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Volumn 59, Issue 7, 2014, Pages 1442-1451

HOXA10 promotes cell invasion and MMP-3 expression via TGFβ2-mediated activation of the p38 MAPK pathway in pancreatic cancer cells

Author keywords

HOXA10; Invasion; MMP 3; p38 MAPK pathway; Pancreatic cancer; TGF 2

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; BLOCKING ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; STROMELYSIN; TRANSCRIPTION FACTOR HOXA10; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84903524025     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-014-3033-6     Document Type: Article
Times cited : (34)

References (28)
  • 3
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • DOI 10.1038/sj.onc.1210392, PII 1210392
    • Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene. 2007;26:3100-3112. (Pubitemid 46763006)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 4
    • 12944249378 scopus 로고    scopus 로고
    • Expression of 11 HOX genes is deregulated in esophageal squamous cell carcinoma
    • Chen KN, Gu ZD, Ke Y, Li AY, Shi XT, Xu GW. Expression of 11 HOX genes is deregulated in esophageal squamous cell carcinoma. Clin Cancer Res. 2005;11:1044-1049. (Pubitemid 40175752)
    • (2005) Clinical Cancer Research , vol.11 , Issue.3 , pp. 1044-1049
    • Chen, K.-N.1    Gu, Z.-D.2    Ke, Y.3    Li, J.-Y.4    Shi, X.-T.5    Xu, G.-W.6
  • 5
    • 34249930780 scopus 로고    scopus 로고
    • Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma
    • Takahashi O, Hamada J, Abe M, et al. Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma. Oncol Rep. 2007;17:753-760.
    • (2007) Oncol Rep , vol.17 , pp. 753-760
    • Takahashi, O.1    Hamada, J.2    Abe, M.3
  • 7
    • 76049096034 scopus 로고    scopus 로고
    • State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma
    • Yamatoji M, Kasamatsu A, Yamano Y, et al. State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncol Rep. 2010;23:61-67.
    • (2010) Oncol Rep , vol.23 , pp. 61-67
    • Yamatoji, M.1    Kasamatsu, A.2    Yamano, Y.3
  • 8
    • 84875954610 scopus 로고    scopus 로고
    • PTEN loss and HOXA10 expression are associated with ovarian endometrioid adenocarcinoma differentiation and progression
    • Tanwar PS, Kaneko-Tarui T, Lee HJ, Zhang L, Teixeira JM. PTEN loss and HOXA10 expression are associated with ovarian endometrioid adenocarcinoma differentiation and progression. Carcinogenesis. 2013;34:893-901.
    • (2013) Carcinogenesis , vol.34 , pp. 893-901
    • Tanwar, P.S.1    Kaneko-Tarui, T.2    Lee, H.J.3    Zhang, L.4    Teixeira, J.M.5
  • 9
    • 74749087064 scopus 로고    scopus 로고
    • The Mullerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions
    • Ko SY, Lengyel E, Naora H. The Mullerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol Cell Endocrinol. 2010;317: 112-119.
    • (2010) Mol Cell Endocrinol , vol.317 , pp. 112-119
    • Ko, S.Y.1    Lengyel, E.2    Naora, H.3
  • 10
    • 12244276678 scopus 로고    scopus 로고
    • HOXA10 regulates p53 expression and matrigel invasion in human breast cancer cells
    • Chu MC, Selam FB, Taylor HS. HOXA10 regulates p53 expression and matrigel invasion in human breast cancer cells. Cancer Biol Ther. 2004;3:568-572. (Pubitemid 41351131)
    • (2004) Cancer Biology and Therapy , vol.3 , Issue.6 , pp. 568-572
    • Chu, M.C.1    Selam, F.B.2    Taylor, H.S.3
  • 11
    • 84860487053 scopus 로고    scopus 로고
    • Upregulation of HOXA10 in gastric cancer with the intestinal mucin phenotype: Reduction during tumor progression and favorable prognosis
