A novel silk-based artificial ligament and tricalcium phosphate/polyether ether ketone anchor for anterior cruciate ligament reconstruction - Safety and efficacy in a porcine model

Acta Biomaterialia

Volumn 10, Issue 8, 2014, Pages 3696-3704

  Li, Xiang ^a,b   He, Jiankang ^c   Bian, Weiguo ^d   Li, Zheng ^e   Zhang, Wenyou ^c   Li, Dichen ^c   Snedeker, Jess G ^a,b  

^a BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d First Hosp of Xi'an Jiaotong Univ   (China)

^e FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

ACL reconstruction; Artificial ACL; PEEK; Silk; TCP

Indexed keywords

ETHERS; KETONES; SILK; TENSILE STRENGTH; TRANSMISSION CONTROL PROTOCOL;

ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT GRAFT; ANTERIOR-CRUCIATE-LIGAMENT RECONSTRUCTION; ARTIFICIAL ANTERIOR CRUCIATE LIGAMENT; ARTIFICIAL LIGAMENTS; GRAFT TENSIONS; HOST TISSUES; PORCINE MODELS; SILK; TRI-CALCIUM PHOSPHATES;

BONE;

CALCIUM PHOSPHATE; PENICILLIN DERIVATIVE; PETHIDINE; POLYETHERETHERKETONE; SILK; KETONE; MACROGOL DERIVATIVE;

ADHESION; ADULT; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ANTIBIOTIC PROPHYLAXIS; ARTICLE; AUTOGRAFT; BIOMECHANICS; CONTROLLED STUDY; FIBROCARTILAGE; HISTOLOGY; INFECTION PREVENTION; INTERFERENCE SCREW; MALE; NONHUMAN; PORCINE MODEL; POSTOPERATIVE INFECTION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SWINE; TENSILE STRENGTH; ANIMAL; BIOPROSTHESIS; CHEMISTRY; DEVICE FAILURE ANALYSIS; DEVICES; GROWTH, DEVELOPMENT AND AGING; HUMAN; INJURIES; MATERIALS TESTING; PATHOLOGY; PIG; PROCEDURES; PROSTHESIS; TISSUE REGENERATION; TISSUE SCAFFOLD; TREATMENT OUTCOME;

ANIMALIA; SUS;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; BIOPROSTHESIS; CALCIUM PHOSPHATES; EQUIPMENT FAILURE ANALYSIS; GUIDED TISSUE REGENERATION; HUMANS; KETONES; MATERIALS TESTING; POLYETHYLENE GLYCOLS; PROSTHESIS DESIGN; SILK; SWINE; TISSUE SCAFFOLDS; TREATMENT OUTCOME;

EID: 84903745842     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.05.015     Document Type: Article

References (46)

