SGLT inhibition in patients with type 1 diabetes

The Lancet Diabetes and Endocrinology

Volumn 2, Issue 7, 2014, Pages 539-

  Dehn, Clayton A ^a  

^a CELERION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; INSULIN; SODIUM GLUCOSE COTRANSPORTER INHIBITOR; ANTIDIABETIC AGENT; SODIUM GLUCOSE COTRANSPORTER;

DIABETIC KETOACIDOSIS; EUGLYCEMIC DIABETIC KETOACIDOSIS; GLYCEMIC CONTROL; HUMAN; HYPERGLYCEMIA; HYPOINSULINEMIA; INSULIN DEPENDENT DIABETES MELLITUS; KETONURIA; LETTER; MEDICATION COMPLIANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT COMPLIANCE; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; DIABETES MELLITUS, TYPE 1;

DIABETES MELLITUS, TYPE 1; HUMANS; HYPOGLYCEMIC AGENTS; SODIUM-GLUCOSE TRANSPORT PROTEINS;

EID: 84903768473     PISSN: 22138587     EISSN: 22138595     Source Type: Journal    
DOI: 10.1016/S2213-8587(14)70112-3     Document Type: Letter

References (5)

1. Henry RR, Rosenstock J, Chalamandris A-G, Kasichayanula S, Bogle A, Griffen SC. Exploring the potential of dapagliflozin in type 1 diabetes: phase 2a pilot study. 73rd American Diabetes Association Scientific Sessions; Chicago, IL, USA; June 21-25, 2013; 70-LB.
2. Perkins BA, Cherney DZ, Partridge H, et al. The sodium glucose cotransporter 2 (SGLT2) inhibitor empagliflozin improves glycemic control in patients with type 1 diabetes: a single-arm clinical trial. 73rd American Diabetes Association Scientific Sessions; Chicago, IL, USA; June 21-25, 2013; 1074-P.
3. LX4211 achieves positive results in type 1 diabetes clinical trial. 2013. Press release Lexicon Pharmaceuticals, (accessed April 29, 2014. http://www.lexgen.com/news/press-releases/2321-lx4211-achieves-positive-results-in-type-1-diabetes-clinical-trial.html.
4. Ferrannini E, Muscelli E, Frascerra S, et al. Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. J Clin Invest 2014, 124:499-508.
5. Mervoci A, Solis-Herrera C, Daniele G, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest 2014, 124:509-514.