Reductions in the expression of miR-124-3p, miR-128-1, and miR-221-3p in pediatric astrocytomas are related to high-grade supratentorial, and recurrent tumors in Mexican children

Child's Nervous System

Volumn 30, Issue 7, 2014, Pages 1173-1181

  Eguía Aguilar, Pilar ^a,b   Pérezpeña Díazconti, Mario ^a   Benadón Darszon, Eduardo ^a   Chico Ponce De León, Fernando ^a   Gordillo Domínguez, Luis ^a   Torres García, Samuel ^a   Sadowinski Pine, Stanislaw ^a   Arenas Huertero, Francisco ^a  

^a HOSPITAL INFANTIL DE MÉXICO FEDERICO GÓMEZ   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Central nervous system tumors; microRNA; miRNA; Pediatric astrocytoma; Pediatric glioma

Indexed keywords

MICRO RNA 124 3P; MICRORNA; MICRORNA 128 1; MICRORNA 137; MICRORNA 15B; MICRORNA 181A 1; MICRORNA 21; MICRORNA 221 3P; MICRORNA 9; MICRORNA 9 1; PARAFFIN; UNCLASSIFIED DRUG; MIRN124 MICRORNA, HUMAN; MIRN128 MICRORNA, HUMAN; MIRN221 MICRORNA, HUMAN; TUMOR MARKER;

ADOLESCENT; ARTICLE; ASTROCYTOMA CELL LINE; BRAIN TISSUE; CELL PROLIFERATION; CHILD; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; MAJOR CLINICAL STUDY; MALE; MEXICO; PILOCYTIC ASTROCYTOMA; PRECURSOR; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR RECURRENCE; ASTROCYTOMA; BIOSYNTHESIS; BRAIN TUMOR; CANCER GRADING; GENE EXPRESSION PROFILING; GENETICS; PATHOLOGY; PRESCHOOL CHILD; REAL TIME POLYMERASE CHAIN REACTION;

ASTROCYTOMA; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INFANT; MALE; MEXICO; MICRORNAS; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84903594128     PISSN: 02567040     EISSN: 14330350     Source Type: Journal    
DOI: 10.1007/s00381-014-2416-5     Document Type: Article

References (37)