1. J. Parkkari, K. Pasanen, V.M. Mattila, P. Kannus, and A. Rimpelae The risk for a cruciate ligament injury of the knee in adolescents and young adults: a population-based cohort study of 46,500 people with a 9 year follow-up Brit J Sport Med 42 6 2008 422 426
2. J.W. Freeman, and A.L. Kwansa Recent advancements in ligament tissue engineering: the use of various techniques and materials for ACL repair Recent Pat Biomed Eng 1 1 2008 18 23
3. D. Junkin, D. Johnson, F. Fu, M. Mark, M. Willenborn, and G. Fanelli et al. Knee ligament injuries. Orthopaedic knowledge update: sports medicine 2009 American Academy of Orthopaedic Surgeons Rosemont, IL [p. 136]
4. K. Chen, S. Sahoo, P. He, K.S. Ng, S.L. Toh, and J.C. Goh A hybrid silk/RADA-based fibrous scaffold with triple hierarchy for ligament regeneration Tissue Eng A 18 13-14 2012 1399 1409
5. M.M. Murray History of ACL treatment and current gold standard of care The ACL handbook 2013 Springer New York 19 28
6. M.S.J. Hospodar, and M.D. Miller Controversies in ACL reconstruction: bone-patellar tendon-bone anterior cruciate ligament reconstruction remains the gold standard Sports Med Arthrosc Rev 17 4 2009 242 246
7. M. Lind, B. Lund, P. Faunø, S. Said, L.L. Miller, and S.E. Christiansen Medium to long-term follow-up after ACL revision Knee Surg Sports Traumatol Arthrosc 20 1 2012 166 172
8. T. Gifstad, A. Sole, T. Strand, G. Uppheim, T. Grøntvedt, and J.O. Drogset Long-term follow-up of patellar tendon grafts or hamstring tendon grafts in endoscopic ACL reconstructions Knee Surg Sports Traumatol Arthrosc 2012 1 8
9. S. Bernardino ACL prosthesis: any promise for the future? Knee Surg Sports Traumatol Arthrosc 18 6 2010 797 804
10. K. Samuelsson, D Andersson, M. Ahldén, F.H. Fu, V. Musahl, and J. Karlsson Trends in surgeon preferences on anterior cruciate ligament reconstructive techniques Clin Sports Med 32 1 2013 111 126
11. M.P. Arnold, D.T. Lie, N. Verdonschot, R de Graaf, A.A. Amis, and A. van Kampen The remains of anterior cruciate ligament graft tension after cyclic knee motion Am J Sports Med 33 4 2005 536 542
12. V. Sanchis-Alfonso, E. Montesinos-Berry, A. Subías-López, and J.C. Monllau Anterior knee pain after ACL reconstruction: how to avoid it The ACL-deficient knee 2013 Springer London 357 372
13. J.A. Baumfeld, D.R. Diduch, L.J. Rubino, J.A. Hart, M.D. Miller, and M.S. Barr et al. Tunnel widening following anterior cruciate ligament reconstruction using hamstring autograft: a comparison between double cross-pin and suspensory graft fixation Knee Surg Sports Traumatol Arthrosc 16 12 2008 1108 1113
14. H.F. Liu, H.B. Fan, S.L. Toh, and J.C.H. Goh A comparison of rabbit mesenchymal stem cells and anterior cruciate ligament fibroblasts responses on combined silk scaffolds Biomaterials 29 10 2008 1443 1453
15. H.B. Fan, H.F. Liu, S.L. Toh, and J.C.H. Goh Anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold in large animal model Biomaterials 30 28 2009 4967 4977
16. D.I. Zeugolis, J.C.Y. Chan, and A. Pandit Tendons: engineering of functional tissues Tissue engineering 2011 Springer Berlin Heidelberg 537 572
17. G.H. Altman, R.L. Horan, H.H. Lu, J. Moreau, I. Martin, and J.C. Richmond et al. Silk matrix for tissue engineered anterior cruciate ligaments Biomaterials 23 20 2002 4131 4141
18. G.H. Altman, F. Diaz, C. Jakuba, T. Calabro, R.L. Horan, and J.S. Chen et al. Silk-based biomaterials Biomaterials 24 3 2003 401 416
19. R.L. Horan, A.L. Collette, C. Lee, K. Antle, J.S. Chen, and G.H. Altman Yarn design for functional tissue engineering J Biomech 39 12 2006 2232 2240
20. G.H. Altman, R.L. Horan, P. Weitzel, and J.C. Richmond The use of long-term bioresorbable scaffolds for anterior cruciate ligament repair J Am Acad Orthop Surg 16 4 2008 177 187
21. R.L. Horan, D.S. Bramono, J.R.L. Stanley, Q. Simmons, J. Chen, and H.E. Boepple et al. Biological and biomechanical assessment of a long-term bioresorbable silk-derived surgical mesh in an abdominal body wall defect model Hernia 13 2 2009 189 199
22. E. Panas-Perez, C. Gatt, and M. Dunn Development of a silk and collagen fiber scaffold for anterior cruciate ligament reconstruction J Mater Sci Mater Med 24 1 2013 257 265
23. T.K.H. Teh, J.C.H. Goh, and S.L. Toh Characterization of electrospun substrates for ligament regeneration using bone marrow stromal cells 13th International Conference on Biomedical Engineering 2009 Springer Berlin Heidelberg
