Cutaneous manifestation of α1-Antitrypsin deficiency: Panniculitis absent on biopsy

Cutis

Volumn 93, Issue 6, 2014, Pages 303-306

  Streicher, Jenna L ^a   Sheehan, Michael P ^a   Armstrong, Andrew B ^a,b   Mousdicas, Nico ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Laboratory Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ANTIINFECTIVE AGENT; DAPSONE;

ALPHA 1-ANTITRYPSIN DEFICIENCY; CASE REPORT; COMPLICATION; FEMALE; HUMAN; MIDDLE AGED; PANNICULITIS; PATHOLOGY; TREATMENT OUTCOME;

ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANTI-INFECTIVE AGENTS; DAPSONE; FEMALE; HUMANS; MIDDLE AGED; PANNICULITIS; TREATMENT OUTCOME;

EID: 84903590990     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Stoller JK, Aboussouan LS. A review of a1-antitrypsin deficiency. Am J Respir Crit Care Med. 2012;185:246-259.
2. Gross B, Grebe M, Wencker M, et al. New findings in PiZZ alpha1-antitrypsin defici ency-related panniculitis. demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy. Dermatology. 2009;218:370-375.
3. Geraminejad P, DeBloom JR 2nd, Walling HW, et al. Alpha-1-antitrypsin associated panniculitis: the MS variant. J Am Acad Dermatol. 2004;51:645-655.
4. Geller JD, Su WP. A subtle clue to the histopathologic diagnosis of early alpha 1-antitrypsin deficiency panniculitis. J Am Acad Dermatol. 1994;31(2, pt 1):241-245.
5. Smith KC, Su WP, Pittelkow MR, et al. Clinical and pathologic correlations in 96 patients with panniculitis, including 15 patients with deficient levels of alpha 1-antitrypsin. J Am Acad Dermatol. 1989;21:1192-1196.
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7. Hendrick SJ, Silverman AK, Solomon AR, et al. Alpha 1-antitrypsin deficiency associated with panniculitis. J Am Acad Dermatol. 1988;18(4, pt 1):684-692.
8. Chng WJ, Henderson CA. Suppurative panniculitis associated with alpha 1-antitrypsin deficiency (PiSZ phenotype) treated with doxycycline. Br J Dermatol. 2001;144:1282-1283.
9. Korver G, Liu C, Petersen M. Alpha 1-antitrypsin deficiency presenting with panniculitis and incidental discovery of chronic obstructive pulmonary disease. Int J Dermatol. 2007;46:1078-1080.