G, et al. Incidental diffusion-weighted imaging lesions in patients with cognitive decline. Stroke. 2013;44:AWMP116.
5. Saini M, Ikram K, Hilal S, Qiu A, Venketasubramanian N, Chen C. Silent stroke: not listened to rather than silent. Stroke. 2012;43: 3102-3104.
6. Westover MB, Bianchi MT, Yang C, Schneider JA, Greenberg SM. Estimating cerebral microinfarct burden from autopsy samples. Neurology. 2013;80: 1365-1369.
7. Teo K, Chow CK, Vaz M, Rangarajan S, Yusuf S; PURE Investigators- Writing Group. The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries. Am Heart J. 2009;158:1.e1-7.e1.
8. Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, et al; STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013;12: 822-838.
9. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR Am J Roentgenol. 1987;149: 351-356. (Pubitemid 17104996)
10. Yamada K, Nagakane Y, Sasajima H, Nakagawa M, Mineura K, Masunami T, et al. Incidental acute infarcts identified on diffusion-weighted images: A university hospital-based study. AJNR Am J Neuroradiol. 2008;29: 937-940. (Pubitemid 351684970)
11. van Veluw SJ, Zwanenburg JJ, Engelen-Lee J, Spliet WG, Hendrikse J, Luijten PR, et al. In vivo detection of cerebral cortical microinfarcts with high-resolution 7T MRI. J Cereb Blood Flow Metab. 2013;33: 322-329.