24. R.L. Horan SeriACL™ device (Gen IB) trial for anterior cruciate ligament (ACL) repair 2009 Serica Technologies, Inc. Medford, MA [NCT00775892]
25. J. Lei, and J.S. Temenoff Engineering fibrous tissues and their interfaces with bone Structural interfaces and attachments in biology 2013 Springer New York 323 349
26. P. He, K.S. Ng, S.L. Toh, and J.C.H. Goh In vitro ligament-bone interface regeneration using a trilineage coculture system on a hybrid silk scaffold Biomacromolecules 13 9 2012 2692 2703
27. M.Y.H. Soon, A. Hassan, J.H.R. Hui, J.C.H. Goh, and E.H. Lee An analysis of soft tissue allograft anterior cruciate ligament reconstruction in a rabbit model - a short-term study of the use of mesenchymal stem cells to enhance tendon osteointegration Am J Sports Med 35 6 2007 962 971
28. J. Lee, W. Choi Il, G. Tae, Y.H. Kim, S.S. Kang, and S.E. Kim et al. Enhanced regeneration of the ligament-bone interface using a poly(l-lactide-co-epsilon-caprolactone) scaffold with local delivery of cells/BMP-2 using a heparin-based hydrogel Acta Biomater 7 1 2011 244 257
29. H.M. Kim, L.M. Galatz, R. Das, N. Havlioglu, S.Y. Rothermich, and S. Thomopoulos The role of transforming growth factor beta isoforms in tendon-to-bone healing Connect Tissue Res 52 2 2011 87 98
30. S.V. Dorozhkin Bioceramics of calcium orthophosphates Biomaterials 31 7 2010 1465 1485
31. M. Farshad, R.A. Weinert-Aplin, M. Stalder, P.P. Koch, J.G. Snedeker, and D.C. Meyer Embossing of a screw thread and TCP granules enhances the fixation strength of compressed ACL grafts with interference screws Knee Surg Sports Traumatol Arthrosc 20 2 2012 268 274
32. P. Shi, T.K. Teh, S.L. Toh, and J.C. Goh Variation of the effect of calcium phosphate enhancement of implanted silk fibroin ligament bone integration Biomaterials 34 24 2013 5947 5957
33. X. Li, J. He, W. Bian, Z. Li, D. Li, and J.G. Snedeker A novel silk-TCP-PEEK construct for anterior cruciate ligament reconstruction: an off-the-shelf alternative to a bone-tendon-bone autograft Biofabrication 6 1 2014 015010
34. X. Li, and J.G. Snedeker Wired silk architectures provide a biomimetic ACL tissue engineering scaffold J Mech Behav Biomed Mater 22 2013 30 40
35. X. Li, and J. Snedeker Long term mechanical behavior of silk ACL scaffolds under cyclic loading J Biomech 45 2012 S325
36. X. Li, W. Bian, D. Li, Q. Lian, and Z. Jin Fabrication of porous beta-tricalcium phosphate with microchannel and customized geometry based on gel-casting and rapid prototyping Proc Inst Mech Eng [H] 225 H3 2011 315 323
37. S.D. Coleridge, and A.A. Amis A comparison of five tibial-fixation systems in hamstring-graft anterior cruciate ligament reconstruction Knee Surg Sports Traumatol Arthrosc 12 5 2004 391 397
38. B.L. Proffen, and M.M. Murray In vivo models of ACL injury (central defect, porcine, ovine, canine) The ACL handbook 2013 Springer New York 139 166
39. N. Schmitz, S. Laverty, V. Kraus, and T. Aigner Basic methods in histopathology of joint tissues Osteoarthritis Cartilage 18 2010 S113 S116
40. S. Sahoo, S.L. Toh, and J.C. Goh A bFGF-releasing silk/PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells Biomaterials 31 11 2010 2990 2998
41. P. Vavken, B.C. Fleming, A.N. Mastrangelo, J.T. Machan, and M.M. Murray Biomechanical outcomes after bioenhanced anterior cruciate ligament repair and anterior cruciate ligament reconstruction are equal in a porcine model Arthroscopy 28 5 2012 672 680
42. G. Milano, P.D. Mulas, F. Ziranu, L. Deriu, and C. Fabbriciani Comparison of femoral fixation methods for anterior cruciate ligament reconstruction with patellar tendon graft: a mechanical analysis in porcine knees Knee Surg Sports Traumatol Arthrosc 15 6 2007 733 738
43. H.F. Liu, H.B. Fan, S.L. Toh, and J.C.H. Goh In Vivo Study of ACL Regeneration Using Silk Scaffolds In a Pig Model Ifmbe Proc. 23 1-3 2009 1512 1514
44. T.K.H. Teh, S.L. Toh, and J.C.H. Goh Aligned hybrid silk scaffold for enhanced differentiation of mesenchymal stem cells into ligament fibroblasts Tissue Eng Part C Methods 17 6 2011 687 703
45. X. Huangfu, and J. Zhao Tendon-bone healing enhancement using injectable tricalcium phosphate in a dog anterior cruciate ligament reconstruction model Arthroscopy 23 5 2007 455 462
46. S. Thomopoulos, H.M. Kim, M.J. Silva, E. Ntouvali, C.N. Manning, and R. Potter et al. Effect of bone morphogenetic protein 2 on tendon-to-bone healing in a canine flexor tendon model J Orthopaedic Res 30 11 2012 1702 1709