Selenium in sepsis - substitution, supplementation or pro-oxidative bolus?

Critical Care

Volumn 18, Issue 4, 2014, Pages

  Schomburg, Lutz ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROCALCITONIN; SELENITE; SELENOPROTEIN; SELENOPROTEIN P; SODIUM SELENITE; SELENIUM;

ANTIMICROBIAL THERAPY; BIOSYNTHESIS; CRITICALLY ILL PATIENT; DISEASE SEVERITY; HUMAN; LETTER; MORTALITY; MULTICENTER STUDY (TOPIC); MULTIVARIATE ANALYSIS; NONHUMAN; OPTIMAL DRUG DOSE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SELENIUM DEFICIENCY; SEPSIS; SUPPLEMENTATION; CRITICAL ILLNESS; DIET SUPPLEMENTATION; FEMALE; MALE; POSTOPERATIVE CARE; PROCEDURES;

CRITICAL ILLNESS; DIETARY SUPPLEMENTS; FEMALE; HUMANS; MALE; POSTOPERATIVE CARE; SELENIUM; SEPSIS; SODIUM SELENITE;

EID: 84903588712     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc13963     Document Type: Letter

References (5)

1. Sakr Y, Maia VP, Santos C, Stracke J, Zeidan M, Bayer O, Reinhart K. Adjuvant selenium supplementation in the form of sodium selenite in postoperative critically ill patients with severe sepsis. Crit Care 2014, 18:R68. 10.1186/cc13825, 4056529, 24716537.
2. Forceville X, Vitoux D, Gauzit R, Combes A, Lahilaire P, Chappuis P. Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients. Crit Care Med 1998, 26:1536-1544. 10.1097/00003246-199809000-00021, 9751590.
3. Hollenbach B, Morgenthaler NG, Struck J, Alonso C, Bergmann A, Kohrle J, Schomburg L. New assay for the measurement of selenoprotein P as a sepsis biomarker from serum. J Trace Elements Med Biol 2008, 22:24-32.
4. Stoedter M, Renko K, Hog A, Schomburg L. Selenium controls the sex-specific immune response and selenoprotein expression during the acute-phase response in mice. Biochem J 2010, 429:43-51. 10.1042/BJ20091868, 20370716.
5. Angstwurm MW, Engelmann L, Zimmermann T, Lehmann C, Spes CH, Abel P, Strauss R, Meier-Hellmann A, Insel R, Radke J, Schüttler J, Gärtner R. Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med 2007, 35:118-126. 10.1097/01.CCM.0000251124.83436.0E, 17095947.