    • Sentani K, Oue N, Naito Y, et al. Upregulation of HOXA10 in gastric cancer with the intestinal mucin phenotype: reduction during tumor progression and favorable prognosis. Carcinogenesis. 2012;33:1081-1088.
    • (2012) Carcinogenesis , vol.33 , pp. 1081-1088
    • Sentani, K.1    Oue, N.2    Naito, Y.3
  • 12
    • 0035865438 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: Clinicopathologic and prognostic significance of matrilysin expression
    • Yamamoto H, Itoh F, Iku S, et al. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of Matrilysin expression. J Clin Oncol. 2001; 19:1118-1127. (Pubitemid 32176289)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.4 , pp. 1118-1127
    • Yamamoto, H.1    Itoh, F.2    Iku, S.3    Adachi, Y.4    Fukushima, H.5    Sasaki, S.6    Mukaiya, M.7    Hirata, K.8    Imai, K.9
  • 14
    • 84861540139 scopus 로고    scopus 로고
    • HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells
    • Shah CA, Bei L, Wang H, Platanias LC, Eklund EA. HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells. J Biol Chem. 2012;287: 18230-18248.
    • (2012) J Biol Chem , vol.287 , pp. 18230-18248
    • Shah, C.A.1    Bei, L.2    Wang, H.3    Platanias, L.C.4    Eklund, E.A.5
  • 15
    • 78951489486 scopus 로고    scopus 로고
    • HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells
    • Shah CA, Wang H, Bei L, Platanias LC, Eklund EA. HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells. J Biol Chem. 2011;286: 3161-3176.
    • (2011) J Biol Chem , vol.286 , pp. 3161-3176
    • Shah, C.A.1    Wang, H.2    Bei, L.3    Platanias, L.C.4    Eklund, E.A.5
  • 16
    • 73349138253 scopus 로고    scopus 로고
    • HOXA10 is overexpressed in human ovarian clear cell adenocarcinoma and correlates with poor survival
    • Li B, Jin H, Yu Y, et al. HOXA10 is overexpressed in human ovarian clear cell adenocarcinoma and correlates with poor survival. Int J Gynecol Cancer. 2009;19:1347-1352.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1347-1352
    • Li, B.1    Jin, H.2    Yu, Y.3
  • 17
    • 84862789099 scopus 로고    scopus 로고
    • miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10
    • Chen Y, Zhang J, Wang H, et al. miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. BMC Cancer. 2012;12:111.
    • (2012) BMC Cancer , vol.12 , pp. 111
    • Chen, Y.1    Zhang, J.2    Wang, H.3
  • 18
    • 3042736017 scopus 로고    scopus 로고
    • Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and matrigel
    • DOI 10.1002/ijc.20207
    • Baba M, Itoh K, Tatsuta M. Glycine-extended gastrin induces matrix metalloproteinase-1-and-3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel. Int J Cancer. 2004;111:23-31. (Pubitemid 38859279)
    • (2004) International Journal of Cancer , vol.111 , Issue.1 , pp. 23-31
    • Baba, M.1    Itoh, K.2    Tatsuta, M.3
  • 19
    • 67449084623 scopus 로고    scopus 로고
    • The effect of TGF-beta2 on MMP-2 production and activity in highly metastatic human bladder carcinoma cell line 5637
    • Dehnavi E, Soheili ZS, Samiei S, Ataei Z, Aryan H. The effect of TGF-beta2 on MMP-2 production and activity in highly metastatic human bladder carcinoma cell line 5637. Cancer Invest. 2009;27:568-574.
    • (2009) Cancer Invest , vol.27 , pp. 568-574
    • Dehnavi, E.1    Soheili, Z.S.2    Samiei, S.3    Ataei, Z.4    Aryan, H.5
  • 20
    • 34248599025 scopus 로고    scopus 로고
    • The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2
    • DOI 10.1038/sj.bjc.6603766, PII 6603766
    • Arslan F, Bosserhoff AK, Nickl-Jockschat T, Doerfelt A, Bogdahn U, Hau P. The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2. Br J Cancer. 2007;96:1560-1568. (Pubitemid 46762960)
