Delineation of concentration ranges and longitudinal changes of human plasma protein variants

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Trenchevska, Olgica ^a,b   Phillips, David A ^b   Nelson, Randall W ^a   Nedelkov, Dobrin ^a,b,c  

^a Arizona State University   (United States)

^b Intrinsic Bioprobes   (United States)

^c Institute for Population Proteomics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; CYSTATIN C; PLASMA PROTEIN; PREALBUMIN; PROTEIN VARIANT; RETINOL BINDING PROTEIN; ISOPROTEIN; MUTANT PROTEIN;

ADULT; AGE; ARTICLE; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); FEMALE; GENDER; GEOGRAPHIC ORIGIN; HUMAN; IMMUNOASSAY; LONGITUDINAL STUDY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PROTEIN ANALYSIS; PROTEIN PROCESSING; PUBLICATION; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; METABOLISM; MOLECULAR WEIGHT; PLASMA; REFERENCE VALUE; UNITED STATES;

ADULT; AGE FACTORS; BETA 2-MICROGLOBULIN; BLOOD PROTEINS; CYSTATIN C; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MOLECULAR WEIGHT; MUTANT PROTEINS; PLASMA; PREALBUMIN; PROTEIN ISOFORMS; REFERENCE VALUES; RETINOL-BINDING PROTEINS; TENNESSEE; TEXAS;

EID: 84903538459     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100713     Document Type: Article

References (48)

