Study on gallic acid induced human hepatoma SMMC-7721 cells apoptosis and its mechanism

Chinese Pharmacological Bulletin

Volumn 30, Issue 5, 2014, Pages 657-661

  Li, Mu Han ^a   Wang, Ming Yan ^a   Zhao, Feng Ming ^a   Chen, Hai Bin ^a   Zhou, Hong Guang ^a   Zhao, Qing Chun ^a   Li, Wen Ting ^a   Wu, Mian Hua ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Cell apoptosis; Gallic acid; Hepatoma; Proliferation; SMMC 7721 cells; Tumor suppressor gene p53

Indexed keywords

GALLIC ACID; LIPOCORTIN 5; MESSENGER RNA; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84903756157     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1001-1978.2014.05.015     Document Type: Article

References (15)

1. Shariff M I, Cox I J, Gomaa A I, et al. Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics[J]. Expert Rev Gastroenterol Hepatol, 2009,3(4):353-67.
2. Du W F, Zhang Y, Cai B C, et al. Analysis on active components in crude and processed cornus officinals by HPLC-ESI-MS [J]. Chin Arch Tradit Chin Med, 2012,30(1):62-5.
3. Wang Q, Zhang N N, Gao J, et al. Active ingredients in rhubarb with anti-proliferative effects on scar fibroblasts[J]. Pharmaceut J, 2012,47(12):1618-22.
4. Wei S S, He J B, Yan Y M, Studies on plant source chemical constituents of Tenodera sinensis Saussure egg [J]. J Pharm Res, 2013,32(3):128-30.
5. Zhong Z G, Zhong Y N, Zhang W Y, et al. Experimental study on antitumor effect of Gallic acid in vitro [J]. Li shi zhen Med Mat Med Res, 2009,20(8):1954-5.
6. Mirvish S S, Cardesa A, Wallcave L, et al. Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine[J]. Natl Cancer Inst, 1975,55(3):633-6.
7. Veluri R, Singh R P, Liu Z, et al. Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells [J]. Carcinogenesis, 2006,27(7):1445-53. (Pubitemid 43985419)
8. Li M H, Zhao F M, Wang M Y, et al. Antitumor mechanism of gallic acid on gastric cancer cell lines MGC-803 in vitro[J]. Tradit Chin Drug Res Clin Pharmacol, 2011,22(1):37-40.
9. Hsu C L, Lo W H, Yen G C. Gallic acid induces apoptosis in 3T3-L1 pre-adipocytes via a Fas-and mitochondrial-mediated pathway [J]. Agric Food Chem, 2007,55(18):7359-65.
10. Mahassni S H, AL-Reemi R M. Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds [J]. Saudi J Biol Sci, 2013,20(2):131-9.
11. Liu J J, Yang C L, Jiang J H, et al. Mechanism of SGC-7901 apoptosis induced by Houttuynia cordata thunb subterraneous stem extraction [J]. Chin Pharmacol Bull, 2014,30(2):257-61.
12. Yu C, Qiu Z Y, Li H Z, et al. Mechanisms of apoptosis induced by tubeimosides in human rectal cancer cell line SW 480 in vitro [J]. Chin Pharmacol Bull, 2006,22(7):880-4. (Pubitemid 44594549)
13. Ecke T H, Schlechte H H, Schiemenz K, et al. TP53 gene mutations in prostate cancer progression [J]. Anticancer Res, 2010,30(5):1579-86.
14. Ozaki T, Nakagawara A. p53: the attractive tumor suppressor in the cancer research field [J]. J Biomed Biotechnol, 2011,2011:603925.
15. Ventura A, Kirsch D G, McLaughlin M E, et al. Restoration of p53 function leads to tumour regression in vivo[J]. Nature, 2007,445(7128):661-5. (Pubitemid 46232887)