    • (2007) British Journal of Cancer , vol.96 , Issue.10 , pp. 1560-1568
    • Arslan, F.1    Bosserhoff, A.-K.2    Nickl-Jockschat, T.3    Doerfelt, A.4    Bogdahn, U.5    Hau, P.6
  • 22
    • 47949103896 scopus 로고    scopus 로고
    • Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to- mesenchymal transition
    • Do TV, Kubba LA, Du H, Sturgis CD, Woodruff TK. Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to- mesenchymal transition. Mol Cancer Res. 2008;6:695-705.
    • (2008) Mol Cancer Res , vol.6 , pp. 695-705
    • Do, T.V.1    Kubba, L.A.2    Du, H.3    Sturgis, C.D.4    Woodruff, T.K.5
  • 23
    • 0036021837 scopus 로고    scopus 로고
    • Regulation of colony-stimulating factor-induced human myelopoiesis by transforming growth factor-beta isoforms
    • DOI 10.1080/13684730216400
    • Salzman SA, Mazza JJ, Burmester JK. Regulation of colony-stimulating factor-induced human myelopoiesis by transforming growth factor-beta isoforms. Cytokines Cell Mol Ther. 2002;7: 31-36. (Pubitemid 34831967)
    • (2002) Cytokines, Cellular and Molecular Therapy , vol.7 , Issue.1 , pp. 31-36
    • Salzman, S.A.1    Mazza, J.J.2    Burmester, J.K.3
  • 24
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway Activation and function
    • DOI 10.1016/S0898-6568(99)00071-6, PII S0898656899000716
    • Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal. 2000;12:1-13. (Pubitemid 30017963)
    • (2000) Cellular Signalling , vol.12 , Issue.1 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 25
    • 84869077763 scopus 로고    scopus 로고
    • Pancreatic cancer circulating tumour cells express a cell motility gene signature that predicts survival after surgery
    • Sergeant G, van Eijsden R, Roskams T, Van Duppen V, Topal B. Pancreatic cancer circulating tumour cells express a cell motility gene signature that predicts survival after surgery. BMC Cancer. 2012;12:527.
    • (2012) BMC Cancer , vol.12 , pp. 527
    • Sergeant, G.1    Van Eijsden, R.2    Roskams, T.3    Van Duppen, V.4    Topal, B.5
  • 26
    • 79952383925 scopus 로고    scopus 로고
    • KITENIN is associated with activation of AP-1 target genes via MAPK cascades signaling in human hepatocellular carcinoma progression
    • Cho SB, Park YL, Park SJ, et al. KITENIN is associated with activation of AP-1 target genes via MAPK cascades signaling in human hepatocellular carcinoma progression. Oncol Res. 2011;19: 115-123.
    • (2011) Oncol Res , vol.19 , pp. 115-123
    • Cho, S.B.1    Park, Y.L.2    Park, S.J.3
  • 27
    • 33646361573 scopus 로고    scopus 로고
    • Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38
    • DOI 10.1016/j.cellsig.2005.09.004, PII S0898656805002391
    • Dreissigacker U, Mueller MS, Unger M, et al. Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38. Cell Signal. 2006;18:1156-1168. (Pubitemid 43674042)
    • (2006) Cellular Signalling , vol.18 , Issue.8 , pp. 1156-1168
    • Dreissigacker, U.1    Mueller, M.S.2    Unger, M.3    Siegert, P.4    Genze, F.5    Gierschik, P.6    Giehl, K.7
  • 28
    • 84860543431 scopus 로고    scopus 로고
    • Norepinephrine stimulates pancreatic cancer cell proliferation, migration and invasion via beta-adrenergic receptor-dependent activation of P38/MAPK pathway
    • Huang XY, Wang HC, Yuan Z, Huang J, Zheng Q. Norepinephrine stimulates pancreatic cancer cell proliferation, migration and invasion via beta-adrenergic receptor-dependent activation of P38/MAPK pathway. Hepatogastroenterology. 2012;59:889-893.
    • (2012) Hepatogastroenterology , vol.59 , pp. 889-893
    • Huang, X.Y.1    Wang, H.C.2    Yuan, Z.3    Huang, J.4    Zheng, Q.5


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