1. Roy B, Haupt LM, Griffiths LR (2013) Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity. Curr Genomics 14: 182-194.
2. Schaefer C, Meier A, Rost B, Bromberg Y (2012) SNPdbe: constructing an nsSNP functional impacts database. Bioinformatics 28: 601-602.
3. Wu JR, Zeng R (2012) Molecular basis for population variation: from SNPs to SAPs. FEBS Lett 586: 2841-2845.
4. Farley AR, Link AJ (2009) Identification and quantification of protein posttranslational modifications. Methods Enzymol 463: 725-763.
5. Basset P, Beuzard Y, Garel MC, Rosa J (1978) Isoelectric focusing of human hemoglobin: its application to screening, to the characterization of 70 variants, and to the study of modified fractions of normal hemoglobins. Blood 51: 971-982. (Pubitemid 8342564)
6. Kueppers F, Christopherson MJ (1978) Alpha1-antitrypsin: further genetic heterogeneity revealed by isoelectric focusing. Am J Hum Genet 30: 359-365. (Pubitemid 8397612)
7. Mifflin TE, Hortin G, Bruns DE (1986) Electrophoretic assays of amylase isoenzymes and isoforms. Clin Lab Med 6: 583-599. (Pubitemid 16053901)
8. Pettersson T, Carlström A, Jörnvall H (1987) Different types of microheterogeneity of human thyroxine-binding prealbumin. Biochemistry 26: 4572-4583. (Pubitemid 17137067)
9. Kim H, Eliuk S, Deshane J, Meleth S, Sanderson T, et al. (2007) 2D gel proteomics: an approach to study age-related differences in protein abundance or isoform complexity in biological samples. Methods Mol Biol 371: 349-391. (Pubitemid 350183436)
10. Corzett TH, Fodor IK, Choi MW, Walsworth VL, Turteltaub KW, et al. (2010) Statistical analysis of variation in the human plasma proteome. J Biomed Biotechnol 2010: 258494.
11. Jackson D, Herath A, Swinton J, Bramwell D, Chopra R, et al. (2009) Considerations for powering a clinical proteomics study: Normal variability in the human plasma proteome. Proteomics Clin Appl 3: 394-407.
12. Ignjatovic V, Lai C, Summerhayes R, Mathesius U, Tawfilis S, et al. (2011) Age-related differences in plasma proteins: how plasma proteins change from neonates to adults. PLoS One 6: e17213.
13. Siuti N, Kelleher NL (2007) Decoding protein modifications using top-down mass spectrometry. Nat Methods 4: 817-821. (Pubitemid 350055578)
14. Zhang H, Ge Y (2011) Comprehensive analysis of protein modifications by topdown mass spectrometry. Circ Cardiovasc Genet 4: 711.
15. Stastna M, Van Eyk JE (2012) Analysis of protein isoforms: can we do it better? Proteomics 12: 2937-2948.
16. Wu J, Pungaliya P, Kraynov E, Bates B (2012) Identification and quantification of osteopontin splice variants in the plasma of lung cancer patients using immunoaffinity capture and targeted mass spectrometry. Biomarkers 17: 125-133.
17. Végvári A, Sjödin K, Rezeli M, Malm J, Lilja H, et al. (2013) Identification of a novel proteoform of prostate specific antigen (SNP-L132I) in clinical samples by multiple reaction monitoring. Mol Cell Proteomics 12: 2761-2773.
18. Su ZD, Sun L, Yu DX, Li RX, Li HX, et al. (2011) Quantitative detection of single amino acid polymorphisms by targeted proteomics. J Mol Cell Biol 3: 309-315.
19. He K, Wen XY, Li AL, Li T, Wang J, et al. (2013) Serum peptidome variations in a healthy population: reference to identify cancer-specific peptides. PLoS One 8: e63724.
20. Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, et al. (2011) Analysis of intact protein isoforms by mass spectrometry. J Biol Chem 286: 25451-25458.
21. Nelson RW, Krone JR, Bieber AL, Williams P (1995) Mass spectrometric immunoassay. Anal Chem 67: 1153-1158.
22. Nedelkov D, Tubbs KA, Niederkofler EE, Kiernan UA, Nelson RW (2004) High-throughput comprehensive analysis of human plasma proteins: a step toward population proteomics. Anal Chem 76: 1733-1737. (Pubitemid 38338422)
23. Nedelkov D, Kiernan UA, Niederkofler EE, Tubbs KA, Nelson RW (2005) Investigating diversity in human plasma proteins. Proc Natl Acad Sci U S A 102: 10852-10857. (Pubitemid 41105956)
24. Nedelkov D, Phillips DA, Tubbs KA, Nelson RW (2007) Investigation of human protein variants and their frequency in the general population. Mol Cell Proteomics 6: 1183-1187. (Pubitemid 47099228)
25. Trenchevska O, Kamcheva E, Nedelkov D (2010) Mass spectrometric immunoassay for quantitative determination of protein biomarker isoforms. J Proteome Res 9: 5969-5973.
26. Trenchevska O, Nedelkov D (2011) Targeted quantitative mass spectrometric immunoassay for human protein variants. Proteome Sci 9: 19.
27. Kiernan UA, Phillips DA, Trenchevska O, Nedelkov D (2011) Quantitative mass spectrometry evaluation of human retinol binding protein 4 and related variants. PLoS One 6: e17282.
28. Trenchevska O, Kamcheva E, Nedelkov D (2011) Mass spectrometric immunoassay for quantitative determination of transthyretin and its variants. Proteomics 11: 3633-3641.
29. Manicourt D, Brauman H, Orloff S (1978) Plasma and urinary levels of beta2 microglobulin in rheumatoid arthritis. Ann Rheum Dis 37: 328-332. (Pubitemid 9017953)
30. Schardijn GH, Statius van Eps LW (1987) Beta 2-microglobulin: its significance in the evaluation of renal function. Kidney Int 32: 635-641. (Pubitemid 17152392)
31. Nissen MH, Plesner T, Rorth M (1984) Modification of beta 2-microglobulin in serum from patients with small cell carcinoma of the lung - correlation with the clinical course. Clin Chim Acta 141: 41-50. (Pubitemid 14098763)
32. Plesner T, Wiik A (1979) Demonstration of electrophoretic heterogeneity of serum beta 2-microglobulin in systemic lupus erythematosus and rheumatoid arthritis: evidence against autoantibodies to beta 2-microglobulin. Scand J Immunol 9: 247-254. (Pubitemid 9130102)
33. Randers E, Erlandsen EJ (1999) Serum cystatin C as an endogenous marker of the renal function-a review. Clin Chem Lab Med 37: 389-395. (Pubitemid 29218957)
34. Randers E, Kristensen JH, Erlandsen EJ, Danielsen H (1998) Serum cystatin C as a marker of the renal function. Scand J Clin Lab Invest 58: 585-592. (Pubitemid 29016385)
35. Beetham R, Dawnay A, Landon J, Cattell WR (1985) A radioimmunoassay for retinol-binding protein in serum and urine. Clin Chem 31: 1364-1367. (Pubitemid 16041933)
36. Jaconi S, Rose K, Hughes GJ, Saurat JH, Siegenthaler G (1995) Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure. J Lipid Res 36: 1247-1253.
37. Saraiva MJ (2001) Transthyretin amyloidosis: a tale of weak interactions. FEBS Lett 498: 201-203.
38. Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration. FEBS J 274: 1637-1650. (Pubitemid 46426902)
39. Connors LH, Lim A, Prokaeva T, Roskens VA, Costello CE (2003) Tabulation of human transthyretin (TTR) variants, 2003. Amyloid 10: 160-184. (Pubitemid 37372400)
40. Nissen MH, Roepstorff P, Thim L, Dunbar B, Fothergill JE (1990) Limited proteolysis of beta 2-microglobulin at Lys-58 by complement component C1s. Eur J Biochem 189: 423-429. (Pubitemid 20146028)
41. Grubb A, Lofberg H (1982) Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis. Proc Natl Acad Sci U S A 79: 3024-3027. (Pubitemid 12058609)
42. Erlandsen EJ, Randers E, Kristensen JH (1998) Reference intervals for serum cystatin C and serum creatinine in adults. Clin Chem Lab Med 36: 393-397. (Pubitemid 28379049)
43. Kanai M, Raz A, Goodman DS (1968) Retinol-binding protein: the transport protein for vitamin A in human plasma. J Clin Invest 47: 2025-2044.
44. Myron Johnson A, Merlini G, Sheldon J, Ichihara K, Scientific Division Committee on Plasma Proteins (C-PP) ItFoCCaLMI (2007) Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition. Clin Chem Lab Med 45: 419-426.
45. Yates JR, Ruse CI, Nakorchevsky A (2009) Proteomics by mass spectrometry: approaches, advances, and applications. Annu Rev Biomed Eng 11: 49-79.
46. Anderson NL, Anderson NG, Haines LR, Hardie DB, Olafson RW, et al. (2004) Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA). J Proteome Res 3: 235-244. (Pubitemid 38500990)
47. Prakash A, Rezai T, Krastins B, Sarracino D, Athanas M, et al. (2012) Interlaboratory reproducibility of selective reaction monitoring assays using multiple upfront analyte enrichment strategies. J Proteome Res 11: 3986-3995.
48. Petitclerc C (2004) Normality: the unreachable star? Clin Chem Lab Med 42: 698-701.