Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Rouhier, Matthew F ^a   Raphemot, Rene ^b   Denton, Jerod S ^b   Piermarini, Peter M ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSECTICIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR1.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR7.1; POTASSIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG; VU 573; VU 590; VU 608;

ADULT; AEDES AEGYPTI; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; FEMALE; HEMOLYMPH; HUMAN; IN VITRO STUDY; INSECTICIDE RESISTANCE; NONHUMAN; URINARY EXCRETION; VALIDATION PROCESS; AEDES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IC50; METABOLISM; OOCYTE; TRANSMISSION; VIROLOGY; YELLOW FEVER; YELLOW FEVER FLAVIVIRUS;

AEDES; ANIMALS; CELL LINE; FEMALE; GENE EXPRESSION; HUMANS; INHIBITORY CONCENTRATION 50; INSECTICIDES; OOCYTES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; YELLOW FEVER; YELLOW FEVER VIRUS;

EID: 84903548507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100700     Document Type: Article

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