Doxepin rinse versus placebo in the treatment of acute oral mucositis pain in patients receiving head and neck radiotherapy with or without chemotherapy: A phase III, randomized, double-blind trial (NCCTG-N09C6 [Alliance])

Journal of Clinical Oncology

Volumn 32, Issue 15, 2014, Pages 1571-1577

  Leenstra, James L ^a   Miller, Robert C ^b   Qin, Rui ^b   Martenson, James A ^b   Dornfeld, Kenneth J ^c   Bearden, James D ^d   Puri, Dev R ^e   Stella, Philip J ^f   Mazurczak, Miroslaw A ^g   Klish, Marie D ^h   Novotny, Paul J ^b   Foote, Robert L ^b   Loprinzi, Charles L ^b  

^a Saint Vincent Regional Cancer Center   (United States)

^b MAYO CLINIC   (United States)

^c Essentia Health   (United States)

^d PA   (United States)

^e Mercy Medical Center   (United States)

^f Saint Joseph Mercy Health System   (United States)

^g Sandford Health Cancer Center   (United States)

^h Hope Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXEPIN; PLACEBO; ANALGESIC AGENT; MOUTHWASH;

ACUTE DISEASE; ADULT; AREA UNDER THE CURVE; ARTICLE; BURN; BURNING DISCOMFORT; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG EFFICACY; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUTH PAIN; MULTIMODALITY CANCER THERAPY; ORAL MUCOSITIS; ORAL MUCOSITIS PAIN; PAIN ASSESSMENT; PERSONAL EXPERIENCE; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SORE THROAT; TASTE; UNPLEASANT TASTE; AGED; CHEMICALLY INDUCED DISORDER; CHEMORADIOTHERAPY; CONTROLLED CLINICAL TRIAL; CROSSOVER PROCEDURE; FACE PAIN; HEAD AND NECK TUMOR; MIDDLE AGED; MULTICENTER STUDY; PAIN; PREDICTIVE VALUE; SKULL IRRADIATION; STOMATITIS; TIME; TREATMENT OUTCOME; UNITED STATES; VERY ELDERLY;

ACUTE PAIN; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS; AREA UNDER CURVE; CHEMORADIOTHERAPY; CRANIAL IRRADIATION; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DOXEPIN; FACIAL PAIN; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MOUTHWASHES; PAIN MEASUREMENT; PREDICTIVE VALUE OF TESTS; QUESTIONNAIRES; STOMATITIS; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES;

EID: 84903777868     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.53.2630     Document Type: Article

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