Pharmacological inhibition of bromodomain-containing proteins in inflammation

Cold Spring Harbor Perspectives in Biology

Volumn 6, Issue 6, 2014, Pages

  Schaefer, Uwe ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; PROTEIN;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; INFLAMMATION;

ANTI-INFLAMMATORY AGENTS; INFLAMMATION; PROTEINS;

EID: 84903746848     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a018671     Document Type: Article

References (8)

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3. Hargreaves DC, Horng T, Medzhitov R. 2009. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138: 129-145.
4. Medzhitov R, Horng T. 2009. Transcriptional control of the inflammatory response. Nat Rev Immunol 9: 692-703.
5. Nathan C. 2002. Points of control in inflammation.Nature 420: 846-852.
6. Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung C-W, Chandwani R, Marazzi I, Wilson P, Coste H, et al. 2010. Suppression of inflammation by a synthetic histone mimic. Nature 468: 1119-1123.
7. Qi J. 2014. Bromodomain and extraterminal domain inhibitors (BETi) for cancer therapy: Chemical modulation of chromatin structure. Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect.a018663.
8. Smale ST. 2010. Selective transcription in response to an inflammatory stimulus. Cell 140: 833-844.