1. Bax D, Mackay A, Little S, Carvalho D, Viana-Pereira M, Tamber N, Grigoriadis A, Ashworth A, Reis R, Ellison D, Al-Sarraj S, Hargrave D, Jones C (2010) A distinct spectrum of copy number aberrations in paediatric high grade gliomas. Clin Cancer Res 16:3368-3377. doi: 10.1158/1078-0432.CCR-10-0438
2. Birks D, Barton V, Donson A, Handler M, Vibhakar R, Foreman N (2011) Survey of microRNA expression in pediatric brain tumors. Pediatr Blood Cancer 56:211-216. doi:10.1002/pbc.22723
3. Chan J, Krichevsky A, Kosik K (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033. doi:10.1158/0008-5472.CAN-05-0137 (Pubitemid 40994386)
4. Chico-Ponce de León F, Castro-Sierra E, Pérezpeña- Díazconti M, Gordillo-Domínguez L (2006) Tumores intracraneanos del niño. Bol Med Hosp Infan Mex 63:367-381
5. Cho W(2007) OncomiRs: the discovery and progress of microRNAs in cancers. Mol Cancer 6:60. doi:10.1186/1476-4598-6-60
6. Chung-sean J, Kei W, Chen Z, Ng H (2009) Oncogenic role of microRNAs in brain tumors. Acta Neuropathol 117:599-611. doi: 10.1007/s00401-009-0525-0
7. Ciafrè S, Galardi S, Mangiola A, Ferracin M, Liu C, Sabatino G, Negrini M, Maira G, Croce C, Faraceet M (2005) Extensive modulation of a set microRNAs in primary glioblastoma. Biochem Bioph Res Co 334:1351-1358. doi:10.1016/j.bbrc.2005.07.030 (Pubitemid 41074723)
8. Conti A, Aguennouz M, La Torre D, Tomasello C, Cardali S, Angileri F, Maio F, Cama A, Germano A, Vita G, Tomasello F (2009) MiR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors. J Neurooncol 93:325-332. doi:10.1007/s11060-009-9797-4
9. Deng S, Calin G, Croce C, Coukos G, Zhang L (2008) Mechanisms of microRNA deregulation in human cancer. Cell Cycle 7:2643-2646. doi:10.4161/cc.7.17.6597
10. Gillies J, Lorimer I (2007) Regulation of p27kip1 by miRNA 221/222 in glioblastoma. Cell Cycle 6:2005-2009. doi:10.4161/cc.6.16.4526 (Pubitemid 47327888)
11. Godlewski J, Newton H, Chiocca E, Lawler S (2010) MicroRNAs and glioblastoma; the stem cell connection. Cell Death Differ 17: 221-228. doi:10.1038/cdd.2009.71
12. Godlewski J, Nowicki M, Bronisz A, Williams S, Otsuki A, Nuovo G, RayChaudhury A, Newton H, Chiocca A, Lawleret S (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68:9125 - 9130. doi:10.1158/0008-5472.CAN-08-2629
13. Ho C, Bar E, Giannini C (2013) MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. Neuro Oncol 15:69-82. doi:10.1093/neuonc/nos269
14. Jiang L, Mao P, Song L (2010) MiR-182 as a prognostic marker for glioma progression and patients survival. Am J Pathol 177:29-37. doi:10.2353/ajpath. 2010.090812
15. Jin S, Sun C, Yu S, Wang Q, Wu W, Sun Y, Zhao W, An T (2010) Chromosome DNA imbalances in human astrocytic tumors: a comparative genomic hybridization study of 63 Chinese patients. Pathol Res Pract 206:674-681. doi:10.1016/j.prp. 2010.05.012
16. Kleihues P (2000) Astrocytic tumors. In: Kleihues P, Cavenee W (eds) Pathology & genetics of tumours of the nervous system, 3rd edn. IARC Press, Lyon, pp 9-51
17. Lakomy R, Sana J, Hankeova S (2011) MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients. Cancer Sci 102:2186-2190. doi:10.1111/j.1349-7006.2011.02092.x
18. Lantos P, Louis D, Rosenblum M, Kleihues P (2002) Tumours of the nervous system. In: Graham D, Lantos P (eds) Greenfield's neuropathology, 3rd edn. Arnold, London, pp 767-1052
19. Lee Y, Dutta A (2009) MicroRNAs in cancer. Annu Rev Pathol 4: 199-227. doi:10.1146/annurev.pathol.4.110807.092222
20. Louis D, Ohgaki H, Wiestler O, Cavenee W, Burger P, Jouvet A, Scheithauer B, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97-109. doi:10.1007/s00401-007-0243-4 (Pubitemid 47103521)
21. Lu J, Getz G, Miska E, Alvarez-Saavedra E, Lamb J, Peck D, Sweet- Cordero A, Ebert B, Mak R, Ferrando A, Downing J, Jacks T, Horvitz R, Golub T (2005) MicroRNA expression profiles classify human cancers. Nature 435:834-838. doi:10.1038/nature03702 (Pubitemid 40839735)
22. Mendell J (2005) Critical regulators of development, cellular physiology and malignancy. Cell Cycle 4:1179-1184. doi:10.4161/cc.4.9.2032
23. Moore L, Kivinen V, Liu Y, Annala M, Cogdell D, Liu X, Liu C, Sawaya R, Yli-Harja O, Shmulevich I, Fuller G, Zhang W, Nykter M (2013) Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma. J Pathol 229:449-459. doi:10.1002/path.4109
24. Nicoloso M, Calin G (2008) MicroRNA involvement in brain tumors: from bench to bedside. Brain Pathol 18:122-129. doi:10.1111/j.1750-3639.2007.00119.x
25. Rao S, Santosh V, Somasundaram K (2010) Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma. Mod Pathol 23:1404-1417. doi:10.1038/modpathol.2010.135
26. Rickert C, Sträter R, Kaatsch P, Wassmann H, Jürgens H, Dockhorn-Dworniczak B, Werner P (2001) Pediatric high-grade astrocytomas show chromosomal imbalances distinct from adult cases. Am J Pathol 158:1525-1532 (Pubitemid 32281316)
27. Schmittgen T, Livak K (2008) Analyzing real time PCR data by the comparative Ct method. Nat Protocol 3:1101-1108. doi:10.1038/nprot.2008.73 (Pubitemid 351818697)
28. Sharma S, Free A, Mei Y, Peiper C, Wang Z, Cowell K (2010) Distinct molecular signatures in pediatric infratentorial glioblastomas defined by CGH. ExpMol Pathol 89:169-174. doi:10.1016/j.yexmp.2010.06.009
29. Shi M, Wang J, Yan Z, You P, Li Y, Qian X, Yin Y, Zhao P, Wang Y, Wang F, Li N, Liu Z, Liu N, Jiang H (2012) MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1. PLoS ONE 7:1-10. doi:10.1371/journal.pone. 0032709
30. Silber J, Lim D, Petrisch C, Persson I, Maunakea K, Yu M, Vandenberg R, Ginzinger G, James D, Costello F, Bergers G, Weiss A, Alvarez-Buylla A, Hodgson G (2008) MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6:1-17. doi:10.1186/1741-7015-6-14
31. Skalsky R, Cullen B (2011) Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. PLoS ONE 6:1-11. doi:10.1371/journal.pone.0024248
32. Srinivasan S, Pia I, Somasundaram K (2011) A ten-microRNA expression signature predicts survival in glioblastoma. PLoS ONE 6:1-7. doi:10.1371/journal.pone.0017438
33. Volinia S, Calin G, Liu G, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt L, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris C, Croce M (2006) A microRNA expression signatura of human solid tumors defines cancer gene targets. PNAS 103:2257 - 2261. doi:10.1073/pnas.0510565103
34. Zeng Y (2009) Regulation of the mammalian nervous system by microRNAs. Mol Pharmacol 75:259-263. doi:10.1124/mol.108.052118
35. Zhang C, Zhang J, Hao J (2012) High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma. J Transl Med 10:1-11
36. Zhang Y, Chao T, Li R, Liu W, Chen Y, Yan X, Gong Y, Yin B, Liu W, Qiang B, Zhao J, Yuan J, Peng X (2009) MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med 87:43-51. doi:10.1007/s00109-008-0403-6
37. Zhi F, Chen X, Wang S, Xia X, Shi Y, Guan W, Shao N, Qu H, Yang C, Zhang Y, Wang Q, Wang R, Zen K, Zhang C, Zhang J, Yang Y (2010) The use of hsa-miR-21, hsa-miR-106a as prognostic indicators of astrocytoma. Eur J Cancer 46:1640-1649. doi:10.1016/j.ejca.2010.02.003